YRC Public Data Repository - Protein Structure Prediction

Protein:	GPDA_DESVH
Organism:	Desulfovibrio vulgaris str. Hildenborough
Length:	330 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPDA_DESVH.

Description	E-value	Query Range	Subject Range
GPDA_LEPIC - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Leptospira interrogans serogroup Icterohaemorrhagiae... GPDA_LEPIC - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Leptospira interrogans serogroup Icterohaemorrhagiae...	265.0	[0..1]	[330..1]
GPDA_LEPIN - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Leptospira interrogans serogroup Icterohaemorrhagiae... GPDA_LEPIN - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Leptospira interrogans GN=gpsA PE=3 SV=1	265.0	[0..1]	[330..1]
GPDA_LEPBJ - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Leptospira borgpetersenii serovar Hardjo-bovis (stra...	264.0	[0..1]	[330..1]
GPDA_LEPBL - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Leptospira borgpetersenii serovar Hardjo-bovis (stra...	263.0	[0..1]	[330..1]
gi\|238856808, gi... - gi\|238856808\|ref\|ZP_04647068.1\| glycerol-3-phosphate dehydrogenase [Enterococcus faecalis TUSoD Ef11... gi\|229305101, gi... - gi\|229549832\|ref\|ZP_04438557.1\| NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Enterococcus f... GPDA_ENTFA - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Enterococcus faecalis (strain ATCC 700802 / V583) GN... gi\|227073624, gi... - gi\|227518935\|ref\|ZP_03948984.1\| NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Enterococcus f... GPDA_ENTFA - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Enterococcus faecalis GN=gpsA PE=3 SV=1 gi\|229309209, gi... - gi\|229545641\|ref\|ZP_04434366.1\| NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Enterococcus f... gi\|227553554, gi... - gi\|227553554\|ref\|ZP_03983603.1\| NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Enterococcus f...	251.0	[0..2]	[330..4]
GPDA_OCEIH - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Oceanobacillus iheyensis GN=gpsA PE=3 SV=1 GPDA_OCEIH - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 113...	250.0	[0..2]	[330..3]
GPDA_GEOSL - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12... GPDA_GEOSL - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Geobacter sulfurreducens GN=gpsA PE=3 SV=1	250.0	[0..2]	[330..4]
GPDA_STRMU - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Streptococcus mutans serotype c (strain ATCC 700610 ... GPDA_STRMU - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Streptococcus mutans GN=gpsA PE=3 SV=1	248.0	[0..2]	[330..5]
GPDA_LACBA - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Lactobacillus brevis (strain ATCC 367 / JCM 1170) GN...	248.0	[0..2]	[330..4]
GPDA_DESVV - Glycerol-3-phosphate dehydrogenase [NAD(P)+] OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) ...	247.0	[0..1]	[330..1]

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Predicted Domain #1

Region A:
Residues: [1-330]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIAVLGGGS WGTALAHLLA GKGEDVRLWV RDPAVVEGVN RDHENPRYLK GLHLHEALRA  60
   61 TCDAGEALEG ADILLSVVPC QQTRTVLRSL RPRLKTGMVV VSASKGIETD GLRTVGEMVE 120
  121 DELAGLAPRY AVISGPSFAA EVVAGMPTAV VLGCADRDLG GTLREVFSTP TFRTYSCTDV 180
  181 RGVELGGAVK NVIAIAAGLS DGLGFGSNAR AGLITRGLAE MGRLGVALGA RGSTFMGLSG 240
  241 LGDLVLTCTG DLSRNRQVGL RLAEGQGLDA IVAGMGMVAE GVKTTEAVYE LAQREGVDLP 300
  301 ITQAMYAVLH DGRDPRDMVQ ELMTRELREE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.045757
Match:	1evyA
Description:	Glycerol-3-phosphate dehydrogenase; Glycerol-3- phosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycerol-3-phosphate dehydrogenase activity	5.69778822954678	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	2.94416173750168	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	2.26153457113968	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
coenzyme binding	1.75381990395214	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	1.38286873947786	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	1.2944666056092	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.21748262163777	bayes_pls_golite062009
retinol dehydrogenase activity	1.16811519855038	bayes_pls_golite062009
oxidoreductase activity	0.9367410227151	bayes_pls_golite062009
binding	0.784517759335365	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.602741520623622	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.526220107896909	bayes_pls_golite062009
DNA binding	0.525227236870065	bayes_pls_golite062009
nucleic acid binding	0.459537641913493	bayes_pls_golite062009
NAD or NADH binding	0.44922383360529	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
glycerol-3-phosphate dehydrogenase (NAD+) activity	0.288558688124398	bayes_pls_golite062009
transporter activity	0.270546223513707	bayes_pls_golite062009
L-iditol 2-dehydrogenase activity	0.198746846996811	bayes_pls_golite062009
transcription regulator activity	0.152651308844322	bayes_pls_golite062009
transmembrane transporter activity	0.0739813185157518	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: