YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|151944254
Organism:	Saccharomyces cerevisiae YJM789
Length:	633 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|151944254.

Description	E-value	Query Range	Subject Range
gi\|190409261 - gi\|190409261\|gb\|EDV12526.1\| GTPase activating protein for Ypt6 [Saccharomyces cerevisiae RM11-1a] MSB3 - GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its acti... gi\|151944254 - gi\|151944254\|gb\|EDN62533.1\| GTPase-activating protein [Saccharomyces cerevisiae YJM789] gi\|207341956 - gi\|207341956\|gb\|EDZ69870.1\| YNL293Wp-like protein [Saccharomyces cerevisiae AWRI1631] GYP3_YEAST - GTPase-activating protein GYP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSB3 PE=1...	0.0	[1..633]	[1..633]
TBCD1_BOVIN, TBC... - TBC1 domain family member 1 (Fragment) OS=Bos taurus GN=TBC1D1 PE=2 SV=1, (O97790) TBC1 domain famil...	6.0E-91	[36..628]	[5..537]
gi\|14041976 - gi\|14041976\|dbj\|BAB55057.1\| unnamed protein product [Homo sapiens]	1.0E-90	[24..628]	[113..655]
gi\|9790251, gi\|9... - gi\|988221\|gb\|AAA85223.1\| Tbc1, gi\|9790251\|ref\|NP_062610.1\| TBC1 domain family, member 1 [Mus musculu...	1.0E-83	[24..615]	[565..1094]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNDQQRFSL QNRTVLAHPY KRLGGAFTVK SPSVPNFHDK MHSDHSSSDS ALVNGSFRAN  60
   61 DHRSVEPSCL GQASPSEHDG NLSVIDLYGD EVESQRAEGE DDDDNNGDNG NEDLEEVHSD 120
  121 DLDLVPDDDN R

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [132-363]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRVELEGAAS ATSANSNGIN NTHFDRYGFK KQNNYISEAE YDKWWVEYSQ YCVRRKHKWQ  60
   61 LLLEKSGLPV TDDSPSRFPS KSERLKRYVR KGIPAEWRGN AWWHFARGQE KLNKNKGVYS 120
  121 QLLRKMKQIK KQNPNEKQVQ DLDIIERDLN RTFPDNIHFQ SSLHNKEGPP IIKSLRRVLV 180
  181 AFSLYNPKIG YCQSMNFLAG LLLLFLDEER AFWMLVIITS RYLPGVHNIN LE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [447-458]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIWDCLFYEE SH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.154902
Match:	1fkmA_
Description:	Ypt/Rab-GAP domain of gyp1p
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [364-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVNIDQGVLM LCVKEYIPEV WSYIKPSIDH HQKNNKTFSP SNKKVLFNMQ KNEFLYRLPP  60
   61 ITLCTASWFM SCFVGVVPIE TTL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.154902
Match:	1fkmA_
Description:	Ypt/Rab-GAP domain of gyp1p
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [459-525]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLFKVSLAVL KLSEHDLSKI KPRNNSLNYS WGSNLNQRGG SMGQEDSDME IFQVIQTFPK  60
   61 TLLNPNE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [526-633]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFEKIIFKRR FNLNRLDQDE IDRCRKFVAA QRLKFKTYGE LLGNSTSEAD LPINDNTDNK  60
   61 GIHITSDAVN EALSSEVYGF KKSLAGVHWN NSIKEKVKQM RKKKDKGD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits