YRC Public Data Repository - Protein Structure Prediction

Protein:	PTHY_CANLF
Organism:	Canis lupus familiaris
Length:	115 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTHY_CANLF.

Description	E-value	Query Range	Subject Range
gi\|119588900 - gi\|119588900\|gb\|EAW68494.1\| parathyroid hormone, isoform CRA_a [Homo sapiens] gi\|55635601 - gi\|55635601\|ref\|XP_521846.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	174.0	[0..1]	[115..33]
PTHY_FELCA - Parathyroid hormone OS=Felis catus GN=PTH PE=3 SV=1	171.0	[0..1]	[115..1]
PTHY_BOVIN - Parathyroid hormone OS=Bos taurus GN=PTH PE=1 SV=1	168.0	[0..1]	[115..1]
gi\|2144646 - pir\|\|PTPG parathyroid hormone precursor - pig PTHY_PIG - Parathyroid hormone OS=Sus scrofa GN=PTH PE=1 SV=1	166.0	[0..1]	[115..1]
PTHY_HORSE - Parathyroid hormone OS=Equus caballus GN=PTH PE=3 SV=1	165.0	[0..1]	[115..1]
gi\|114636278 - gi\|114636278\|ref\|XP_001171819.1\| PREDICTED: hypothetical protein isoform 1 [Pan troglodytes] gi\|208968649 - gi\|208968649\|dbj\|BAG74163.1\| parathyroid hormone [synthetic construct] PTH - parathyroid hormone	165.0	[0..1]	[115..1]
CCDS7812.1_1 - null gi\|109107219 - gi\|109107219\|ref\|XP_001094024.1\| PREDICTED: parathyroid hormone [Macaca mulatta] PTHY_MACFA - Parathyroid hormone OS=Macaca fascicularis GN=PTH PE=3 SV=1	164.0	[0..1]	[115..1]
PTHY_RAT - Parathyroid hormone OS=Rattus norvegicus GN=Pth PE=2 SV=1	158.0	[0..1]	[115..1]
gi\|4092930, gi\|6... - gi\|74216176\|dbj\|BAE23743.1\| unnamed protein product [Mus musculus], gi\|68534186\|gb\|AAH99456.1\| Parat...	156.0	[0..1]	[115..1]

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Predicted Domain #1

Region A:
Residues: [1-115]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSAKDMVKV MIVMFAICFL AKSDGKPVKK RSVSEIQFMH NLGKHLSSME RVEWLRKKLQ  60
   61 DVHNFVALGA PIAHRDGSSQ RPLKKEDNVL VESYQKSLGE ADKADVDVLT KAKSQ

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	67.522879
Match:	PF01279.8
Description:	No description for PF01279.8 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.793	0.029	lactation	a.66.1	Transducin (alpha subunit), insertion domain
View	Download	0.597	N/A	N/A	a.66.1	Transducin (alpha subunit), insertion domain
View	Download	0.590	N/A	N/A	a.48.1	N-terminal domain of cbl (N-cbl)
View	Download	0.560	N/A	N/A	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.546	N/A	N/A	a.8.2	Plasmid maintenance system epsilon/zeta, antidote epsilon subunit

Predicted functions:

Term	Confidence	Notes
G-protein-coupled receptor binding	1.81931356445777	bayes_pls_golite062009
protein binding	1.66071060222784	bayes_pls_golite062009
receptor binding	1.65652135485729	bayes_pls_golite062009
binding	1.43721720719603	bayes_pls_golite062009
guanyl nucleotide binding	0.603253776263003	bayes_pls_golite062009
guanyl ribonucleotide binding	0.60311172579467	bayes_pls_golite062009
GTP binding	0.589045888056193	bayes_pls_golite062009
catalytic activity	0.396811738319255	bayes_pls_golite062009
GTPase activity	0.109049656997511	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: