YRC Public Data Repository - Protein Structure Prediction

Protein:	S100A7
Organism:	Homo sapiens
Length:	100 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for S100A7.

Description	E-value	Query Range	Subject Range
gi\|50748592 - gi\|50748592\|ref\|XP_421316.1\| PREDICTED: similar to calmodulin 1; Calmodulin 1 (phosphorylase kinase,...	112.0	[0..2]	[78..589]
gi\|109016674 - gi\|109016674\|ref\|XP_001108718.1\| PREDICTED: similar to Protein S100-A11 (S100 calcium-binding protei...	112.0	[0..1]	[97..439]
gi\|73961682 - gi\|73961682\|ref\|XP_547585.2\| PREDICTED: similar to Calgranulin B (Migration inhibitory factor-relate...	109.0	[0..2]	[99..227]
gi\|94471603 - gi\|94471603\|gb\|ABF21069.1\| mitochondrial calcium sensor cameleon 4mtD3cpv [synthetic construct]	107.0	[0..2]	[78..440]
gi\|76612513 - gi\|76612513\|ref\|XP_595126.2\| PREDICTED: similar to Calgizzarin (S100 calcium-binding protein A11) (S...	106.0	[0..1]	[97..85]
gi\|34811430, gi\|... - gi\|34811430\|pdb\|1NSH\|B Chain B, Solution Structure Of Rabbit Apo-S100a11 (19 Models), gi\|34811429\|pd...	104.0	[0..2]	[97..3]
gi\|114677917 - gi\|114677917\|ref\|XP_512771.2\| PREDICTED: similar to calmodulin [Pan troglodytes]	103.0	[0..2]	[78..200]

Back

Predicted Domain #1

Region A:
Residues: [1-100]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNTQAERSII GMIDMFHKYT RRDDKIDKPS LLTMMKENFP NFLSACDKKG TNYLADVFEK  60
   61 KDKNEDKKID FSEFLSLLGD IATDYHKQSH GAAPCSGGSQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.0
Match:	1psrA
Description:	Calcyclin (S100)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.97708242402885	bayes_pls_golite062009
calcium ion binding	1.40919295397643	bayes_pls_golite062009
ion binding	1.36376383271837	bayes_pls_golite062009
cation binding	1.34827363853601	bayes_pls_golite062009
metal ion binding	1.34827363853601	bayes_pls_golite062009
calcium-dependent protein binding	1.21038989135406	bayes_pls_golite062009
protein binding	1.06263369232144	bayes_pls_golite062009
transporter activity	0.751717017963896	bayes_pls_golite062009
transmembrane transporter activity	0.573179802647827	bayes_pls_golite062009
substrate-specific transporter activity	0.373421951050343	bayes_pls_golite062009
transcription regulator activity	0.188216209019877	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.15563262257885	bayes_pls_golite062009
structural constituent of muscle	0.14454341648094	bayes_pls_golite062009
signal transducer activity	0.0523340836750263	bayes_pls_golite062009
molecular transducer activity	0.0523340836750263	bayes_pls_golite062009
cytoskeletal protein binding	0.0128369896420697	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: