YRC Public Data Repository - Protein Structure Prediction

Protein:	FEAR_ECOLI
Organism:	Escherichia coli
Length:	301 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FEAR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|157066546, gi... - gi\|75195501\|ref\|ZP_00705571.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	183.0	[0..1]	[301..1]
gi\|209918660, gi... - gi\|209918660\|ref\|YP_002292744.1\| DNA-binding transcriptional activator FeaR [Escherichia coli SE11],... gi\|188496301, gi... - gi\|75515026\|ref\|ZP_00737230.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|157081340, gi... - gi\|75190441\|ref\|ZP_00703708.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|83571033, gi\|... - gi\|83571033\|ref\|ZP_00922475.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Shigella d...	183.0	[0..1]	[301..1]
gi\|75259509 - gi\|75259509\|ref\|ZP_00730828.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|75212796 - gi\|75212796\|ref\|ZP_00712794.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	182.0	[0..1]	[301..1]
gi\|75231848, gi\|... - gi\|75231848\|ref\|ZP_00718189.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	177.0	[0..6]	[301..2]
gi\|111025840, gi... - gi\|111025840\|ref\|YP_708260.1\| AraC family transcriptional regulator [Rhodococcus jostii RHA1], gi\|11...	167.0	[0..5]	[299..20]
gi\|54024064, gi\|... - gi\|54024064\|ref\|YP_118306.1\| putative transcriptional regulator [Nocardia farcinica IFM 10152], gi\|5...	159.0	[0..2]	[297..9]
gi\|221235418, gi... - gi\|221235418\|ref\|YP_002517855.1\| transcriptional regulator, AraC family [Caulobacter crescentus NA10... gi\|25399791 - pir\|\|F87546 transcription regulator, AraC family [imported] - Caulobacter crescentus gi\|13423936, gi\|... - gi\|16126638\|ref\|NP_421202.1\| AraC family transcriptional regulator [Caulobacter crescentus CB15], gi...	158.0	[0..9]	[298..17]
gi\|167843684 - gi\|167843684\|ref\|ZP_02469192.1\| putative transcriptional regulator [Burkholderia pseudomallei B7210] gi\|126227941, gi... - gi\|82532538\|ref\|ZP_00891749.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Burkholder... gi\|167908890 - gi\|167908890\|ref\|ZP_02495981.1\| putative transcriptional regulator [Burkholderia pseudomallei 112] gi\|242138398, gi... - gi\|90662049\|ref\|ZP_01249885.1\| hypothetical protein Bpse110_02006026 [Burkholderia pseudomallei 1106... gi\|67752657, gi\|... - gi\|67752657\|ref\|ZP_00491625.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Burkholder...	158.0	[0..5]	[299..14]
gi\|167736458 - gi\|167736458\|ref\|ZP_02409232.1\| AraC family regulatory protein [Burkholderia pseudomallei 14] gi\|53717684, gi\|... - gi\|53717684\|ref\|YP_106670.1\| AraC family transcription regulator [Burkholderia pseudomallei K96243],... gi\|254298620, gi... - gi\|83676787\|ref\|ZP_00938557.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Burkholder... gi\|161371789, gi... - gi\|90291141\|ref\|ZP_01210775.1\| hypothetical protein Bpse17_02004211 [Burkholderia pseudomallei 1710a... gi\|76811943, gi\|... - gi\|76811943\|ref\|YP_331679.1\| AraC family transcription regulator [Burkholderia pseudomallei 1710b], ... gi\|134247040, gi... - gi\|134281373\|ref\|ZP_01768081.1\| transcriptional regulator, AraC family [Burkholderia pseudomallei 30... gi\|237814442, gi... - gi\|237814442\|ref\|YP_002898893.1\| AraC family regulatory protein [Burkholderia pseudomallei MSHR346],...	158.0	[0..5]	[299..14]

Back

Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPAVDNEFQ QWLSQINQVC GNFTGRLLTE RYTGVLDTHF AKGLKLSTVT TSGVNLSRTW  60
   61 QEVKGSDDAW FYTVFQLSGQ AIMEQDERQV QIGAGDITLL DASRPCSLYW QESSKQISLL 120
  121 LPRTLLEQY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.522879
Match:	1vj2A
Description:	Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.77242843392921	bayes_pls_golite062009
binding	0.729506188425605	bayes_pls_golite062009
transcription regulator activity	0.707930119310256	bayes_pls_golite062009
nucleic acid binding	0.0202006356795219	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [130-301]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPHQKPICAE RLDADLPMVQ LSHRLLQESM NNPALSETES EAALQAMVCL LRPVLHQRES  60
   61 VQPRRERQFQ KVVTLIDDNI REEILRPEWI AGETGMSVRS LYRMFADKGL VVAQYIRNRR 120
  121 LDFCADAIRH AADDEKLAGI GFHWGFSDQS HFSTVFKQRF GMTPGEYRRK FR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.39794
Match:	1wpkA
Description:	Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: