YRC Public Data Repository - Protein Structure Prediction

Protein:	RUVC_RALSO
Organism:	Ralstonia solanacearum
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RUVC_RALSO.

Description	E-value	Query Range	Subject Range
RUVC_CUPPJ - Crossover junction endodeoxyribonuclease RuvC OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 11...	249.0	[0..1]	[181..1]
RUVC_CUPMC - Crossover junction endodeoxyribonuclease RuvC OS=Cupriavidus metallidurans (strain ATCC 43123 / DSM ...	247.0	[0..1]	[181..1]
RUVC_CUPNH - Crossover junction endodeoxyribonuclease RuvC OS=Cupriavidus necator (strain ATCC 17699 / H16 / DSM ...	247.0	[0..1]	[181..1]
gi\|83724003, gi\|... - gi\|83749325\|ref\|ZP_00946322.1\| Crossover junction endodeoxyribonuclease ruvC [Ralstonia solanacearum... gi\|207742354, gi... - gi\|207742354\|ref\|YP_002258746.1\| crossover junction endodeoxyribonuclease ruvc (hollidayjunction nuc...	247.0	[0..1]	[181..1]
gi\|76811143, gi\|... - gi\|76811143\|ref\|YP_334776.1\| Holliday junction resolvase [Burkholderia pseudomallei 1710b], gi\|76580...	244.0	[0..1]	[181..96]
gi\|83652274, gi\|... - gi\|83718449\|ref\|YP_441796.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia thailandens...	243.0	[0..1]	[181..133]
RUVC_BURXL - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia xenovorans (strain LB400) GN=ruvC PE=3...	240.0	[0..1]	[181..1]
gi\|85065512 - gi\|85065512\|ref\|ZP_01026365.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... RUVC_BURPS - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia pseudomallei GN=ruvC PE=3 SV=1 gi\|100266016, gi... - gi\|87316585\|ref\|ZP_01097600.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... RUVC_BURMA - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia mallei GN=ruvC PE=3 SV=1 RUVC_BURP1 - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia pseudomallei (strain 1710b) GN=ruvC PE... RUVC_BURM7 - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia mallei (strain NCTC 10247) GN=ruvC PE=... gi\|237504363, gi... - gi\|237813763\|ref\|YP_002898214.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia pseudom... gi\|194505341, gi... - gi\|99912862\|ref\|ZP_01319560.1\| hypothetical protein Bpse1_03001127 [Burkholderia pseudomallei 1655],... gi\|225929592, gi... - gi\|226198409\|ref\|ZP_03793978.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia pseudoma... gi\|83621502, gi\|... - gi\|83621502\|ref\|ZP_00931911.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|238523445, gi... - gi\|67642317\|ref\|ZP_00441075.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia mallei GB... gi\|67754028, gi\|... - gi\|67754028\|ref\|ZP_00492946.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|67759074, gi\|... - gi\|67759074\|ref\|ZP_00497819.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|161371421, gi... - gi\|90291258\|ref\|ZP_01210889.1\| hypothetical protein Bpse17_02004080 [Burkholderia pseudomallei 1710a... gi\|84523894 - gi\|84523894\|ref\|ZP_01011030.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|167847252 - gi\|167847252\|ref\|ZP_02472760.1\| Holliday junction resolvase [Burkholderia pseudomallei B7210] RUVC_BURP0 - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia pseudomallei (strain 1106a) GN=ruvC PE... gi\|167895839 - gi\|167895839\|ref\|ZP_02483241.1\| Holliday junction resolvase [Burkholderia pseudomallei 7894] gi\|167817362 - gi\|167817362\|ref\|ZP_02449042.1\| Holliday junction resolvase [Burkholderia pseudomallei 91] gi\|167825770 - gi\|167825770\|ref\|ZP_02457241.1\| Holliday junction resolvase [Burkholderia pseudomallei 9] gi\|100235729, gi... - gi\|83680051\|ref\|ZP_00941759.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|167920441 - gi\|167920441\|ref\|ZP_02507532.1\| Holliday junction resolvase [Burkholderia pseudomallei BCC215] gi\|67637902, gi\|... - gi\|67637902\|ref\|ZP_00436840.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|217420409, gi... - gi\|217420409\|ref\|ZP_03451914.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia pseudoma... gi\|161357100, gi... - gi\|82538690\|ref\|ZP_00897683.1\| hypothetical protein Bpse110_02000385 [Burkholderia pseudomallei 1106... gi\|167904230 - gi\|167904230\|ref\|ZP_02491435.1\| Holliday junction resolvase [Burkholderia pseudomallei NCTC 13177] gi\|194527848, gi... - gi\|83626748\|ref\|ZP_00936972.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... gi\|167912489 - gi\|167912489\|ref\|ZP_02499580.1\| Holliday junction resolvase [Burkholderia pseudomallei 112] gi\|167721173 - gi\|167721173\|ref\|ZP_02404409.1\| Holliday junction resolvase [Burkholderia pseudomallei DM98] gi\|167740149 - gi\|167740149\|ref\|ZP_02412923.1\| Holliday junction resolvase [Burkholderia pseudomallei 14] gi\|243063560, gi... - gi\|243063560\|gb\|EES45746.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia mallei PRL-2... gi\|134248435, gi... - gi\|134280428\|ref\|ZP_01767139.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia pseudoma... RUVC_BURPS - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia pseudomallei (strain K96243) GN=ruvC P... RUVC_BURMA - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia mallei (strain ATCC 23344) GN=ruvC PE=...	239.0	[0..1]	[181..1]
RUVC_BURP6 - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia pseudomallei (strain 668) GN=ruvC PE=3...	237.0	[0..1]	[181..1]
RUVC_BURCA - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia cenocepacia (strain AU 1054) GN=ruvC P... gi\|194557292, gi... - gi\|84356807\|ref\|ZP_00981642.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Burkhol... RUVC_BURCH - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia cenocepacia (strain HI2424) GN=ruvC PE... RUVC_BURCJ - Crossover junction endodeoxyribonuclease RuvC OS=Burkholderia cenocepacia (strain ATCC BAA-245 / DSM...	233.0	[0..1]	[181..1]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRILGIDPGL RTTGFGVLER HGHQLVYVAS GTIKSDGNAD LPSRLKTLYD GVSELVRTYR  60
   61 PDCASIEKVF VNVNPQSTLL LGQARGAVIC GLMSGNLPVF EYTALQLKQA VVGYGRANKD 120
  121 QVQDMVVRLL NLEGRPGTDA ADALGVAICH AHGGETLAAM AGLAPQLARK GLRVRRGRLV 180
  181 G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.0
Match:	1hjrA
Description:	RuvC resolvase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
exonuclease activity	2.2254764376369	bayes_pls_golite062009
nuclease activity	2.17358374135419	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.75713164321634	bayes_pls_golite062009
hydrolase activity	1.52863974928789	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1.19309748194103	bayes_pls_golite062009
deoxyribonuclease activity	1.1219517187744	bayes_pls_golite062009
ribonuclease activity	0.901073799675851	bayes_pls_golite062009
DNA polymerase activity	0.717600245625866	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.568273228950698	bayes_pls_golite062009
endonuclease activity	0.527074808116937	bayes_pls_golite062009
exodeoxyribonuclease activity	0.278838342302102	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.261428436029202	bayes_pls_golite062009
binding	0.122249780594036	bayes_pls_golite062009
3'-5' exonuclease activity	0.115254148049348	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: