YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|147923740, gi...
Organism:	Streptococcus pneumoniae SP3-BS71
Length:	139 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|147923740, gi....

Description	E-value	Query Range	Subject Range
RUVX_STRA3 - Putative Holliday junction resolvase OS=Streptococcus agalactiae serotype III GN=gbs2044 PE=3 SV=1 RUVX_STRA1 - Putative Holliday junction resolvase OS=Streptococcus agalactiae serotype Ia GN=SAK_2029 PE=3 SV=2 YQGF_STRA1 - Putative pre-16S rRNA nuclease OS=Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / C... RUVX_STRA5 - Putative Holliday junction resolvase OS=Streptococcus agalactiae serotype V GN=SAG2090 PE=3 SV=1 YQGF_STRA3 - Putative pre-16S rRNA nuclease OS=Streptococcus agalactiae serotype III (strain NEM316) GN=gbs2044 P... YQGF_STRA5 - Putative pre-16S rRNA nuclease OS=Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/...	195.0	[0..1]	[139..1]
YQGF_STRMU - Putative pre-16S rRNA nuclease OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) GN=SM... RUVX_STRMU - Putative Holliday junction resolvase OS=Streptococcus mutans GN=SMU_2078c PE=3 SV=1	195.0	[0..1]	[139..1]
YQGF_STRPD - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M2 (strain MGAS10270) GN=MGAS10270...	194.0	[0..1]	[139..1]
YQGF_STRP6 - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS1039... YQGF_STRPG - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M5 (strain Manfredo) GN=SpyM51755 ... YQGF_STRPQ - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M3 (strain SSI-1) GN=SPs1795 PE=3 ... YQGF_STRP8 - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M18 (strain MGAS8232) GN=spyM18_21... RUVX_STRP6 - Putative Holliday junction resolvase OS=Streptococcus pyogenes serotype M6 GN=M6_Spy1795 PE=3 SV=1 RUVX_STRP8 - Putative Holliday junction resolvase OS=Streptococcus pyogenes serotype M18 GN=spyM18_2171 PE=3 SV=1 YQGF_STRPB - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M12 (strain MGAS2096) GN=MGAS2096_... YQGF_STRPC - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M12 (strain MGAS9429) GN=MGAS9429_... YQGF_STRPF - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M4 (strain MGAS10750) GN=MGAS10750... YQGF_STRP3 - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)... RUVX_STRP3 - Putative Holliday junction resolvase OS=Streptococcus pyogenes serotype M3 GN=SpyM3_1797 PE=3 SV=1 RUVX_STRPM - Putative Holliday junction resolvase OS=Streptococcus pyogenes serotype M28 GN=M28_Spy1780 PE=3 SV=1 YQGF_STRPM - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M28 (strain MGAS6180) GN=M28_Spy17...	194.0	[0..1]	[139..1]
gi\|71911609, gi\|... - gi\|71911609\|ref\|YP_283159.1\| Holliday junction resolvase-like protein [Streptococcus pyogenes MGAS50... RUVX_STRPY - (Q99XP4) Putative Holliday junction resolvase (EC 3.1.-.-) gi\|15675863, gi\|... - gi\|15675863\|ref\|NP_270037.1\| Holliday junction resolvase-like protein [Streptococcus pyogenes M1 GAS... YQGF_STRP1 - Putative pre-16S rRNA nuclease OS=Streptococcus pyogenes serotype M1 GN=SPy_2113 PE=3 SV=1	194.0	[0..1]	[139..1]
gi\|55739831, gi\|... - gb\|AAV63472.1\| DNA recombination protein, putative [Streptococcus thermophilus CNRZ1066], gb\|AAV615... YQGF_STRT1 - Putative pre-16S rRNA nuclease OS=Streptococcus thermophilus (strain CNRZ 1066) GN=str1960 PE=3 SV=1 YQGF_STRT2 - Putative pre-16S rRNA nuclease OS=Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) GN=st...	194.0	[0..1]	[139..1]
YQGF_STRTD - Putative pre-16S rRNA nuclease OS=Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) GN=STER_1...	193.0	[0..1]	[139..1]
gi\|228747663, gi... - gi\|229013604\|ref\|ZP_04170735.1\| Holliday junction resolvase [Bacillus mycoides DSM 2048], gi\|2287476... gi\|228717234, gi... - gi\|229062082\|ref\|ZP_04199407.1\| Holliday junction resolvase [Bacillus cereus AH603], gi\|228717234\|gb... gi\|229032036, gi... - gi\|229032036\|ref\|ZP_04188019.1\| Holliday junction resolvase [Bacillus cereus AH1271], gi\|228729281\|g... gi\|228614358, gi... - gi\|229169130\|ref\|ZP_04296845.1\| Holliday junction resolvase [Bacillus cereus AH621], gi\|228614358\|gb... YQGF_BACWK - Putative pre-16S rRNA nuclease OS=Bacillus weihenstephanensis (strain KBAB4) GN=BcerKBAB4_4233 PE=3 ... gi\|228648251, gi... - gi\|229135209\|ref\|ZP_04264008.1\| Holliday junction resolvase [Bacillus cereus BDRD-ST196], gi\|2286482... gi\|229175060, gi... - gi\|229175060\|ref\|ZP_04302578.1\| Holliday junction resolvase [Bacillus cereus MM3], gi\|228608428\|gb\|E...	192.0	[0..1]	[138..1]
gi\|228974484, gi... - gi\|228974484\|ref\|ZP_04135051.1\| Holliday junction resolvase [Bacillus thuringiensis serovar thuringi... gi\|228799022, gi... - gi\|228960658\|ref\|ZP_04122303.1\| Holliday junction resolvase [Bacillus thuringiensis serovar pakistan... gi\|228987638, gi... - gi\|228987638\|ref\|ZP_04147752.1\| Holliday junction resolvase [Bacillus thuringiensis serovar tochigie... gi\|228981078, gi... - gi\|228981078\|ref\|ZP_04141379.1\| Holliday junction resolvase [Bacillus thuringiensis Bt407], gi\|22877... gi\|229081651, gi... - gi\|229081651\|ref\|ZP_04214146.1\| Holliday junction resolvase [Bacillus cereus Rock4-2], gi\|228701655\|... gi\|206969800, gi... - gi\|206969800\|ref\|ZP_03230754.1\| conserved hypothetical protein TIGR00250 [Bacillus cereus AH1134], g... gi\|229048094, gi... - gi\|229048094\|ref\|ZP_04193667.1\| Holliday junction resolvase [Bacillus cereus AH676], gi\|228723249\|gb... gi\|229192598, gi... - gi\|229192598\|ref\|ZP_04319559.1\| Holliday junction resolvase [Bacillus cereus ATCC 10876], gi\|2285909... gi\|228602807, gi... - gi\|229180662\|ref\|ZP_04308002.1\| Holliday junction resolvase [Bacillus cereus 172560W], gi\|228602807\|... gi\|228954671, gi... - gi\|228954671\|ref\|ZP_04116694.1\| Holliday junction resolvase [Bacillus thuringiensis serovar kurstaki... gi\|47556604, gi\|... - gi\|47566574\|ref\|ZP_00237396.1\| conserved hypothetical protein protein TIGR00250 [Bacillus cereus G92... gi\|228818110, gi... - gi\|228941554\|ref\|ZP_04104103.1\| Holliday junction resolvase [Bacillus thuringiensis serovar berliner...	192.0	[0..1]	[138..1]
gi\|228923138, gi... - gi\|228923138\|ref\|ZP_04086429.1\| Holliday junction resolvase [Bacillus thuringiensis serovar huazhong... gi\|229129667, gi... - gi\|229129667\|ref\|ZP_04258635.1\| Holliday junction resolvase [Bacillus cereus BDRD-Cer4], gi\|22865378... YQGF_BACC4 - Putative pre-16S rRNA nuclease OS=Bacillus cereus (strain B4264) GN=BCB4264_A4506 PE=3 SV=1 gi\|228636556, gi... - gi\|229146957\|ref\|ZP_04275321.1\| Holliday junction resolvase [Bacillus cereus BDRD-ST24], gi\|22863655... gi\|228711191, gi... - gi\|229071895\|ref\|ZP_04205106.1\| Holliday junction resolvase [Bacillus cereus F65185], gi\|228711191\|g... gi\|229111859, gi... - gi\|229111859\|ref\|ZP_04241405.1\| Holliday junction resolvase [Bacillus cereus Rock1-15], gi\|228671615... YQGF_BACCR - Putative pre-16S rRNA nuclease OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 1530... gi\|228630851, gi... - gi\|229152590\|ref\|ZP_04280779.1\| Holliday junction resolvase [Bacillus cereus m1550], gi\|228630851\|gb...	191.0	[0..1]	[138..1]

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Predicted Domain #1

Region A:
Residues: [1-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIMGLDVGS KTVGVAISDP LGFTAQGLEI IQINEEQGQF GFDRVKELVD TYKVERFVVG  60
   61 LPKNMNNTSG PRVEASQAYG AKLEEFFGLP VDYQDERLTT VAAERMLIEQ ADISRNKRKK 120
  121 VIDKLAAQLI LQNYLDRKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.522879
Match:	1vhxA
Description:	Crystal structure of Putative Holliday junction resolvase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nuclease activity	1.80465910244067	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.67622280196747	bayes_pls_golite062009
ribonuclease activity	0.567315548679559	bayes_pls_golite062009
exonuclease activity	0.550209133970558	bayes_pls_golite062009
hydrolase activity	0.482149639923564	bayes_pls_golite062009
endonuclease activity	0.164428265680495	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: