YRC Public Data Repository - Protein Structure Prediction

Protein:	MLTD_ECOLI
Organism:	Escherichia coli
Length:	452 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MLTD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|209745516, gi... - pir\|\|G85505 hypothetical protein dniR [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12512939, gi\|... - gi\|15799887\|ref\|NP_285899.1\| membrane-bound lytic murein transglycosylase D [Escherichia coli O157:H... gi\|13359663, gi\|... - gi\|15829461\|ref\|NP_308234.1\| cytochrome c552 [Escherichia coli O157:H7], gi\|13359663\|dbj\|BAB33630.1\|... gi\|13359663, gi\|... - gi\|15829461\|ref\|NP_308234.1\| membrane-bound lytic murein transglycosylase D [Escherichia coli O157:H... gi\|254590738, gi... - gi\|254791338\|ref\|YP_003076175.1\| membrane-bound lytic murein transglycosylase D [Escherichia coli O1... gi\|218368828, gi... - gi\|218698842\|ref\|YP_002406471.1\| membrane-bound lytic murein transglycosylase D [Escherichia coli IA...	321.0	[0..1]	[452..1]
gi\|81239745, gi\|... - gi\|82775597\|ref\|YP_401944.1\| membrane-bound lytic murein transglycosylase D [Shigella dysenteriae Sd...	321.0	[0..1]	[452..1]
gi\|75241728 - gi\|75241728\|ref\|ZP_00725565.1\| COG0741: Soluble lytic murein transglycosylase and related regulatory...	321.0	[0..1]	[452..1]
gi\|110640426, gi... - gi\|110640426\|ref\|YP_668154.1\| membrane-bound lytic murein transglycosylase D [Escherichia coli 536],...	320.0	[0..1]	[452..1]
gi\|81244215, gi\|... - gi\|82542804\|ref\|YP_406751.1\| membrane-bound lytic murein transglycosylase D [Shigella boydii Sb227],... gi\|187730415, gi... - gi\|75176775\|ref\|ZP_00696891.1\| COG0741: Soluble lytic murein transglycosylase and related regulatory...	319.0	[0..1]	[452..1]
gi\|110613806, gi... - gi\|110804258\|ref\|YP_687778.1\| membrane-bound lytic murein transglycosylase D [Shigella flexneri 5 st...	319.0	[0..1]	[452..1]
lcl\|NC_016856.1_... - [gene=dniR] [protein=membrane-bound lytic murein transglycosylase D] [protein_id=YP_005235928.1] [lo... gi\|25513833, gi\|... - gi\|25513833\|pir\|\|AB0534 membrane-bound lytic murein transglycosylase d precursor (EC 3.2.1.-) [impor... gi\|16759246 - gi\|16759246\|ref\|NP_454863.1\| membrane-bound lytic murein transglycosylase D [Salmonella enterica sub... gi\|205271372, gi... - gi\|205351591\|ref\|YP_002225392.1\| membrane-bound lytic murein transglycosylase D [Salmonella enterica... gi\|197363548, gi... - gi\|197363548\|ref\|YP_002143185.1\| membrane-bound lytic murein transglycosylase D [Salmonella enterica... gi\|16418759, gi\|... - gi\|16763643\|ref\|NP_459258.1\| membrane-bound lytic murein transglycosylase D [Salmonella typhimurium ... gi\|29142979, gi\|... - gi\|29142979\|ref\|NP_806321.1\| membrane-bound lytic murein transglycosylase D [Salmonella enterica sub... gi\|56414620, gi\|... - gi\|56414620\|ref\|YP_151695.1\| membrane-bound lytic murein transglycosylase D [Salmonella enterica sub... gi\|224466628, gi... - gi\|224582101\|ref\|YP_002635899.1\| membrane-bound lytic murein transglycosylase d precursor [Salmonell...	316.0	[0..1]	[452..1]
gi\|62178826, gi\|... - gi\|62178826\|ref\|YP_215243.1\| membrane-bound lytic murein transglycosylase D [Salmonella enterica sub...	314.0	[0..1]	[452..1]
gi\|56383176, gi\|... - gi\|56479625\|ref\|NP_706152.2\| membrane-bound lytic murein transglycosylase D [Shigella flexneri 2a st... gi\|30061763, gi\|... - gi\|30061763\|ref\|NP_835934.1\| membrane-bound lytic murein transglycosylase D [Shigella flexneri 2a st...	314.0	[0..1]	[452..1]
gi\|75856800, gi\|... - gi\|75856800\|ref\|ZP_00764423.1\| COG0741: Soluble lytic murein transglycosylase and related regulatory...	282.0	[0..1]	[446..1]

Back

Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAKAILLAS VLLVGCQSTG NVQQHAQSLS AAGQGEAAKF TSQARWMDDG TSIAPDGDLW  60
   61 AFIGDELKMG IPENDRIREQ KQKYLRNKSY LHDVTLRAEP YMYWIAGQVK KRNMPMELVL 120
  121 LPIVESAFDP HATSGANAAG IWQIIPSTGR NYGLKQTRNY DARRDVVAST TAALNMMQRL 180
  181 NKMFDGDWLL TVAAYNSGEG RVMKAIKTNK ARGKSTDFWS LPLPQETKQY VPKMLALSDI 240
  241 LKNSKRYGVR LPTTDESRAL ARVHLSSP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.0
Match:	1qsaA
Description:	70 KDa soluble lytic transglycosylase (SLT70), superhelical domain; 70 kDa soluble lytic transglycosylase, SLT70
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
penicillin binding	2.64957480679626	bayes_pls_golite062009
catalytic activity	1.95328415115451	bayes_pls_golite062009
lysozyme activity	1.83799209924951	bayes_pls_golite062009
drug binding	1.54697929389118	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	1.16054683174437	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	1.07226857049823	bayes_pls_golite062009
hydrolase activity	0.677491712259	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.45061419828567	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [269-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEMAKVADMA GISVSKLKTF NAGVKGSTLG ASGPQYVMVP KKHADQLRES LASGEIAAVQ  60
   61 STLVADNTPL NSRVYTVRSG DTLSSIASRL GVSTKDLQQW NKLRGSKLKP GQSLTIG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.238	0.940	cell wall macromolecule catabolic process	d.2.1	Lysozyme-like

Predicted Domain #3

Region A:
Residues: [386-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGSSAQRLAN NSDSITYRVR KGDSLSSIAK RHGVNIKDVM RWNSDTANLQ PGDKLTLFVK  60
   61 NNNMPDS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.98
Match:	2djpA
Description:	No description for 2djpA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: