YRC Public Data Repository - Protein Structure Prediction

Protein:	MTOX_ECOLI
Organism:	Escherichia coli
Length:	372 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTOX_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77974930 - gi\|77974930\|ref\|ZP_00830468.1\| COG0665: Glycine/D-amino acid oxidases (deaminating) [Yersinia freder...	234.0	[0..1]	[371..1]
gi\|88192000, gi\|... - gi\|93279954\|pdb\|2GB0\|B Chain B, Monomeric Sarcosine Oxidase: Structure Of A Covalently Flavinylated ... gi\|12084640, gi\|... - gi\|20664324\|pdb\|1L9F\|B Chain B, Monomeric Sarcosine Oxidase: Structure Of A Covalently Flavinylated ...	232.0	[0..3]	[370..4]
gi\|77979984, gi\|... - gi\|77979984\|ref\|ZP_00835399.1\| COG0665: Glycine/D-amino acid oxidases (deaminating) [Yersinia interm...	232.0	[0..1]	[371..1]
gi\|23200324, gi\|... - gi\|23200324\|pdb\|1L9D\|B Chain B, Role Of Histidine 269 In Catalysis By Monomeric Sarcosine Oxidase, g...	232.0	[0..3]	[370..4]
gi\|209773540, gi... - pir\|\|A85668 sarcosine oxidase-like protein [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|15801176, gi\|... - gi\|15801176\|ref\|NP_287193.1\| N-methyltryptophan oxidase [Escherichia coli O157:H7 EDL933], gi\|125145... MTOX_ECO5E - N-methyl-L-tryptophan oxidase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=solA PE=3 SV=1 gi\|217328434, gi... - gi\|217328434\|ref\|ZP_03444516.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. TW14588... gi\|195935448 - gi\|195935448\|ref\|ZP_03080830.1\| N-methyltryptophan oxidase [Escherichia coli O157:H7 str. EC4024] gi\|208726182, gi... - gi\|208806381\|ref\|ZP_03248718.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4206]... MTOX_ECO57 - N-methyl-L-tryptophan oxidase OS=Escherichia coli O157:H7 GN=solA PE=3 SV=1 gi\|208816140, gi... - gi\|208816140\|ref\|ZP_03257319.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4045]... gi\|208737863, gi... - gi\|208822378\|ref\|ZP_03262697.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4042]... gi\|187770406, gi... - gi\|187770406\|gb\|EDU34250.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4196], gi... gi\|168783589, gi... - gi\|188999076\|gb\|EDU68062.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4076], gi... gi\|168789994, gi... - gi\|189370469\|gb\|EDU88885.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC869], gi\|... gi\|168802004, gi... - gi\|189375946\|gb\|EDU94362.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC508], gi\|... gi\|168747167, gi... - gi\|188018049\|gb\|EDU56171.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4113], gi... gi\|254792441, gi... - gi\|254792441\|ref\|YP_003077278.1\| N-methyltryptophan oxidase, FAD-binding [Escherichia coli O157:H7 s... gi\|189354589, gi... - gi\|189354589\|gb\|EDU73008.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4401], gi... gi\|168764471, gi... - gi\|189365513\|gb\|EDU83929.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4501], gi... gi\|168767718, gi... - gi\|189363200\|gb\|EDU81619.1\| N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4486], gi... gi\|15830691, gi\|... - gi\|15830691\|ref\|NP_309464.1\| N-methyltryptophan oxidase [Escherichia coli O157:H7 str. Sakai], gi\|13...	231.0	[0..1]	[372..1]
gi\|75513503, gi\|... - gi\|75513503\|ref\|ZP_00735907.1\| COG0665: Glycine/D-amino acid oxidases (deaminating) [Escherichia col...	231.0	[0..1]	[372..1]
gi\|191168456, gi... - gi\|75228327\|ref\|ZP_00714977.1\| COG0665: Glycine/D-amino acid oxidases (deaminating) [Escherichia col... MTOX_ECO24 - N-methyl-L-tryptophan oxidase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=solA PE=3 SV=1	231.0	[0..1]	[372..1]
gi\|83570494, gi\|... - gi\|83570494\|ref\|ZP_00921938.1\| COG0665: Glycine/D-amino acid oxidases (deaminating) [Shigella dysent...	231.0	[0..1]	[372..1]

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Predicted Domain #1

Region A:
Residues: [1-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYDLIIIGS GSVGAAAGYY ATRAGLNVLM TDAHMPPHQH GSHHGDTRLI RHAYGEGEKY  60
   61 VPLVLRAQTL WDELSRHNEE DPIFVRSGVI NLGPADSTFL ANVAHSAEQW QLNVEKLDAQ 120
  121 GIMARWPEIR VPDNYIGLFE TDSGFLRSEL AIKTWIQLAK EAGCAQLFNC PVTAIRHDDD 180
  181 GVTIETADGE YQAKKAIVCA GTWVKDLLPE LPVQPVRKVF AWYQADGRYS VKNKFPAFTG 240
  241 ELPNGDQYYG FPAENDALKI GKHNGGQVIH SADERVPFAE VASDGSEAFP FLRNVLPGIG 300
  301 CCLYGAACTY DNSPDEDFII DTLPGHDNTL LITGLSGHGF KFASVLGEIA ADFAQDKKSD 360
  361 FDLTPFRLSR FQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.0
Match:	1el5A
Description:	Sarcosine oxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.61125987248836	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.07245967881566	bayes_pls_golite062009
catalytic activity	1.03127962968326	bayes_pls_golite062009
oxidoreductase activity	0.943208146517927	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.681230241795345	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	0.397770205910041	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: