YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|148660170, gi...
Organism:	Mycobacterium tuberculosis H37Ra
Length:	1402 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|148660170, gi....

Description	E-value	Query Range	Subject Range
gi\|15839791, gi\|... - gi\|15839791\|ref\|NP_334828.1\| polyketide synthase [Mycobacterium tuberculosis CDC1551], gi\|13879921\|g...	1007.0	[0..1]	[1401..1]
gi\|31616732, gi\|... - gi\|31616732\|emb\|CAD60099.1\| polyketide synthase type 1 [Anabaena circinalis 90], gi\|31505494\|gb\|AAO6...	960.0	[0..3]	[1240..1975]
gi\|23126916 - gi\|23126916\|ref\|ZP_00108797.1\| COG3321: Polyketide synthase modules and related proteins [Nostoc pun...	955.0	[0..4]	[1213..925]
gi\|50082958 - gi\|50082958\|gb\|AAT70105.1\| CurJ [Lyngbya majuscula]	946.0	[0..100]	[1226..29]
gi\|9955391 - gi\|9955391\|dbj\|BAB12210.1\| polyketide synthase [Microcystis aeruginosa]	945.0	[0..6]	[1240..2008]
gi\|48892275, gi\|... - gi\|71673901\|ref\|ZP_00671649.1\| Beta-ketoacyl synthase:Thioesterase:Acyl transferase region:Phosphopa...	943.0	[0..106]	[1393..35]
gi\|28976140 - gi\|28976140\|gb\|AAO64405.1\| NdaD [Nodularia spumigena]	941.0	[0..3]	[1240..1983]
gi\|6007552 - gi\|6007552\|gb\|AAF00959.1\| McyD [Microcystis aeruginosa PCC 7806] gi\|6007552 - gi\|6007552\|gb\|AAF00959.1\|AF183408_7 McyD [Microcystis aeruginosa PCC 7806]	940.0	[0..6]	[1240..2008]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDGSVTADK LQKWFREYLS THIECHPNEV SLDVPIRDLG LKSIDVLAIP GDLGDRFGFC  60
   61 IPDLAVWDNP SANDLIDSLL NQRSADSLRE SHGH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.39794
Match:	2ju1A
Description:	No description for 2ju1A was found.

Predicted Domain #2

Region A:
Residues: [95-978]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADRNTQGRGS INEPVAVIGV GCRFPGDIDG PERLWDFLTE KKCAITAYPD RGFTNAGTFA  60
   61 ESGGFLKDVA GFDNRFFDIP PDEALRMDPQ QRLLLEVSWE ALEHAGIIPE SLRLSRTGVF 120
  121 VGVSSTDYVR LVSASAQQKS TIWDNTGGSS SIIANRISYF LDIQGPSIVI DTACSSSLVA 180
  181 VHLACRSLST WDCDIALVGG TNVLISPEPW GGFREAGILS QTGCCHAFDK SADGMVRGEG 240
  241 CGVIVLQRLS DARLEGRRIL AILTGSAVNQ DGKSNGIMAP NPSAQIGVLE NACKSARVDP 300
  301 LEIGYVEAHG TGTSLGDRIE AHALGMVFGR KRPGSGPLMI GSIKPNIGHL EGAAGIAGLI 360
  361 KAVLMVERGS LLPSGGFTEP NPAIPFTELG LRVVDELQEW PVVAGRPRRA GVSSFGFGGT 420
  421 NAHVIVEEAG SVGADTVSGR ADVGGSGGGV VAWVISGKTA SALAAQAGRL GRYVRARPAL 480
  481 DVVDVGYSLV STRSVFDHRA VVVGQTRDEL LAGLAGVVAG RPEAGVVCGV GKPAGKTAFV 540
  541 FAGQGSQWLG MGSELYAAYP VFAEALDAVV DELDRHLRYP LRDVIWGHDQ DLLNTTEFAQ 600
  601 PALFAVEVAL YRLLMSWGVR PGLVLGHSVG ELAAAHVAGA LCLPDAAMLV AARGRLMQAL 660
  661 PAGGAMFAVQ AREDEVAPML GHDVSIAAVN GPASVVISGA HDAVSAIADR LRGQGRRVHR 720
  721 LAVSHAFHSA LMEPMIAEFT AVAAELSVGL PTIPVISNVT GQLVADDFAS ADYWARHIRA 780
  781 VVRFGDSVRS AHCAGASRFI EVGPGGGLTS LIEASLADAQ IVSVPTLRKD RPEPVSVMTA 840
  841 AAQGFVSGMG LDWASVFSGY RPKRVELPTY AFQHQKFWLA PAPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2hg4A
Description:	No description for 2hg4A was found.

Predicted Domain #3

Region A:
Residues: [979-1098]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSDPTAAGQI GASDGGAELL ASSGFAARLA GRSADEQLAA AIEVVCEHAA AVLGRDGAAG  60
   61 LDAGQAFADS GFNSLSAVEL RNRLTAVTAV TLPATAIFDH PTPTELAQYL ITQIDGHGSS 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.87
Match:	2ju1A
Description:	No description for 2ju1A was found.

Predicted Domain #4

Region A:
Residues: [1099-1402]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAAANPAER IDALTDLFLQ ACDAGRDADG WKMVALASNT RERMSSPVRN NVSKNVALLA  60
   61 DGISDVVVIC IPTLTVLSDQ REYRDIANAM TGRHSVYSLT LPGFDSSDAL PQNADMIVET 120
  121 VSNAIIDVVG GSCRFVLSGY SSGGVLAYAL CSHLSVKHQR NPLGVALIDT YLPSQIANPS 180
  181 MNEGFSPNDT GKGLSREVIR VARMLNRLTA TRLTAAATYA AIFQAWEPGR SMAPVLNIVA 240
  241 KDRIATVENL REERINRWRT AAAEAAYSVA EVPGDHFGMM STSSEAIATE IHDWISGLVR 300
  301 GPHR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.045757
Match:	2h7xA
Description:	No description for 2h7xA was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.264183693934251	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: