YRC Public Data Repository - Protein Structure Prediction

Protein:	FSR_ECOLI
Organism:	Escherichia coli
Length:	406 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FSR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	189.0	[0..12]	[404..289]
gi\|218202668 - gi\|218202668\|gb\|EEC85095.1\| hypothetical protein OsI_32467 [Oryza sativa Indica Group] PHT44_ORYSJ - Probable anion transporter 4, chloroplastic OS=Oryza sativa subsp. japonica GN=PHT4;4 PE=2 SV=1	184.0	[0..21]	[405..179]
gi\|92892758 - gi\|92892758\|gb\|ABE91392.1\| Major facilitator superfamily MFS_1 [Medicago truncatula]	180.0	[0..21]	[405..176]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	178.0	[0..4]	[405..430]
gi\|68389434 - gi\|68389434\|ref\|XP_691920.1\| PREDICTED: similar to solute carrier family 17 (sodium-dependent inorga...	177.0	[0..21]	[406..141]
gi\|17064976, gi\|... - gi\|21387197\|gb\|AAM48002.1\| putative Na+-dependent inorganic phosphate cotransporter [Arabidopsis tha...	171.0	[0..21]	[405..100]
VGLU2_BOVIN - Vesicular glutamate transporter 2 OS=Bos taurus GN=SLC17A6 PE=2 SV=1	165.0	[0..21]	[406..68]
VGLU2_MOUSE - Vesicular glutamate transporter 2 OS=Mus musculus GN=Slc17a6 PE=1 SV=1	163.0	[0..21]	[406..68]

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Predicted Domain #1

Region A:
Residues: [1-406]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMSEQPQPV AGAAASTTKA RTSFGILGAI SLSHLLNDMI QSLILAIYPL LQSEFSLTFM  60
   61 QIGMITLTFQ LASSLLQPVV GYWTDKYPMP WSLPIGMCFT LSGLVLLALA GSFGAVLLAA 120
  121 ALVGTGSSVF HPESSRVARM ASGGRHGLAQ SIFQVGGNFG SSLGPLLAAV IIAPYGKGNV 180
  181 AWFVLAALLA IVVLAQISRW YSAQHRMNKG KPKATIINPL PRNKVVLAVS ILLILIFSKY 240
  241 FYMASISSYY TFYLMQKFGL SIQNAQLHLF AFLFAVAAGT VIGGPVGDKI GRKYVIWGSI 300
  301 LGVAPFTLIL PYASLHWTGV LTVIIGFILA SAFSAILVYA QELLPGRIGM VSGLFFGFAF 360
  361 GMGGLGAAVL GLIADHTSIE LVYKICAFLP LLGMLTIFLP DNRHKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	2.54286095434601	bayes_pls_golite062009
transmembrane transporter activity	2.01247278444729	bayes_pls_golite062009
substrate-specific transporter activity	1.77039368764865	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.66673693200184	bayes_pls_golite062009
active transmembrane transporter activity	0.33203350453105	bayes_pls_golite062009
polyol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.2309068592963	bayes_pls_golite062009
ion transmembrane transporter activity	0.18188709249385	bayes_pls_golite062009
binding	0.105551689569449	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	1.26964387230144E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: