YRC Public Data Repository - Protein Structure Prediction

Protein:	PYRF_VIBCH
Organism:	Vibrio cholerae
Length:	231 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRF_VIBCH.

Description	E-value	Query Range	Subject Range
PYRF_VIBC3 - Orotidine 5'-phosphate decarboxylase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical O...	235.0	[0..1]	[231..1]
gi\|69156212, gi\|... - gi\|91793113\|ref\|YP_562764.1\| orotidine 5'-phosphate decarboxylase [Shewanella denitrificans OS217], ...	231.0	[0..1]	[231..1]
gi\|151937856, gi... - gi\|75856152\|ref\|ZP_00763785.1\| COG0284: Orotidine-5'-phosphate decarboxylase [Vibrio sp. Ex25], gi\|2...	227.0	[0..1]	[230..1]
gi\|91188854, gi\|... - gi\|91226891\|ref\|ZP_01261488.1\| orotidine 5'-phosphate decarboxylase [Vibrio alginolyticus 12G01], gi...	227.0	[0..1]	[230..1]
gi\|238794724, gi... - gi\|77977460\|ref\|ZP_00832908.1\| COG0284: Orotidine-5'-phosphate decarboxylase [Yersinia intermedia AT...	227.0	[0..4]	[230..15]
PYRF_PASMU - Orotidine 5'-phosphate decarboxylase OS=Pasteurella multocida GN=pyrF PE=3 SV=1 PYRF_PASMU - Orotidine 5'-phosphate decarboxylase OS=Pasteurella multocida (strain Pm70) GN=pyrF PE=3 SV=1	226.0	[0..4]	[230..3]
PYRF_VIBPA - Orotidine 5'-phosphate decarboxylase OS=Vibrio parahaemolyticus GN=pyrF PE=3 SV=1 PYRF_VIBPA - Orotidine 5'-phosphate decarboxylase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)...	226.0	[0..1]	[230..1]
PYRF_VIBF1 - Orotidine 5'-phosphate decarboxylase OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=pyrF PE=3 SV... PYRF_VIBFM - Orotidine 5'-phosphate decarboxylase OS=Vibrio fischeri (strain MJ11) GN=pyrF PE=3 SV=1	225.0	[0..1]	[226..1]
gi\|86148760, gi\|... - gi\|86148760\|ref\|ZP_01067032.1\| orotidine 5'-phosphate decarboxylase [Vibrio sp. MED222], gi\|85833457...	225.0	[0..1]	[226..1]
PYRF_HAEIN - Orotidine 5'-phosphate decarboxylase OS=Haemophilus influenzae GN=pyrF PE=3 SV=1 gi\|46133576 - gi\|46133576\|ref\|ZP_00157409.2\| COG0284: Orotidine-5'-phosphate decarboxylase [Haemophilus influenzae... PYRF_HAEIN - Orotidine 5'-phosphate decarboxylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20... gi\|145274277, gi... - gi\|145641116\|ref\|ZP_01796697.1\| orotidine 5'-phosphate decarboxylase [Haemophilus influenzae R3021],... gi\|145641116 - gi\|145641116\|ref\|ZP_01796697.1\| orotidine 5'-phosphate decarboxylase [Haemophilus influenzae R3021] gi\|145639205, gi... - gi\|145639205\|ref\|ZP_01794812.1\| orotidine 5'-phosphate decarboxylase [Haemophilus influenzae PittII]...	224.0	[0..4]	[230..3]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDPKVIVAL DYDNLADALA FVDKIDPSTC RLKVGKEMFT LFGPDFVREL HKRGFSVFLD  60
   61 LKFHDIPNTC SKAVKAAAEL GVWMVNVHAS GGERMMAASR EILEPYGKER PLLIGVTVLT 120
  121 SMESADLQGI GILSAPQDHV LRLATLTKNA GLDGVVCSAQ EASLLKQHLG REFKLVTPGI 180
  181 RPAGSEQGDQ RRIMTPAQAI ASGSDYLVIG RPITQAAHPE VVLEEINSSL V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.69897
Match:	1eixA
Description:	Orotidine 5'-monophosphate decarboxylase (OMP decarboxylase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
orotidine-5'-phosphate decarboxylase activity	2.87717797280068	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
ribulose-phosphate 3-epimerase activity	0.982517927791965	bayes_pls_golite062009
carboxy-lyase activity	0.83446736141993	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.108467338662618	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: