YRC Public Data Repository - Protein Structure Prediction

Protein:	LIPB_BRUME
Organism:	Brucella melitensis
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIPB_BRUME.

Description	E-value	Query Range	Subject Range
LIPB_BRUSU - Octanoyltransferase OS=Brucella suis biovar 1 (strain 1330) GN=lipB PE=3 SV=1 gi\|161620651, gi... - gi\|161620651\|ref\|YP_001594537.1\| lipoyltransferase [Brucella canis ATCC 23365], gi\|161337462\|gb\|ABX6... LIPB_BRUSU - Octanoyltransferase OS=Brucella suis GN=lipB PE=3 SV=1 gi\|254702964 - gi\|254702964\|ref\|ZP_05164792.1\| lipoyltransferase [Brucella suis bv. 3 str. 686]	339.0	[0..1]	[264..1]
LIPB_BRUAB - Octanoyltransferase OS=Brucella abortus biovar 1 (strain 9-941) GN=lipB PE=3 SV=1 gi\|254732282 - gi\|254732282\|ref\|ZP_05190860.1\| lipoyltransferase [Brucella abortus bv. 4 str. 292] LIPB_BRUA2 - Octanoyltransferase OS=Brucella abortus (strain 2308) GN=lipB PE=3 SV=1 gi\|237787915, gi... - gi\|237817102\|ref\|ZP_04596094.1\| lipoate-protein ligase B [Brucella abortus str. 2308 A], gi\|23778791... LIPB_BRUAB - Octanoyltransferase OS=Brucella abortus GN=lipB PE=3 SV=1 gi\|254698835 - gi\|254698835\|ref\|ZP_05160663.1\| lipoyltransferase [Brucella abortus bv. 2 str. 86/8/59]	339.0	[0..1]	[264..1]
LIPB_CHESB - Octanoyltransferase OS=Chelativorans sp. (strain BNC1) GN=lipB PE=3 SV=1	282.0	[0..40]	[262..12]
LIPB_RHIME - Octanoyltransferase OS=Rhizobium meliloti GN=lipB PE=3 SV=1 LIPB_RHIME - Octanoyltransferase OS=Rhizobium meliloti (strain 1021) GN=lipB PE=3 SV=1	281.0	[0..21]	[264..7]
LIPB_SINMW - Octanoyltransferase OS=Sinorhizobium medicae (strain WSM419) GN=lipB PE=3 SV=1	278.0	[0..22]	[264..8]
gi\|25349504 - pir\|\|D97548 lipoate-protein ligase b (lipoate biosynthesis protein b) [imported] - Agrobacterium tum... LIPB_AGRFC - Octanoyltransferase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=lipB PE=3 SV=1	270.0	[0..35]	[264..34]
gi\|90419573, gi\|... - gi\|90419573\|ref\|ZP_01227483.1\| lipoate-protein ligase B [Aurantimonas sp. SI85-9A1], gi\|90336510\|gb\|... gi\|90419573, gi\|... - gi\|90419573\|ref\|ZP_01227483.1\| lipoate-protein ligase B [Aurantimonas sp. SI85-9A1], gi\|90336510\|gb\|...	270.0	[0..16]	[259..1]
LIPB_RHILO - Octanoyltransferase OS=Rhizobium loti GN=lipB PE=3 SV=1 LIPB_RHILO - Octanoyltransferase OS=Rhizobium loti (strain MAFF303099) GN=lipB PE=3 SV=1	268.0	[0..27]	[259..2]
LIPB_MAGSA - Octanoyltransferase OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) GN=lipB PE=3 SV=1	267.0	[0..42]	[259..1]
gi\|114539685, gi... - gi\|114704900\|ref\|ZP_01437808.1\| lipoyltransferase [Fulvimarina pelagi HTCC2506], gi\|114539685\|gb\|EAU...	267.0	[0..16]	[261..1]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTGKLRQKP PYAAIMTNSP VTPSTETQQP KRYARFLPQE ADAPPVEWLI AEGLTDYEEA  60
   61 LAFMEARVQA IREGTASELV WLVEHPPLYT AGTSANAEDL LTPDRFPVFN TGRGGEYTYH 120
  121 GPGQRVAYVM LDLKRRREDV RAFVASLEQW IIETLAAFNI KGERREDRVG VWVVRPEKPR 180
  181 LADGSMCEDK IAAIGIRLRR WVSFHGIAIN VEPDLSHYGG IVPCGISEHG VTSLVDLGLP 240
  241 VTMGDVDVAL GKAFESVFGP RQTK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.69897
Match:	1w66A
Description:	Title withheld
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminoacyl-tRNA ligase activity	4.025601351766	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	4.02412423650651	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	4.02412423650651	bayes_pls_golite062009
ligase activity	3.51191116674556	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	0.91205340076545	bayes_pls_golite062009
binding	0.521863822270226	bayes_pls_golite062009
serine-tRNA ligase activity	0.410923263101581	bayes_pls_golite062009
glycine-tRNA ligase activity	0.25613083187245	bayes_pls_golite062009
ATP binding	0.18403217430648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.145955341735342	bayes_pls_golite062009
threonine-tRNA ligase activity	0.133891091298639	bayes_pls_golite062009
adenyl nucleotide binding	0.127823774098159	bayes_pls_golite062009
protein binding	0.0101455326199739	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: