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View Structure Prediction Details

Protein: mthl12-PA
Organism: Drosophila melanogaster
Length: 488 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mthl12-PA.

Description E-value Query
Range
Subject
Range
FBpp0297746, mth-PA - The gene methuselah is referred to in FlyBase by the symbol Dmel\mth (CG6936, FBgn0023000). It is a ...
264.0 [0..2] [483..4]

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Predicted Domain #1
Region A:
Residues: [1-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLWLKCFCT LIIVTIAKNS SAKIPHCKYD ETINISHFKR LNDAYIYEHF EIPANLTGEF  60
   61 DYKELMDGSK VPTEFPNLRG CICKVRPCIR ICCARKNILS NGECSDGVKN EIKLTMLDLT 120
  121 MQDILLTDPT LAELNMIPQY NSTELLILRE QFQPCDEIVS LKRDEYTILK DGSILLHTSA 180
  181 EILSNDQYCL YPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1fjrA
Description: Methuselah ectodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
G-protein coupled receptor activity 7.48253527316663 bayes_pls_golite062009
transmembrane receptor activity 5.76968261800439 bayes_pls_golite062009
receptor activity 5.47976284348283 bayes_pls_golite062009
signal transducer activity 4.51388461085202 bayes_pls_golite062009
molecular transducer activity 4.51388461085202 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [194-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYSDFPETIR IINRRCYRNV MPGIAQLSVI SVVGFILTLA VYLSVEKLRN LLGKCLICSL  60
   61 FSMFMEYFIW TMDYFRLLQS ICSAAGYMKY FFSMSSYLWF SVVSFHLWEL FTSLNRHEPQ 120
  121 YRFLIYNTFV WCTAAIPTVV IFSMNQMWEN DPGKSEWLPL VGYFGCSVKD WNSSSWFYSH 180
  181 IPIVILNSFN VIMFVLTAIY IWKVKKGVKS FAQHDERNTT CLEFNVQTYI QFVRLFLIMG 240
  241 ASWLLDQLTR LAEDSHLLLD TIVLNLTVYL NAAFGILIFV LLILKGSTFK MIMER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle