YRC Public Data Repository - Protein Structure Prediction

Protein:	QOR_ECOLI
Organism:	Escherichia coli
Length:	327 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QOR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|86134306, gi\|... - gi\|86134306\|ref\|ZP_01052888.1\| zinc-binding dehydrogenase [Polaribacter sp. MED152], gi\|85821169\|gb\|...	323.0	[0..2]	[325..12]
gi\|28872343, gi\|... - gi\|28872343\|ref\|NP_794962.1\| oxidoreductase, zinc-binding [Pseudomonas syringae pv. tomato str. DC30... tr\|Q87UR5\|Q87UR5... - Oxidoreductase, zinc-binding protein OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_523...	309.0	[0..2]	[325..1]
gi\|71733591, gi\|... - gi\|71733591\|ref\|YP_272602.1\| quinone oxidoreductase [Pseudomonas syringae pv. phaseolicola 1448A], g...	306.0	[0..2]	[325..1]
gi\|63254289, gi\|... - gi\|66043582\|ref\|YP_233423.1\| zinc-containing alcohol dehydrogenase superfamily protein [Pseudomonas ...	303.0	[0..2]	[325..1]
gi\|77967831, gi\|... - gi\|78067086\|ref\|YP_369855.1\| zinc-containing alcohol dehydrogenase superfamily protein [Burkholderia...	303.0	[0..1]	[327..1]
gi\|77385669, gi\|... - gi\|77461666\|ref\|YP_351173.1\| zinc-containing alcohol dehydrogenase superfamily protein [Pseudomonas ...	303.0	[0..2]	[325..1]
gi\|68347561, gi\|... - gi\|70733262\|ref\|YP_263035.1\| oxidoreductase, zinc-binding [Pseudomonas fluorescens Pf-5], gi\|6834756...	300.0	[0..2]	[325..1]
gi\|83851394, gi\|... - gi\|83945224\|ref\|ZP_00957573.1\| probable oxidoreductase protein [Oceanicaulis alexandrii HTCC2633], g...	300.0	[0..2]	[327..1]
gi\|94417709, gi\|... - gi\|94417709\|ref\|ZP_01297526.1\| hypothetical protein PaerP_01000487 [Pseudomonas aeruginosa PA7], gi\|...	300.0	[0..2]	[325..1]
gi\|84317897, gi\|... - gi\|84317897\|ref\|ZP_00966332.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct... gi\|116053381, gi... - gi\|32044610\|ref\|ZP_00141711.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct... gi\|107104336 - gi\|107104336\|ref\|ZP_01368254.1\| hypothetical protein PaerPA_01005411 [Pseudomonas aeruginosa PACS2]	299.0	[0..2]	[325..1]

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Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATRIEFHKH GGPEVLQAVE FTPADPAENE IQVENKAIGI NFIDTYIRSG LYPPPSLPSG  60
   61 LGTEAAGIVS KVGSGVKHIK AGDRVVYAQS ALGAYSSVHN IIADKAAILP AAISFEQAAA 120
  121 SFLKGLTVYY LLRKTYEIKP DEQFLFHAAA GGVGLIACQW AKALGAKLIG TVGTAQKAQS 180
  181 ALKAGAWQVI NYREEDLVER LKEITGGKKV RVVYDSVGRD TWERSLDCLQ RRGLMVSFGN 240
  241 SSGAVTGVNL GILNQKGSLY VTRPSLQGYI TTREELTEAS NELFSLIASG VIKVDVAEQQ 300
  301 KYPLKDAQRA HEILESRATQ GSSLLIP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.09691
Match:	1qorA
Description:	Quinone oxidoreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alcohol dehydrogenase (NAD) activity	2.94416173750168	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	2.26153457113968	bayes_pls_golite062009
oxidoreductase activity	1.98266850665386	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
retinol dehydrogenase activity	1.04497968922284	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
nucleic acid binding	0.980245559401213	bayes_pls_golite062009
DNA binding	0.940078857029005	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.903132922944611	bayes_pls_golite062009
transcription regulator activity	0.854100257756792	bayes_pls_golite062009
RNA binding	0.843556706364142	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.8131556272556	bayes_pls_golite062009
chaperone binding	0.593082758130032	bayes_pls_golite062009
protein binding	0.507836099271263	bayes_pls_golite062009
transcription factor activity	0.35056694435192	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: