YRC Public Data Repository - Protein Structure Prediction

Protein:	RECG_ECOLI
Organism:	Escherichia coli
Length:	693 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RECG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|15804193, gi\|... - gi\|15804193\|ref\|NP_290232.1\| DNA helicase, resolution of Holliday junctions, branch migration [Esche... gi\|25290826 - gi\|25290826\|pir\|\|H86041 hypothetical protein recG [imported] - Escherichia coli (strain O157:H7, su...	604.0	[0..1]	[693..12]
gi\|191167788, gi... - gi\|75229043\|ref\|ZP_00715627.1\| COG1200: RecG-like helicase [Escherichia coli B7A], gi\|191167788\|ref\|...	602.0	[0..1]	[693..1]
gi\|83571439, gi\|... - gi\|83571439\|ref\|ZP_00922879.1\| COG1200: RecG-like helicase [Shigella dysenteriae 1012], gi\|194431101...	602.0	[0..1]	[693..1]
gi\|110807670, gi... - gi\|110807670\|ref\|YP_691190.1\| ATP-dependent DNA helicase RecG [Shigella flexneri 5 str. 8401], gi\|11... gi\|56480396, gi\|... - gi\|56480396\|ref\|NP_709432.2\| ATP-dependent DNA helicase RecG [Shigella flexneri 2a str. 301], gi\|563... gi\|30043333, gi\|... - gi\|30065072\|ref\|NP_839243.1\| ATP-dependent DNA helicase RecG [Shigella flexneri 2a str. 2457T], gi\|3...	602.0	[0..1]	[693..1]
gi\|157155919, gi... - gi\|75188410\|ref\|ZP_00701677.1\| COG1200: RecG-like helicase [Escherichia coli E24377A], gi\|157155919\|...	602.0	[0..1]	[693..1]
gi\|189002582, gi... - gi\|189002582\|gb\|EDU71568.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4076], ... gi\|168772379, gi... - gi\|187771588\|gb\|EDU35432.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4196], ... gi\|168766073, gi... - gi\|189364763\|gb\|EDU83182.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4486], ... gi\|254795607, gi... - gi\|254795607\|ref\|YP_003080444.1\| ATP-dependent DNA helicase [Escherichia coli O157:H7 str. TW14359],... gi\|189369873, gi... - gi\|189369873\|gb\|EDU88289.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4501], ... gi\|208809627, gi... - gi\|208809627\|ref\|ZP_03251964.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC420... gi\|195936213 - gi\|195936213\|ref\|ZP_03081595.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC402... gi\|189378859, gi... - gi\|189378859\|gb\|EDU97275.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC508], g... gi\|168785529, gi... - gi\|189374240\|gb\|EDU92656.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC869], g... gi\|168753477, gi... - gi\|189358845\|gb\|EDU77264.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4401], ... gi\|168748697, gi... - gi\|188016894\|gb\|EDU55016.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4113], ... gi\|161367493 - gi\|161367493\|ref\|NP_290232.2\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 EDL933] gi\|82546079, gi\|... - gi\|82546079\|ref\|YP_410026.1\| ATP-dependent DNA helicase RecG [Shigella boydii Sb227], gi\|81247490\|gb... RECG_ECO57 - ATP-dependent DNA helicase RecG OS=Escherichia coli O157:H7 GN=recG PE=3 SV=1 gi\|25290820, gi\|... - pir\|\|G91194 DNA helicase RecG [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)... gi\|15833781, gi\|... - gi\|15833781\|ref\|NP_312554.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. Sakai], ... gi\|217325846, gi... - gi\|217325846\|ref\|ZP_03441930.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. TW145... gi\|209397244, gi... - gi\|209397244\|ref\|YP_002273132.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC41... gi\|208820291, gi... - gi\|208820291\|ref\|ZP_03260611.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC404... gi\|208735701, gi... - gi\|208814424\|ref\|ZP_03255753.1\| ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC404...	602.0	[0..1]	[693..1]
gi\|73857590, gi\|... - gi\|74314113\|ref\|YP_312532.1\| ATP-dependent DNA helicase RecG [Shigella sonnei Ss046], gi\|73857590\|gb...	601.0	[0..1]	[693..1]
gi\|290502 - gi\|290502\|gb\|AAA62005.1\| DNA recombinase	600.0	[0..1]	[693..1]
gi\|110643893, gi... - gi\|110643893\|ref\|YP_671623.1\| ATP-dependent DNA helicase RecG [Escherichia coli 536], gi\|110345485\|g... gi\|75242569, gi\|... - gi\|75242569\|ref\|ZP_00726313.1\| COG1200: RecG-like helicase [Escherichia coli F11], gi\|191170316\|ref\|...	600.0	[0..1]	[693..1]
gi\|187732822, gi... - gi\|75179689\|ref\|ZP_00699676.1\| COG1200: RecG-like helicase [Shigella boydii BS512], gi\|187732822\|ref...	600.0	[0..1]	[693..1]

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Predicted Domain #1

Region A:
Residues: [1-693]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGRLLDAVP LSSLTGVGAA LSNKLAKINL HTVQDLLLHL PLRYEDRTHL YPIGELLPGV  60
   61 YATVEGEVLN CNISFGGRRM MTCQISDGSG ILTMRFFNFS AAMKNSLAAG RRVLAYGEAK 120
  121 RGKYGAEMIH PEYRVQGDLS TPELQETLTP VYPTTEGVKQ ATLRKLTDQA LDLLDTCAIE 180
  181 ELLPPELSQG MMTLPEALRT LHRPPPTLQL SDLETGQHPA QRRLILEELL AHNLSMLALR 240
  241 AGAQRFHAQP LSANDTLKNK LLAALPFKPT GAQARVVAEI ERDMALDVPM MRLVQGDVGS 300
  301 GKTLVAALAA LRAIAHGKQV ALMAPTELLA EQHANNFRNW FAPLGIEVGW LAGKQKGKAR 360
  361 LAQQEAIASG QVQMIVGTHA IFQEQVQFNG LALVIIDEQH RFGVHQRLAL WEKGQQQGFH 420
  421 PHQLIMTATP IPRTLAMTAY ADLDTSVIDE LPPGRTPVTT VAIPDTRRTD IIDRVHHACI 480
  481 TEGRQAYWVC TLIEESELLE AQAAEATWEE LKLALPELNV GLVHGRMKPA EKQAVMASFK 540
  541 QGELHLLVAT TVIEVGVDVP NASLMIIENP ERLGLAQLHQ LRGRVGRGAV ASHCVLLYKT 600
  601 PLSKTAQIRL QVLRDSNDGF VIAQKDLEIR GPGELLGTRQ TGNAEFKVAD LLRDQAMIPE 660
  661 VQRLARHIHE RYPQQAKALI ERWMPETERY SNA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.0
Match:	1gm5A
Description:	RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009
pyrophosphatase activity	1.16998111465319	bayes_pls_golite062009
binding	0.712909626033412	bayes_pls_golite062009
helicase activity	0.00674361801283974	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: