YRC Public Data Repository - Protein Structure Prediction

Protein:	NUSB_MYCTU
Organism:	Mycobacterium tuberculosis
Length:	156 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUSB_MYCTU.

Description	E-value	Query Range	Subject Range
gi\|49080752 - gi\|49080752\|gb\|AAT50054.1\| PA4052 [synthetic construct]	151.0	[0..4]	[148..15]
gi\|94417012, gi\|... - gi\|94417012\|ref\|ZP_01296834.1\| hypothetical protein PaerP_01001208 [Pseudomonas aeruginosa PA7], gi\|...	150.0	[0..4]	[148..15]
NUSB_PSEAE - N utilization substance protein B homolog OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C /... gi\|46164642, gi\|... - gi\|46164642\|ref\|ZP_00205138.1\| COG0781: Transcription termination factor [Pseudomonas aeruginosa UCB... gi\|84325185, gi\|... - gi\|84325185\|ref\|ZP_00973225.1\| COG0781: Transcription termination factor [Pseudomonas aeruginosa 219... gi\|107103566 - gi\|107103566\|ref\|ZP_01367484.1\| hypothetical protein PaerPA_01004636 [Pseudomonas aeruginosa PACS2] gi\|218889667, gi... - gi\|218889667\|ref\|YP_002438531.1\| transcription antitermination protein NusB [Pseudomonas aeruginosa ... NUSB_PSEAE - N utilization substance protein B homolog OS=Pseudomonas aeruginosa GN=nusB PE=3 SV=1	150.0	[0..4]	[148..15]
gi\|126168872, gi... - gi\|84319131\|ref\|ZP_00967534.1\| COG0781: Transcription termination factor [Pseudomonas aeruginosa C37...	149.0	[0..4]	[148..15]
gi\|51856176, gi\|... - gi\|51892487\|ref\|YP_075178.1\| hypothetical protein STH1349 [Symbiobacterium thermophilum IAM 14863], ...	149.0	[0..6]	[154..5]
NUSB_PSE14 - N utilization substance protein B homolog OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A /...	147.0	[0..2]	[152..19]
NUSB_HISS2 - N utilization substance protein B homolog OS=Histophilus somni (strain 2336) GN=nusB PE=3 SV=1	145.0	[0..1]	[139..1]
NUSB_MYCBO - N utilization substance protein B homolog OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) G... gi\|215431478 - gi\|215431478\|ref\|ZP_03429397.1\| transcription antitermination protein NusB [Mycobacterium tuberculos... NUSB_MYCBP - N utilization substance protein B homolog OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) GN=nu... gi\|215427926 - gi\|215427926\|ref\|ZP_03425845.1\| transcription antitermination protein NusB [Mycobacterium tuberculos... NUSB_MYCBO - N utilization substance protein B homolog OS=Mycobacterium bovis GN=nusB PE=3 SV=1 NUSB_MYCBT - N utilization substance protein B homolog OS=Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 3573... gi\|219558534 - gi\|219558534\|ref\|ZP_03537610.1\| transcription antitermination protein NusB [Mycobacterium tuberculos...	144.0	[0..1]	[156..1]
gi\|88925497, gi\|... - gi\|88944826\|ref\|ZP_01148049.1\| Fmu, rRNA SAM-dependent methyltransferase:NusB antitermination factor...	144.0	[0..12]	[156..5]
gi\|67085734, gi\|... - gi\|67157057\|ref\|ZP_00418419.1\| Antitermination protein NusB [Azotobacter vinelandii AvOP], gi\|670857... gi\|67157057, gi\|... - gi\|67157057\|ref\|ZP_00418419.1\| Antitermination protein NusB [Azotobacter vinelandii AvOP], ref\|ZP_00...	144.0	[0..4]	[146..15]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDRKPVRGR HQARKRAVAL LFEAEVRGIS AAEVVDTRAA LAEAKPDIAR LHPYTAAVAR  60
   61 GVSEHAAHID DLITAHLRGW TLDRLPAVDR AILRVSVWEL LHAADVPEPV VVDEAVQLAK 120
  121 ELSTDDSPGF VNGVLGQVML VTPQLRAAAQ AVRGGA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.39794
Match:	1eyvA
Description:	Antitermination factor NusB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription termination factor activity	7.08625510047476	bayes_pls_golite062009
transcription regulator activity	3.63525538465601	bayes_pls_golite062009
binding	0.569728786489819	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: