YRC Public Data Repository - Protein Structure Prediction

Protein:	YDJI_ECOLI
Organism:	Escherichia coli
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDJI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|89211620, gi\|... - gi\|89211620\|ref\|ZP_01189975.1\| Ketose-bisphosphate aldolase, class-II:Fructose-1,6-bisphosphate aldo...	372.0	[0..2]	[277..3]
gi\|77995172, gi\|... - gi\|78043057\|ref\|YP_359000.1\| putative aldolase [Carboxydothermus hydrogenoformans Z-2901], gi\|779951...	368.0	[0..2]	[277..3]
gi\|20806666 - gi\|20806666\|ref\|NP_621837.1\| Fructose/tagatose bisphosphate aldolase [Thermoanaerobacter tengcongens... gi\|20806666, gi\|... - gi\|20806666\|ref\|NP_621837.1\| putative aldolase [Thermoanaerobacter tengcongensis MB4], gi\|20515116\|g...	365.0	[0..1]	[277..1]
gi\|76795972, gi\|... - gi\|76795972\|ref\|ZP_00778342.1\| Ketose-bisphosphate aldolase, class-II:Fructose-1,6-bisphosphate aldo... gi\|242231659, gi... - gi\|242256845\|ref\|ZP_04801728.1\| fructose-1,6-bisphosphate aldolase, class II [Thermoanaerobacter sp.... gi\|241884706, gi... - gi\|241902905\|ref\|ZP_04787635.1\| fructose-1,6-bisphosphate aldolase, class II [Thermoanaerobacter bro... gi\|166853001, gi... - gi\|167038761\|ref\|YP_001661746.1\| putative aldolase [Thermoanaerobacter sp. X514], gi\|166853001\|gb\|AB...	362.0	[0..1]	[277..1]
gi\|56381763, gi\|... - gi\|56421921\|ref\|YP_149239.1\| fructose-bisphosphate aldolase [Geobacillus kaustophilus HTA426], gi\|56... gi\|229497815, gi... - gi\|229497815\|ref\|ZP_04391514.1\| fructose-1,6-bisphosphate aldolase, class II [Geobacillus sp. Y412MC... gi\|221087046, gi... - gi\|221087046\|ref\|ZP_03556586.1\| fructose-1,6-bisphosphate aldolase, class II [Geobacillus sp. Y412MC...	362.0	[0..2]	[277..3]
ALF_GEOSE - Fructose-bisphosphate aldolase OS=Geobacillus stearothermophilus GN=fba PE=3 SV=3	361.0	[0..2]	[277..3]
gi\|41057054, gi\|... - gi\|41057054\|ref\|NP_957657.1\| putative class II fructose-1,6-bisphosphate aldolase [Bacillus methanol...	360.0	[0..2]	[277..3]
gi\|219541095, gi... - gi\|219670835\|ref\|YP_002461270.1\| fructose-1,6-bisphosphate aldolase, class II [Desulfitobacterium ha...	359.0	[0..2]	[277..3]
gi\|152977521, gi... - gi\|89201426\|ref\|ZP_01180166.1\| Ketose-bisphosphate aldolase, class-II:Fructose-1,6-bisphosphate aldo...	358.0	[0..2]	[277..3]
gi\|88924796, gi\|... - gi\|88945570\|ref\|ZP_01148738.1\| Ketose-bisphosphate aldolase, class-II:Fructose-1,6-bisphosphate aldo...	357.0	[0..2]	[277..3]

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Predicted Domain #1

Region A:
Residues: [1-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLADIRYWEN DATNKHYAIA HFNVWNAEML MGVIDAAEEA KSPVIISFGT GFVGNTSFED  60
   61 FSHMMVSMAQ KATVPVITHW DHGRSMEIIH NAWTHGMNSL MRDASAFDFE ENIRLTKEAV 120
  121 DFFHPLGIPV EAELGHVGNE TVYEEALAGY HYTDPDQAAE FVERTGCDSL AVAIGNQHGV 180
  181 YTSEPQLNFE VVKRVRDAVS VPLVLHGASG ISDADIKTAI SLGIAKINIH TELCQAAMVA 240
  241 VKENQDQPFL HLEREVRKAV KERALEKIKL FGSDGKAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	91.69897
Match:	1gvfA
Description:	Tagatose-1,6-bisphosphate aldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	3.04075198078553	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	2.06219969438898	bayes_pls_golite062009
transaldolase activity	1.83913207529502	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.50014841201184	bayes_pls_golite062009
aldehyde-lyase activity	0.85265356790496	bayes_pls_golite062009
lyase activity	0.437176828950096	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: