YRC Public Data Repository - Protein Structure Prediction

Protein:	UXAA_ECOLI
Organism:	Escherichia coli
Length:	495 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UXAA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|218555659, gi... - gi\|218555659\|ref\|YP_002388572.1\| altronate hydrolase [Escherichia coli IAI1], gi\|218362427\|emb\|CAR00... gi\|218696795, gi... - gi\|218696795\|ref\|YP_002404462.1\| altronate hydrolase [Escherichia coli 55989], gi\|218353527\|emb\|CAU9... gi\|194418035, gi... - gi\|194433772\|ref\|ZP_03066047.1\| altronate dehydratase [Shigella dysenteriae 1012], gi\|194418035\|gb\|E... gi\|75187900, gi\|... - gi\|75187900\|ref\|ZP_00701167.1\| COG2721: Altronate dehydratase [Escherichia coli E24377A], gi\|1571560...	747.0	[0..1]	[495..1]
gi\|74313638, gi\|... - gi\|74313638\|ref\|YP_312057.1\| altronate hydrolase [Shigella sonnei Ss046], gi\|73857115\|gb\|AAZ89822.1\|...	747.0	[0..1]	[495..1]
gi\|26249680, gi\|... - gi\|26249680\|ref\|NP_755720.1\| Altronate hydrolase [Escherichia coli CFT073], gi\|26110108\|gb\|AAN82294.... gi\|218691394, gi... - gi\|218691394\|ref\|YP_002399606.1\| altronate hydrolase [Escherichia coli ED1a], gi\|218428958\|emb\|CAR09... gi\|227887816, gi... - gi\|227887816\|ref\|ZP_04005621.1\| altronate hydrolase [Escherichia coli 83972], gi\|227835212\|gb\|EEJ456... gi\|191172252, gi... - gi\|75240878\|ref\|ZP_00724776.1\| COG2721: Altronate dehydratase [Escherichia coli F11], gi\|191172252\|r...	747.0	[0..1]	[495..1]
gi\|218560175, gi... - gi\|218560175\|ref\|YP_002393088.1\| altronate hydrolase [Escherichia coli S88], gi\|218366944\|emb\|CAR047... gi\|117625399, gi... - gi\|117625399\|ref\|YP_858722.1\| altronate hydrolase UxaA [Escherichia coli APEC O1], gi\|115514523\|gb\|A... gi\|91074094, gi\|... - gi\|91212520\|ref\|YP_542506.1\| altronate hydrolase [Escherichia coli UTI89], gi\|91074094\|gb\|ABE08975.1... gi\|237706148, gi... - gi\|237706148\|ref\|ZP_04536629.1\| altronate hydrolase UxaA [Escherichia sp. 3_2_53FAA], gi\|226899188\|g...	746.0	[0..1]	[495..1]
gi\|110643335, gi... - gi\|110643335\|ref\|YP_671065.1\| altronate hydrolase [Escherichia coli 536], gi\|110344927\|gb\|ABG71164.1... gi\|170681891, gi... - gi\|170681891\|ref\|YP_001745361.1\| altronate dehydratase [Escherichia coli SMS-3-5], gi\|170519609\|gb\|A...	746.0	[0..1]	[495..1]
gi\|75239340, gi\|... - gi\|75239340\|ref\|ZP_00723311.1\| COG2721: Altronate dehydratase [Escherichia coli E110019], gi\|1930673...	746.0	[0..1]	[495..1]
gi\|75229993, gi\|... - gi\|75229993\|ref\|ZP_00716506.1\| COG2721: Altronate dehydratase [Escherichia coli B7A], gi\|191166849\|r...	746.0	[0..1]	[495..1]
gi\|110616521, gi... - gi\|110806973\|ref\|YP_690493.1\| altronate hydrolase [Shigella flexneri 5 str. 8401], gi\|110616521\|gb\|A...	746.0	[0..1]	[495..1]
gi\|187430525, gi... - gi\|75176067\|ref\|ZP_00696235.1\| COG2721: Altronate dehydratase [Shigella boydii BS512], gi\|187733533\|...	745.0	[0..1]	[495..1]
gi\|188493331, gi... - gi\|75513304\|ref\|ZP_00735728.1\| COG2721: Altronate dehydratase [Escherichia coli 53638], gi\|188493331...	744.0	[0..1]	[495..1]

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Predicted Domain #1

Region A:
Residues: [1-88]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQYIKIHALD NVAVALADLA EGTEVSVDNQ TVTLRQDVAR GHKFALTDIA KGANVIKYGL  60
   61 PIGYALADIA AGVHVHAHNT RTNLSDLD

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	12.455932
Match:	PF08666.3
Description:	No description for PF08666.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.725	0.298	hydro-lyase activity	b.1.1	Immunoglobulin
View	Download	0.684	0.081	lyase activity	b.1.18	E set domains
View	Download	0.556	0.021	hydro-lyase activity	d.15.1	Ubiquitin-like
View	Download	0.877	0.006	hydro-lyase activity	d.15.2	CAD & PB1 domains
View	Download	0.553	N/A	N/A	d.15.2	CAD & PB1 domains

Predicted Domain #2

Region A:
Residues: [89-151]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYRYQPDFQD LPAQAADREV QIYRRANGDV GVRNELWILP TVGCVNGIAR QIQNRFLKET  60
   61 NNA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [152-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGTDGVFLFS HTYGCSQLGD DHINTRTMLQ NMVRHPNAGA VLVIGLGCEN NQVAAFRETL  60
   61 GDIDPERVHF MICQQQDDEI EAGIEHLHQL YNVMRNDKRE PGKLSELKFG LECGGSDGLS 120
  121 GITANPMLGR FSDYVIANGG TTVLTEVPEM FGAEQLLMDH CRDEATFEKL VTMVNDFKQY 180
  181 FIAHDQPIYE NPSP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [346-423]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNKAGGITTL EDKSLGCTQK AGSSVVVDVL RYGERLKTPG LNLLSAPGND AVATSALAGA  60
   61 GCHMVLFSTG RGTPYGGF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [424-495]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPTVKIATNS ELAAKKKHWI DFDAGQLIHG KAMPQLLEEF IDTIVEFANG KQTCNERNDF  60
   61 RELAIFKSGV TL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits