YRC Public Data Repository - Protein Structure Prediction

Protein:	RFBC_ECOLI
Organism:	Escherichia coli
Length:	185 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFBC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|237704492, gi... - gi\|237704492\|ref\|ZP_04534973.1\| RmlC [Escherichia sp. 3_2_53FAA], gi\|226900858\|gb\|EEH87117.1\| RmlC [... gi\|115513358, gi... - gi\|117624234\|ref\|YP_853147.1\| putative dTDP-4-dehydrorhamnose 3,5-epimerase [Escherichia coli APEC O...	290.0	[0..1]	[179..1]
gi\|46451854 - gi\|46451854\|gb\|AAS98029.1\| RmlC [Shigella boydii]	289.0	[0..1]	[176..1]
gi\|73809580 - gi\|73809580\|gb\|AAZ85706.1\| dTDP-6-deoxy-D-glucose-3,5 epimerase [Escherichia coli]	286.0	[0..1]	[178..1]
gi\|9957823 - gi\|9957823\|gb\|AAG09505.1\|AF279616_4 dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica]	285.0	[0..1]	[175..1]
RFBC_SALTY - dTDP-4-dehydrorhamnose 3,5-epimerase OS=Salmonella typhimurium GN=rfbC PE=1 SV=1 lcl\|NC_016856.1_... - [gene=rfbC] [protein=dTDP-4-deoxyrhamnose 3,5 epimerase] [protein_id=YP_005238129.1] [location=compl... RFBC_SALTY, RMLC... - dTDP-4-dehydrorhamnose 3,5-epimerase OS=Salmonella typhimurium GN=rfbC PE=1 SV=1, dTDP-4-dehydrorham... RMLC_SALTY - dTDP-4-dehydrorhamnose 3,5-epimerase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)... gi\|581655 - gi\|581655\|emb\|CAA40118.1\| rmlC [Salmonella enterica]	285.0	[0..1]	[178..2]
gi\|29136904, gi\|... - gi\|29141278\|ref\|NP_804620.1\| dTDP-4-dehydrorhamnose 3,5-epimerase [Salmonella enterica subsp. enteri... gi\|16761026 - gi\|16761026\|ref\|NP_456643.1\| dTDP-4-dehydrorhamnose 3,5-epimerase [Salmonella enterica subsp. enteri... gi\|25292478, gi\|... - gi\|25292478\|pir\|\|AC0767 dTDP-4-dehydrorhamnose 3,5-epimerase [imported] - Salmonella enterica subsp....	284.0	[0..1]	[178..2]
gi\|67158229, gi\|... - gi\|67158229\|ref\|ZP_00419279.1\| dTDP-4-dehydrorhamnose 3,5-epimerase [Azotobacter vinelandii AvOP], r... gi\|67084963, gi\|... - gi\|67158229\|ref\|ZP_00419279.1\| dTDP-4-dehydrorhamnose 3,5-epimerase [Azotobacter vinelandii AvOP], g...	283.0	[0..1]	[181..1]
gi\|82543416, gi\|... - gi\|82543416\|ref\|YP_407363.1\| dTDP-4-dehydrorhamnose 3,5-epimerase [Shigella boydii Sb227], gi\|812448... gi\|167410112 - gi\|167410112\|gb\|ABZ79716.1\| RmlC [Escherichia coli] gi\|16611726 - gi\|16611726\|gb\|AAL27313.1\|AF402312_5 dTDP-6-deoxy-D-glucose-3,5 epimerase [Shigella boydii]	283.0	[0..1]	[182..1]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVIRTEIED VLILEPRVFG DDRGFFYESF NQSAFEHILG YPVSFVQDNH SRSSKNVLRG  60
   61 LHFQRGEYAQ DKLVRCTHGA VFDVAVDIRP NSVSFGKWVG VLLSADNKQQ LWIPKGFAHG 120
  121 FLVLSDIAEF QYKTTNYYHP ESDCGICWND ERIAIDWPQT SGLILSPKDE RLFTLDELIR 180
  181 LKLIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.39794
Match:	1dzrA
Description:	dTDP-4-dehydrorhamnose 3,5-epimerase RmlC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dTDP-4-dehydrorhamnose 3,5-epimerase activity	2.99216880710047	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.79850768705664	bayes_pls_golite062009
catalytic activity	0.77242843392921	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.33927425209029	bayes_pls_golite062009
isomerase activity	0.02840080734269	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: