YRC Public Data Repository - Protein Structure Prediction

Protein:	FABZ_YERPE
Organism:	Yersinia pestis
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABZ_YERPE.

Description	E-value	Query Range	Subject Range
FABZ_YEREN - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia enterocolitica GN=fabZ PE=3 SV=2	2.0E-59	[1..181]	[1..178]
FABZ_YERPY - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype O:3 (s... gi\|167470462 - gi\|167470462\|ref\|ZP_02335166.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... FABZ_YERPB - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype IB (st... FABZ_YERPS - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype I (str... FABZ_YERP3 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype O:1b (... FABZ_YERPG - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis bv. Antiqua (strain Angola)... gi\|166207125, gi... - gi\|166211354\|ref\|ZP_02237389.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|166011911, gi... - gi\|166011911\|ref\|ZP_02232809.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|229704139, gi... - gi\|229837762\|ref\|ZP_04457922.1\| (3R)-hydroxymyristol acyl carrier protein dehydratase [Yersinia pest... gi\|167055736, gi... - gi\|167425336\|ref\|ZP_02317089.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|167399930, gi... - gi\|167399930\|ref\|ZP_02305448.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... FABZ_YERPA - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis bv. Antiqua (strain Antiqua... FABZ_YERPP - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis (strain Pestoides F) GN=fab... FABZ_YERPN - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis bv. Antiqua (strain Nepal51... gi\|45437428, gi\|... - gi\|45442563\|ref\|NP_994102.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Yersinia pestis biovar Microtus ... gi\|21960046, gi\|... - gi\|22127000\|ref\|NP_670423.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Yersinia pestis KIM], gi\|2196004... FABZ_YERPS - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Yersinia pseudotuberculosis GN=fabZ PE=3...	6.0E-54	[1..181]	[1..176]
gi\|238792744, gi... - gi\|77977737\|ref\|ZP_00833178.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ...	1.0E-53	[1..168]	[24..192]
gi\|77972721 - gi\|77972721\|ref\|ZP_00828280.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ...	4.0E-53	[1..181]	[1..167]
gi\|90413540, gi\|... - gi\|90413540\|ref\|ZP_01221531.1\| (3R)-hydroxymyristoyl ACP dehydratase [Photobacterium profundum 3TCK]...	8.0E-52	[1..149]	[1..149]
FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum GN=fabZ PE=3 SV=1 FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum (strain SS9) GN=fa...	8.0E-52	[1..149]	[1..149]
gi\|24050384, gi\|... - ref\|NP_706125.1\| (3R)-hydroxymyristol acyl carrier protein dehydratase [Shigella flexneri 2a str. 30... gi\|26106523, gi\|... - gi\|26246126\|ref\|NP_752165.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Escherichia coli CFT073], gi\|261... gi\|110804232, gi... - gi\|110804232\|ref\|YP_687752.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Shigella flexneri 5 str. 8401],... gi\|91070824, gi\|... - gi\|91209250\|ref\|YP_539236.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Escherichia coli UTI89], gi\|9107...	9.0E-52	[1..151]	[32..182]
gi\|238784891, gi... - gi\|77957700\|ref\|ZP_00821749.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ... gi\|77963164 - gi\|77963164\|ref\|ZP_00826976.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ...	2.0E-51	[1..165]	[24..184]
lcl\|NC_016856.1_... - [gene=fabZ] [protein=(3R)-hydroxymyristoyl-ACP dehydratase] [protein_id=YP_005235899.1] [location=26... gi\|62126430, gi\|... - gi\|62178797\|ref\|YP_215214.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. enter...	2.0E-51	[1..151]	[31..181]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDTHTLHI EEILDLLPHR FPFLLVDRVL DFEEGKFLRA VKNVSFNEPF FQGHFPGKPI  60
   61 FPGVLILEAM AQATGILAFK SRGKLEPGEL YYFAGIDEAR FKRPVVPGDQ MIMEVEFVKE 120
  121 RRGLTRFTGV AKVDGEIVCT ATMMCARSKP AAPAESVVVK PDVVKPDVVK PDVVNPVVKE 180
  181 S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.39794
Match:	1u1zA
Description:	The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
CoA hydrolase activity	1.75530090056705	bayes_pls_golite062009
catalytic activity	1.11649534052993	bayes_pls_golite062009
thiolester hydrolase activity	0.65794221902015	bayes_pls_golite062009
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.24094527143225	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: