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View Structure Prediction Details

Protein: unc-16
Organism: Caenorhabditis elegans
Length: 546 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-16.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
409.0 [0..13] [543..1152]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
391.0 [0..33] [540..975]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
383.0 [0..44] [540..1060]
gi|116200089, gi... - gi|88179479|gb|EAQ86947.1| hypothetical protein CHGG_08200 [Chaetomium globosum CBS 148.51], gi|1162...
373.0 [0..43] [541..948]
gi|71675046, gi|... - gi|71675046|ref|ZP_00672792.1| G-protein beta WD-40 repeat [Trichodesmium erythraeum IMS101], gi|716...
372.0 [0..44] [540..829]
gi|115443476, gi... - gi|115443476|ref|XP_001218545.1| hypothetical protein ATEG_09923 [Aspergillus terreus NIH2624], gi|1...
367.0 [0..43] [540..643]
gi|70986621, gi|... - gi|70986621|ref|XP_748801.1| Pfs, NACHT and WD domain protein [Aspergillus fumigatus Af293], gi|6684...
364.0 [0..65] [542..892]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTKTSNHR PELEDEIKRA RNLDARESEL DEWQSSSLVW VVSSNQGKSL IAVLDANNPN  60
   61 NIIETFPACD SHLLCIQAVS GVMEGEPEMN EEQSKKYLSG GGKIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [106-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLPEGLDGTD LGACEWVELR KMEDSEDGVP TYCSNDMKPS PKRTRDFSIS EVAPVDSSAP  60
   61 VKEDPLPPPA NRPGGRAALP PHIRDAMSKY DGVSGQMSGA LPTVWMGGQN QYIYIHSAVT 120
  121 AWKQCLRRIK MPDAVLSIVH YKSRIFAALA NGTIAIFHRN KHGEWSDEGY HSLRVGSATS 180
  181 SVRSLCLVST NIWATYKNCV VVLDAESLQI VKVFAAHPRK DSQVRNMQWV GAGVWLSIRL 240
  241 DSTLRLYHAH TYEHLQDVDI EPYVTKMLGT SKLDFSYMRT TALLVSNRRL WIGTGTGVII 300
  301 SVPFSGQLEK KIETKDSKRP AGPGGLVRVY GATSENATND EKTNDDFIPY CNLAHAQLSF 360
  361 HGHKDSVKFF LGVPGASKNG EDESAEVTLR RMLIMSGGDG YIDFRIGEEN EPELTGQSIR 420
  421 PRDMSHLIIW EVDAELPILS K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.69897
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle