YRC Public Data Repository - Protein Structure Prediction

Protein:	YCJS_ECOLI
Organism:	Escherichia coli
Length:	351 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCJS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|146296197, gi... - gi\|82499511\|ref\|ZP_00884954.1\| NADH-dependent dyhydrogenase [Caldicellulosiruptor saccharolyticus DS...	278.0	[0..8]	[351..2]
gi\|254592308, gi... - gi\|254792908\|ref\|YP_003077745.1\| predicted oxidoreductase, NADH-binding [Escherichia coli O157:H7 st... gi\|13361359, gi\|... - gi\|15831148\|ref\|NP_309921.1\| putative dehydrogenase [Escherichia coli O157:H7 str. Sakai], gi\|133613... gi\|195937981 - gi\|195937981\|ref\|ZP_03083363.1\| putative dehydrogenase [Escherichia coli O157:H7 str. EC4024] gi\|208811007, gi... - gi\|208811007\|ref\|ZP_03252840.1\| gfo/idh/mocA family protein [Escherichia coli O157:H7 str. EC4206], ... gi\|209159213, gi... - gi\|209397813\|ref\|YP_002270375.1\| gfo/idh/mocA family protein [Escherichia coli O157:H7 str. EC4115],... gi\|189367059, gi... - gi\|189367059\|gb\|EDU85475.1\| oxidoreductase family [Escherichia coli O157:H7 str. EC4501], gi\|1687626... gi\|168775140, gi... - gi\|187769319\|gb\|EDU33163.1\| gfo/idh/mocA family [Escherichia coli O157:H7 str. EC4196], gi\|168775140... gi\|25305064, gi\|... - pir\|\|C85753 probable dehydrogenase ycjS [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|168782844, gi... - gi\|188999721\|gb\|EDU68707.1\| oxidoreductase family [Escherichia coli O157:H7 str. EC4076], gi\|1687828... gi\|168799625, gi... - gi\|189377957\|gb\|EDU96373.1\| oxidoreductase family protein [Escherichia coli O157:H7 str. EC508], gi\|... gi\|12515454, gi\|... - gi\|15801855\|ref\|NP_287873.1\| putative dehydrogenase [Escherichia coli O157:H7 EDL933], gi\|12515454\|g... gi\|13361359, gi\|... - gi\|15831148\|ref\|NP_309921.1\| putative dehydrogenase [Escherichia coli O157:H7], gi\|13361359\|dbj\|BAB3... gi\|188016564, gi... - gi\|188016564\|gb\|EDU54686.1\| gfo/idh/mocA family [Escherichia coli O157:H7 str. EC4113], gi\|168749045...	267.0	[0..1]	[351..1]
gi\|74312318, gi\|... - gi\|74312318\|ref\|YP_310737.1\| putative dehydrogenase [Shigella sonnei Ss046], gi\|73855795\|gb\|AAZ88502...	267.0	[0..1]	[351..1]
gi\|115512692, gi... - gi\|117623568\|ref\|YP_852481.1\| oxidoreductase YcjS [Escherichia coli APEC O1], gi\|115512692\|gb\|ABJ007... gi\|91072183, gi\|... - gi\|91210609\|ref\|YP_540595.1\| oxidoreductase YcjS [Escherichia coli UTI89], gi\|91072183\|gb\|ABE07064.1... gi\|237705345, gi... - gi\|237705345\|ref\|ZP_04535826.1\| oxidoreductase YcjS [Escherichia sp. 3_2_53FAA], gi\|226900102\|gb\|EEH... gi\|218365071, gi... - gi\|218558302\|ref\|YP_002391215.1\| putative oxidoreductase, NADH-binding [Escherichia coli S88], gi\|21...	267.0	[0..1]	[351..1]
gi\|76796791, gi\|... - gi\|76796791\|ref\|ZP_00779144.1\| Oxidoreductase, N-terminal:Oxidoreductase, C-terminal [Thermoanaeroba... gi\|241884318, gi... - gi\|241903252\|ref\|ZP_04787978.1\| oxidoreductase domain protein [Thermoanaerobacter brockii subsp. fin...	265.0	[0..5]	[349..1]
gi\|167039723, gi... - gi\|167039723\|ref\|YP_001662708.1\| oxidoreductase domain-containing protein [Thermoanaerobacter sp. X5... gi\|242256503, gi... - gi\|242256503\|ref\|ZP_04801393.1\| oxidoreductase domain protein [Thermoanaerobacter sp. X513], gi\|2422...	265.0	[0..5]	[349..1]
gi\|26108053, gi\|... - gi\|26247651\|ref\|NP_753691.1\| oxidoreductase ycjS [Escherichia coli CFT073], gi\|26108053\|gb\|AAN80253....	264.0	[0..1]	[351..1]
gi\|10174784, gi\|... - gi\|15614728\|ref\|NP_243031.1\| hypothetical protein BH2165 [Bacillus halodurans C-125], gi\|10174784\|db... gi\|25490299 - pir\|\|E83920 hypothetical protein BH2165 [imported] - Bacillus halodurans (strain C-125)	263.0	[0..5]	[349..1]
gi\|30041082, gi\|... - gi\|30062834\|ref\|NP_837005.1\| putative dehydrogenase [Shigella flexneri 2a str. 2457T], gi\|30041082\|g...	261.0	[0..1]	[351..1]
gi\|75259427, gi\|... - gi\|75259427\|ref\|ZP_00730746.1\| COG0673: Predicted dehydrogenases and related proteins [Escherichia c... gi\|193066913, gi... - gi\|75240039\|ref\|ZP_00724000.1\| COG0673: Predicted dehydrogenases and related proteins [Escherichia c... gi\|75212755 - gi\|75212755\|ref\|ZP_00712753.1\| COG0673: Predicted dehydrogenases and related proteins [Escherichia c...	261.0	[0..5]	[351..1]

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Predicted Domain #1

Region A:
Residues: [1-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSAMTSSPL RVAIIGAGQV ADKVHASYYC TRNDLELVAV CDSRLSQAQA LAEKYGNASV  60
   61 WDDPQAMLLA VKPDVVSVCS PNRFHYEHTL MALEAGCHVM CEKPPAMTPE QAREMCDTAR 120
  121 KLGKVLAYDF HHRFALDTQQ LREQVTNGVL GEIYVTTARA LRRCGVPGWG VFTNKELQGG 180
  181 GPLIDIGIHM LDAAMYVLGF PAVKSVNAHS FQKIGTQKSC GQFGEWDPAT YSVEDSLFGT 240
  241 IEFHNGGILW LETSFALNIR EQSIMNVSFC GDKAGATLFP AHIYTDNNGE LMTLMQREIA 300
  301 DDNRHLRSME AFINHVQGKP VMIADAEQGY IIQQLVAALY QSAETGTRVE L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.522879
Match:	1h6aA
Description:	Glucose-fructose oxidoreductase, N-terminal domain; Glucose-fructose oxidoreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.16785883389468	bayes_pls_golite062009
oxidoreductase activity	1.13814306448308	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.133527946988034	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.132424363428837	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: