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View Structure Prediction Details

Protein: PLDB_ECOLI
Organism: Escherichia coli
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLDB_ECOLI.

Description E-value Query
Range
Subject
Range
gi|117626084, gi... - gi|117626084|ref|YP_859407.1| lysophospholipase L2 [Escherichia coli APEC O1], gi|115515208|gb|ABJ03...
gi|226903006, gi... - gi|237702835|ref|ZP_04533316.1| lysophospholipase L2 [Escherichia sp. 3_2_53FAA], gi|226903006|gb|EE...
gi|218367657, gi... - gi|218560888|ref|YP_002393801.1| lysophospholipase L2 [Escherichia coli S88], gi|218367657|emb|CAR05...
gi|218692101, gi... - gi|218692101|ref|YP_002400313.1| lysophospholipase L2 [Escherichia coli ED1a], gi|218429665|emb|CAR1...
gi|218701482, gi... - gi|218701482|ref|YP_002409111.1| lysophospholipase L2 [Escherichia coli IAI39], gi|218371468|emb|CAR...
gi|91074925, gi|... - gi|91213351|ref|YP_543337.1| lysophospholipase L2 [Escherichia coli UTI89], gi|91074925|gb|ABE09806....
195.0 [0..1] [340..1]
gi|194417714, gi... - gi|83569338|ref|ZP_00920793.1| COG2267: Lysophospholipase [Shigella dysenteriae 1012], gi|194434056|...
194.0 [0..1] [340..1]
gi|81243142, gi|... - gi|82778994|ref|YP_405343.1| lysophospholipase L2 [Shigella dysenteriae Sd197], gi|81243142|gb|ABB63...
194.0 [0..1] [340..1]
gi|168763955, gi... - gi|189365982|gb|EDU84398.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4501], gi|16876395...
gi|189358883, gi... - gi|189358883|gb|EDU77302.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4401], gi|16875372...
gi|187768848, gi... - gi|187768848|gb|EDU32692.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4196], gi|16877561...
gi|189362549, gi... - gi|189362549|gb|EDU80968.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4486], gi|16876811...
gi|168750358, gi... - gi|188015412|gb|EDU53534.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4113], gi|16875035...
gi|254795823, gi... - gi|254795823|ref|YP_003080660.1| lysophospholipase L(2) [Escherichia coli O157:H7 str. TW14359], gi|...
gi|13364231, gi|... - gi|15834009|ref|NP_312782.1| lysophospholipase L2 [Escherichia coli O157:H7 str. Sakai], gi|13364231...
gi|13364231, gi|... - gi|15834009|ref|NP_312782.1| lysophospholipase L(2) [Escherichia coli O157:H7], gi|13364231|dbj|BAB3...
gi|209753138, gi... - pir||A86070 lysophospholipase L(2) [imported] - Escherichia coli (strain O157:H7, substrain EDL933)...
gi|217325822, gi... - gi|217325822|ref|ZP_03441906.1| lysophospholipase L2 [Escherichia coli O157:H7 str. TW14588], gi|217...
gi|15804417, gi|... - gi|15804417|ref|NP_290457.1| lysophospholipase L2 [Escherichia coli O157:H7 EDL933], gi|12518702|gb|...
gi|208734335, gi... - gi|208813058|ref|ZP_03254387.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4045], gi|2087...
gi|208807887, gi... - gi|208807887|ref|ZP_03250224.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4206], gi|2087...
gi|209398086, gi... - gi|209398086|ref|YP_002273344.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4115], gi|209...
gi|208819329, gi... - gi|208819329|ref|ZP_03259649.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4042], gi|2087...
gi|168786668, gi... - gi|189373207|gb|EDU91623.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC869], gi|168786668...
gi|189001504, gi... - gi|189001504|gb|EDU70490.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4076], gi|16878072...
gi|195938117 - gi|195938117|ref|ZP_03083499.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC4024]
gi|168801106, gi... - gi|189376703|gb|EDU95119.1| lysophospholipase L2 [Escherichia coli O157:H7 str. EC508], gi|168801106...
194.0 [0..1] [340..1]
gi|75197708, gi|... - gi|75197708|ref|ZP_00707778.1| COG2267: Lysophospholipase [Escherichia coli HS], gi|157163301|ref|YP...
gi|226838728, gi... - gi|254039037|ref|ZP_04873088.1| lysophospholipase L2 [Escherichia sp. 1_1_43], gi|226838728|gb|EEH70...
193.0 [0..1] [340..1]
gi|148224 - gi|148224|gb|AAA67621.1| lysophospholipase L2 [Escherichia coli]
gi|148224|gb|AAA... - lysophospholipase L2 [Escherichia coli]
192.0 [0..1] [340..1]
gi|24115121, gi|... - gi|24115121|ref|NP_709631.1| lysophospholipase L2 [Shigella flexneri 2a str. 301], gi|24054391|gb|AA...
gi|30043138, gi|... - gi|30064878|ref|NP_839049.1| lysophospholipase L2 [Shigella flexneri 2a str. 2457T], gi|30043138|gb|...
192.0 [0..1] [340..1]
gi|78066438, gi|... - gi|78066438|ref|YP_369207.1| Alpha/beta hydrolase [Burkholderia sp. 383], gi|77967183|gb|ABB08563.1|...
192.0 [0..34] [323..3]
gi|62182430, gi|... - gi|62182430|ref|YP_218847.1| lysophospholipase L2 [Salmonella enterica subsp. enterica serovar Chole...
lcl|NC_016856.1_... - [gene=pldB] [protein=lysophospholipase L2] [protein_id=YP_005240223.1] [location=4179455..4180567]
189.0 [0..1] [336..33]
gi|238717560, gi... - gi|77960563|ref|ZP_00824429.1| COG2267: Lysophospholipase [Yersinia mollaretii ATCC 43969], gi|23879...
189.0 [0..5] [339..7]

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Predicted Domain #1
Region A:
Residues: [1-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQQQKDWET RENAFAAFTM GPLTDFWRQR DEAEFTGVDD IPVRFVRFRA QHHDRVVVIC  60
   61 PGRIESYVKY AELAYDLFHL GFDVLIIDHR GQGRSGRLLA DPHLGHVNRF NDYVDDLAAF 120
  121 WQQEVQPGPW RKRYILAHSM GGAISTLFLQ RHPGVCDAIA LTAPMFGIVI RMPSFMARQI 180
  181 LNWAEAHPRF RDGYAIGTGR WRALPFAINV LTHSRQRYRR NLRFYADDPT IRVGGPTYHW 240
  241 VRESILAGEQ VLAGAGDDAT PTLLLQAEEE RVVDNRMHDR FCELRTAAGH PVEGGRPLVI 300
  301 KGAYHEILFE KDAMRSVALH AIVDFFNRHN SPSGNRSTEV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1s8oA
Description: Human soluble Epoxide Hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.76673721118052 bayes_pls_golite062009
carboxylesterase activity 0.73967567655491 bayes_pls_golite062009
lipase activity 0.51002916472898 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.112278861211575 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle