YRC Public Data Repository - Protein Structure Prediction

Protein:	NTF2_DEBHA
Organism:	Debaryomyces hansenii
Length:	124 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTF2_DEBHA.

Description	E-value	Query Range	Subject Range
NTF2_CANGA - Nuclear transport factor 2 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / ... NTF2_CANGA - Nuclear transport factor 2 OS=Candida glabrata GN=NTF2 PE=3 SV=1	161.0	[0..1]	[124..1]
gi\|223640932, gi... - gi\|241949743\|ref\|XP_002417594.1\| nuclear transport factor 2, putative [Candida dubliniensis CD36], g... NTF2_CANAX - Nuclear transport factor 2 OS=Candida albicans GN=NTF2 PE=3 SV=1	159.0	[0..1]	[124..1]
NTF2_ASHGO - Nuclear transport factor 2 OS=Ashbya gossypii GN=NTF2 PE=3 SV=1 NTF2_ASHGO - Nuclear transport factor 2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1...	157.0	[0..1]	[124..1]
NTF2_KLULA - Nuclear transport factor 2 OS=Kluyveromyces lactis GN=NTF2 PE=3 SV=1 NTF2_KLULA - Nuclear transport factor 2 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1...	157.0	[0..1]	[124..1]
ORFP:6054 - YER009W, Contig c425 25784-26161 gi\|190405570 - gi\|190405570\|gb\|EDV08837.1\| nuclear transport factor [Saccharomyces cerevisiae RM11-1a] NTF2_YEAST - Nuclear transport factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTF2 PE=1 SV=... NTF2 - Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to tr... gi\|151944717 - gi\|151944717\|gb\|EDN62976.1\| nuclear transport factor [Saccharomyces cerevisiae YJM789]	157.0	[0..1]	[124..1]
gi\|125562321 - gi\|125562321\|gb\|EAZ07769.1\| hypothetical protein OsI_30022 [Oryza sativa Indica Group] NTF2_ORYSA - Nuclear transport factor 2 (NTF-2) - Oryza sativa (Rice) NTF2_ORYSJ - Nuclear transport factor 2 OS=Oryza sativa subsp. japonica GN=NTF2 PE=2 SV=1	154.0	[0..3]	[123..1]
gi\|94403170, gi\|... - gi\|94404128\|ref\|XP_988895.1\| PREDICTED: similar to Nuclear transport factor 2 (NTF-2) [Mus musculus]...	152.0	[0..3]	[121..5]
gi\|50746525 - gi\|50746525\|ref\|XP_420536.1\| PREDICTED: similar to KIAA0660 protein [Gallus gallus]	149.0	[0..3]	[121..92]
gi\|25310685, gi\|... - gi\|9802547\|gb\|AAF99749.1\|AC004557_28 F17L21.10 [Arabidopsis thaliana], pir\|\|H86398 protein F17L21.10...	148.0	[0..3]	[124..1]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVDFNTVAS EFCNFYYQQF DSDRTQLGNL YREQSMLTFE TSQLQGAKDI VEKLVSLPFQ  60
   61 KVAHRISTLD AQPGSPNGDI LVMVTGELII DDEQNAQRYS QVFHLIPDGN SYYVFNDIFR 120
  121 LNYS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.0
Match:	1gy7A
Description:	Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.2858716221712	bayes_pls_golite062009
nucleocytoplasmic transporter activity	2.57260151088345	bayes_pls_golite062009
binding	2.32562999055027	bayes_pls_golite062009
protein transmembrane transporter activity	2.22367856601071	bayes_pls_golite062009
transporter activity	1.80701285041353	bayes_pls_golite062009
substrate-specific transporter activity	1.33804818542017	bayes_pls_golite062009
structural constituent of nuclear pore	1.30758304562723	bayes_pls_golite062009
protein binding	1.24260899146543	bayes_pls_golite062009
transmembrane transporter activity	1.22102896992563	bayes_pls_golite062009
Ran GTPase binding	1.18290069522408	bayes_pls_golite062009
RNA binding	1.05240446104847	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.890150150408175	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.79772386064313	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.79772386064313	bayes_pls_golite062009
nucleic acid binding	0.688410645367506	bayes_pls_golite062009
primary active transmembrane transporter activity	0.446562877324676	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.439519001457896	bayes_pls_golite062009
active transmembrane transporter activity	0.430285640125175	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: