YRC Public Data Repository - Protein Structure Prediction

Protein:	GARD_ECOLI
Organism:	Escherichia coli
Length:	523 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GARD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194438829, gi... - gi\|83585767\|ref\|ZP_00924408.1\| COG2721: Altronate dehydratase [Escherichia coli 101-1], gi\|194438829... gi\|242378672, gi... - gi\|251786399\|ref\|YP_003000703.1\| hypothetical protein B21_02944 [Escherichia coli BL21], gi\|24237867... gi\|253974971, gi... - gi\|254163070\|ref\|YP_003046178.1\| (D)-galactarate dehydrogenase [Escherichia coli B str. REL606], gi\|... gi\|254289820, gi... - gi\|254289820\|ref\|YP_003055568.1\| (D)-galactarate dehydrogenase [Escherichia coli BL21(DE3)], gi\|2539...	808.0	[0..1]	[523..1]
gi\|157068291, gi... - gi\|75197077\|ref\|ZP_00707147.1\| COG2721: Altronate dehydratase [Escherichia coli HS], gi\|157162611\|re...	808.0	[0..1]	[523..1]
gi\|188490327, gi... - gi\|75513338\|ref\|ZP_00735762.1\| COG2721: Altronate dehydratase [Escherichia coli 53638], gi\|188495128...	807.0	[0..1]	[523..1]
gi\|254795076, gi... - gi\|254795076\|ref\|YP_003079913.1\| (D)-galactarate dehydrogenase [Escherichia coli O157:H7 str. TW1435... gi\|208814132, gi... - gi\|208814132\|ref\|ZP_03255461.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4045], gi\|2... gi\|208740790, gi... - gi\|208820667\|ref\|ZP_03260987.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|209157343, gi... - gi\|209395943\|ref\|YP_002272599.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4115], gi\|... gi\|217327322, gi... - gi\|217327322\|ref\|ZP_03443405.1\| galactarate dehydratase [Escherichia coli O157:H7 str. TW14588], gi\|... gi\|189374159, gi... - gi\|189374159\|gb\|EDU92575.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC869], gi\|168786... gi\|168797726, gi... - gi\|189379748\|gb\|EDU98164.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC508], gi\|168797... gi\|195938347 - gi\|195938347\|ref\|ZP_03083729.1\| putative hydrolase [Escherichia coli O157:H7 str. EC4024] gi\|208805955, gi... - gi\|208805955\|ref\|ZP_03248292.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4206], gi\|2... gi\|189367620, gi... - gi\|189367620\|gb\|EDU86036.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4501], gi\|16876... gi\|189361494, gi... - gi\|189361494\|gb\|EDU79913.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4486], gi\|16876... gi\|168773207, gi... - gi\|187770841\|gb\|EDU34685.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|15833260, gi\|... - gi\|15833260\|ref\|NP_312033.1\| putative hydrolase [Escherichia coli O157:H7 str. Sakai], gi\|13363479\|d... gi\|189001138, gi... - gi\|189001138\|gb\|EDU70124.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4076], gi\|16878... gi\|168749278, gi... - gi\|188016380\|gb\|EDU54502.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4113], gi\|16874... gi\|189358663, gi... - gi\|189358663\|gb\|EDU77082.1\| galactarate dehydratase [Escherichia coli O157:H7 str. EC4401], gi\|16875... gi\|209758716, gi... - pir\|\|F91129 probable hydrolase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952... gi\|15833260, gi\|... - gi\|15833260\|ref\|NP_312033.1\| putative hydrolase [Escherichia coli O157:H7], gi\|13363479\|dbj\|BAB37429...	806.0	[0..1]	[523..1]
gi\|26249710, gi\|... - gi\|26249710\|ref\|NP_755750.1\| D-galactarate dehydratase [Escherichia coli CFT073], gi\|26110138\|gb\|AAN... gi\|227835248, gi... - gi\|227887852\|ref\|ZP_04005657.1\| D-galactarate dehydratase [Escherichia coli 83972], gi\|227835248\|gb\|...	806.0	[0..1]	[523..1]
gi\|218696833, gi... - gi\|218696833\|ref\|YP_002404500.1\| (D)-galactarate dehydrogenase [Escherichia coli 55989], gi\|21835356... gi\|218362466, gi... - gi\|218555698\|ref\|YP_002388611.1\| (D)-galactarate dehydrogenase [Escherichia coli IAI1], gi\|218362466... gi\|193062014, gi... - gi\|75260056\|ref\|ZP_00731334.1\| COG2721: Altronate dehydratase [Escherichia coli E22], gi\|193062014\|r... gi\|193067269, gi... - gi\|75239275\|ref\|ZP_00723246.1\| COG2721: Altronate dehydratase [Escherichia coli E110019], gi\|1930672... gi\|209913862, gi... - gi\|209920603\|ref\|YP_002294687.1\| galactarate dehydratase [Escherichia coli SE11], gi\|209913862\|dbj\|B... gi\|75211077, gi\|... - gi\|75211077\|ref\|ZP_00711190.1\| COG2721: Altronate dehydratase [Escherichia coli B171], gi\|194427765\|... gi\|75187934, gi\|... - gi\|75187934\|ref\|ZP_00701201.1\| COG2721: Altronate dehydratase [Escherichia coli E24377A], gi\|1571556...	806.0	[0..1]	[523..1]
gi\|25337009 - pir\|\|F85974 probable hydrolase yhaG [imported] - Escherichia coli (strain O157:H7, substrain EDL933... gi\|15803666, gi\|... - gi\|15803666\|ref\|NP_289699.1\| putative hydrolase [Escherichia coli O157:H7 EDL933], gi\|12517721\|gb\|AA...	806.0	[0..1]	[523..1]
gi\|115514552, gi... - gi\|117625428\|ref\|YP_858751.1\| putative D-galactarate dehydratase [Escherichia coli APEC O1], gi\|1155... gi\|218366973, gi... - gi\|218560204\|ref\|YP_002393117.1\| (D)-galactarate dehydrogenase [Escherichia coli S88], gi\|218366973\|... gi\|237706116, gi... - gi\|237706116\|ref\|ZP_04536597.1\| D-galactarate dehydratase [Escherichia sp. 3_2_53FAA], gi\|226899156\|... gi\|91212550, gi\|... - gi\|91212550\|ref\|YP_542536.1\| putative D-galactarate dehydratase [Escherichia coli UTI89], gi\|9107412...	806.0	[0..1]	[523..1]
gi\|218691422, gi... - gi\|218691422\|ref\|YP_002399634.1\| (D)-galactarate dehydrogenase [Escherichia coli ED1a], gi\|218428986... gi\|110643371, gi... - gi\|110643371\|ref\|YP_671101.1\| D-galactarate dehydratase [Escherichia coli 536], gi\|110344963\|gb\|ABG7... gi\|190907488, gi... - gi\|75240845\|ref\|ZP_00724743.1\| COG2721: Altronate dehydratase [Escherichia coli F11], gi\|191172178\|r...	805.0	[0..1]	[523..1]
gi\|73857152, gi\|... - gi\|74313675\|ref\|YP_312094.1\| putative hydrolase [Shigella sonnei Ss046], gi\|73857152\|gb\|AAZ89859.1\| ...	802.0	[0..1]	[523..1]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANIEIRQET PTAFYIKVHD TDNVAIIVND NGLKAGTRFP DGLELIEHIP QGHKVALLDI  60
   61 PANGEIIRYG EVIGYAVRAI PRGSWIDESM VVLPEAPPLH T

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	12.337242
Match:	PF08666.3
Description:	No description for PF08666.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.412	0.182	lyase activity	b.1.18	E set domains
View	Download	0.392	0.051	hydro-lyase activity	b.1.2	Fibronectin type III
View	Download	0.462	0.035	hydro-lyase activity	b.43.4	Riboflavin synthase domain-like
View	Download	0.351	0.002	hydro-lyase activity	d.82.2	Frataxin-like
View	Download	0.347	0.002	hydro-lyase activity	b.61.5	Dipeptidyl peptidase I (cathepsin C), exclusion domain

Predicted Domain #2

Region A:
Residues: [102-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLATKVPEP LPPLEGYTFE GYRNADGSVG TKNLLGITTS VHCVAGVVDY VVKIIERDLL  60
   61 PKYPNVDGVV GLNHLYGCGV AINAPAAVVP IRTIHNISLN PNFGGEVMVI GLGCEKLQPE 120
  121 RLLTGTDDVQ AIPVESASIV SLQDEKHVGF QSMVEDILQI AERHLQKLNQ RQRETCPASE 180
  181 LVVGMQCGGS DAFSGVTANP AVGYASDLLV RCGATVMFSE VTEVRDAIHL LTPRAVNEEV 240
  241 G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [343-523]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRLLEEMEWY DNYLNMGKTD RSANPSPGNK KGGLANVVEK ALGSIAKSGK SAIVEVLSPG  60
   61 QRPTKRGLIY AATPASDFVC GTQQVASGIT VQVFTTGRGT PYGLMAVPVI KMATRTELAN 120
  121 RWFDLMDINA GTIATGEETI EEVGWKLFHF ILDVASGKKK TFSDQWGLHN QLAVFNPAPV 180
  181 T

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits