YRC Public Data Repository - Protein Structure Prediction

Protein:	MENC_ECOLI
Organism:	Escherichia coli
Length:	320 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MENC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|89085503, gi\|... - gi\|89099756\|ref\|ZP_01172629.1\| hypothetical protein B14911_21643 [Bacillus sp. NRRL B-14911], gi\|890...	250.0	[0..1]	[319..3]
AEEP_BACSU - L-Ala-D/L-Glu epimerase OS=Bacillus subtilis GN=ykfB PE=1 SV=1 AEEP_BACSU - L-Ala-D/L-Glu epimerase OS=Bacillus subtilis (strain 168) GN=ykfB PE=1 SV=1 gi\|221313484 - gi\|221313484\|ref\|ZP_03595289.1\| hypothetical protein BsubsN3_07137 [Bacillus subtilis subsp. subtili... gi\|221318406 - gi\|221318406\|ref\|ZP_03599700.1\| hypothetical protein BsubsJ_07071 [Bacillus subtilis subsp. subtilis... gi\|221322680 - gi\|221322680\|ref\|ZP_03603974.1\| hypothetical protein BsubsS_07182 [Bacillus subtilis subsp. subtilis...	248.0	[0..1]	[319..3]
gi\|52079796, gi\|... - gi\|52785166\|ref\|YP_090995.1\| YkfB [Bacillus licheniformis ATCC 14580], gi\|52347668\|gb\|AAU40302.1\| Yk...	247.0	[0..1]	[319..3]
gi\|150388312, gi... - gi\|77684669\|ref\|ZP_00800093.1\| Mandelate racemase/muconate lactonizing enzyme [Alkaliphilus metallir...	240.0	[0..1]	[318..3]
gi\|71483050 - gi\|71483050\|gb\|AAZ32484.1\| L-alanine-DL-glutamate epimerase-like [uncultured euryarchaeote Alv-FOS1]	236.0	[0..1]	[319..3]
gi\|106894816, gi... - gi\|158319963\|ref\|YP_001512470.1\| mandelate racemase/muconate lactonizing protein [Alkaliphilus oreml...	236.0	[0..1]	[318..3]
gi\|19712800, gi\|... - gi\|19712800\|gb\|AAL93701.1\| O-succinylbenzoate-CoA synthase [Fusobacterium nucleatum subsp. nucleatum...	230.0	[0..1]	[319..15]

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Predicted Domain #1

Region A:
Residues: [1-320]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSAQVYRWQ IPMDAGVVLR DRRLKTRDGL YVCLREGERE GWGEISPLPG FSQETWEEAQ  60
   61 SVLLAWVNNW LAGDCELPQM PSVAFGVSCA LAELTDTLPQ AANYRAAPLC NGDPDDLILK 120
  121 LADMPGEKVA KVKVGLYEAV RDGMVVNLLL EAIPDLHLRL DANRAWTPLK GQQFAKYVNP 180
  181 DYRDRIAFLE EPCKTRDDSR AFARETGIAI AWDESLREPD FAFVAEEGVR AVVIKPTLTG 240
  241 SLEKVREQVQ AAHALGLTAV ISSSIESSLG LTQLARIAAW LTPDTIPGLD TLDLMQAQQV 300
  301 RRWPGSTLPV VEVDALERLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.30103
Match:	1fhuA
Description:	O-succinylbenzoate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydro-lyase activity	1.37262309948483	bayes_pls_golite062009
catalytic activity	0.904956784158091	bayes_pls_golite062009
lyase activity	0.649994293495516	bayes_pls_golite062009
carbon-oxygen lyase activity	0.500416702127569	bayes_pls_golite062009
phosphopyruvate hydratase activity	0.135147261429977	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: