YRC Public Data Repository - Protein Structure Prediction

Protein:	FLHC_ECOLI
Organism:	Escherichia coli
Length:	192 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FLHC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|49611146, gi\|... - gi\|50120620\|ref\|YP_049787.1\| transcriptional activator FlhC [Pectobacterium atrosepticum SCRI1043], ...	327.0	[0..1]	[192..1]
gi\|194439059, gi... - gi\|83585509\|ref\|ZP_00924153.1\| hypothetical protein Ecol1_01003239 [Escherichia coli 101-1], gi\|1944...	320.0	[0..1]	[192..1]
gi\|75239690, gi\|... - gi\|75239690\|ref\|ZP_00723653.1\| hypothetical protein EcolF_01002887 [Escherichia coli F11], gi\|191172... gi\|110642007, gi... - gi\|110642007\|ref\|YP_669737.1\| transcriptional activator FlhC [Escherichia coli 536], gi\|110343599\|gb...	319.0	[0..1]	[192..1]
FLHC_SERMA - Flagellar transcriptional regulator FlhC OS=Serratia marcescens GN=flhC PE=3 SV=1	318.0	[0..1]	[192..2]
gi\|122089767, gi... - gi\|123442806\|ref\|YP_001006783.1\| transcriptional activator FlhC [Yersinia enterocolitica subsp. ente... FLHC_YEREN - Flagellar transcriptional regulator FlhC OS=Yersinia enterocolitica GN=flhC PE=3 SV=1 gi\|238785462, gi... - gi\|77957114\|ref\|ZP_00821179.1\| hypothetical protein YberA_01002669 [Yersinia bercovieri ATCC 43970],...	318.0	[0..1]	[192..1]
gi\|77960503, gi\|... - gi\|77960503\|ref\|ZP_00824371.1\| hypothetical protein YmolA_01003217 [Yersinia mollaretii ATCC 43969],...	318.0	[0..1]	[192..1]
gi\|67009941 - gi\|67009941\|dbj\|BAD99453.1\| transcriptional activator [Shigella boydii]	318.0	[0..1]	[192..1]
gi\|145318991, gi... - gi\|146312115\|ref\|YP_001177189.1\| transcriptional activator FlhC [Enterobacter sp. 638], gi\|145318991... gi\|15551740 - gi\|15551740\|emb\|CAC69398.1\| flhC protein [Enterobacter sp. 22]	318.0	[0..1]	[192..1]
gi\|145984 - gi\|145984\|gb\|AAA23788.1\| FlaI protein	317.0	[0..1]	[192..1]
FLHC_XENNE - Flagellar transcriptional regulator FlhC OS=Xenorhabdus nematophila GN=flhC PE=3 SV=1	317.0	[0..1]	[192..1]

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Predicted Domain #1

Region A:
Residues: [1-192]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKSIVQEA RDIQLAMELI TLGARLQMLE SETQLSRGRL IKLYKELRGS PPPKGMLPFS  60
   61 TDWFMTWEQN VHASMFCNAW QFLLKTGLCN GVDAVIKAYR LYLEQCPQAE EGPLLALTRA 120
  121 WTLVRFVESG LLQLSSCNCC GGNFITHAHQ PVGSFACSLC QPPSRAVKRR KLSQNPADII 180
  181 PQLLDEQRVQ AV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.522879
Match:	2avuE
Description:	Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.76728328288819	bayes_pls_golite062009
transcription activator activity	0.41227092363175	bayes_pls_golite062009
transcription repressor activity	0.334304405404029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: