YRC Public Data Repository - Protein Structure Prediction

Protein:	EFTS_SALTY
Organism:	Salmonella typhimurium
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EFTS_SALTY.

Description	E-value	Query Range	Subject Range
gi\|62178787, gi\|... - gi\|62178787\|ref\|YP_215204.1\| elongation factor Ts [Salmonella enterica subsp. enterica serovar Chole... gi\|161361952, gi... - gi\|161612588\|ref\|YP_001586553.1\| elongation factor Ts [Salmonella enterica subsp. enterica serovar P...	0.0	[1..283]	[25..307]
sp\|B7UIL5\|EFTS_ECO27 - Elongation factor Ts OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=tsf PE=3 SV=1 EFTS_SHISS - Elongation factor Ts OS=Shigella sonnei (strain Ss046) GN=tsf PE=3 SV=1 EFTS_ECOL6 - Elongation factor Ts OS=Escherichia coli O6 GN=tsf PE=3 SV=2 gi\|192931096, gi... - gi\|75258841\|ref\|ZP_00730231.1\| COG0264: Translation elongation factor Ts [Escherichia coli E22], gi\|... gi\|75512182, gi\|... - gi\|75512182\|ref\|ZP_00734754.1\| COG0264: Translation elongation factor Ts [Escherichia coli 53638], g... EFTS_SHIDS - Elongation factor Ts OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=tsf PE=3 SV=1 EFTS_SHIBS - Elongation factor Ts OS=Shigella boydii serotype 4 (strain Sb227) GN=tsf PE=3 SV=1 EFTS_ECO24 - Elongation factor Ts OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=tsf PE=3 SV=1 gi\|227838055, gi... - gi\|227884917\|ref\|ZP_04002722.1\| elongation factor Ts protein [Escherichia coli 83972], gi\|227838055\|... EFTS_ECOHS - Elongation factor Ts OS=Escherichia coli O9:H4 (strain HS) GN=tsf PE=3 SV=1 gi\|226902241, gi... - gi\|237704329\|ref\|ZP_04534810.1\| elongation factor Ts [Escherichia sp. 3_2_53FAA], gi\|226902241\|gb\|EE... gi\|83585486, gi\|... - gi\|83585486\|ref\|ZP_00924131.1\| COG0264: Translation elongation factor Ts [Escherichia coli 101-1], g... EFTS_ECOBW - Elongation factor Ts OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=tsf PE=3 SV=1 EFTS_SHIB3 - Elongation factor Ts OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=tsf PE=3 SV=1 gi\|242376002, gi... - gi\|251783729\|ref\|YP_002998033.1\| hypothetical protein B21_00167 [Escherichia coli BL21], gi\|24237600... gi\|75238873, gi\|... - gi\|75238873\|ref\|ZP_00722855.1\| COG0264: Translation elongation factor Ts [Escherichia coli E110019],... gi\|253774803, gi... - gi\|254287092\|ref\|YP_003052840.1\| elongation factor Ts [Escherichia coli BL21(DE3)], gi\|253976399\|gb\|... gi\|75240241, gi\|... - gi\|75240241\|ref\|ZP_00724188.1\| COG0264: Translation elongation factor Ts [Escherichia coli F11], gi\|... gi\|254037589, gi... - gi\|254037589\|ref\|ZP_04871666.1\| translation elongation factor Ts [Escherichia sp. 1_1_43], gi\|226840... gi\|194413686, gi... - gi\|75210493\|ref\|ZP_00710644.1\| COG0264: Translation elongation factor Ts [Escherichia coli B171], gi... gi\|254160289, gi... - gi\|254160289\|ref\|YP_003043397.1\| elongation factor Ts [Escherichia coli B str. REL606], gi\|253972190... gi\|75230469, gi\|... - gi\|75230469\|ref\|ZP_00716950.1\| COG0264: Translation elongation factor Ts [Escherichia coli B7A], gi\|... gi\|254791303, gi... - gi\|254791303\|ref\|YP_003076140.1\| protein chain elongation factor EF-Ts [Escherichia coli O157:H7 str... EFTS_ECOLC - Elongation factor Ts OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=tsf PE=3 SV=1 EFTS_SHIFL - Elongation factor Ts OS=Shigella flexneri GN=tsf PE=3 SV=2 EFTS_ECOLI - Elongation factor Ts (EF-Ts) - Escherichia coli gi\|24050373, gi\|... - gi\|24111605\|ref\|NP_706115.1\| elongation factor Ts [Shigella flexneri 2a str. 301], gi\|24050373\|gb\|AA... EFTS_ECOL6 - Elongation factor Ts OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=tsf PE=3 SV=2 gi\|124499762, gi... - gi\|124529606\|ref\|ZP_01700550.1\| translation elongation factor Ts [Escherichia coli B], gi\|124499762\|... gi\|168764323, gi... - gi\|189365641\|gb\|EDU84057.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC4501],... gi\|189357099, gi... - gi\|189357099\|gb\|EDU75518.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC4401],... gi\|189000420, gi... - gi\|189000420\|gb\|EDU69406.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC4076],... gi\|168777007, gi... - gi\|187767672\|gb\|EDU31516.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC4196],... gi\|189375679, gi... - gi\|189375679\|gb\|EDU94095.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC508], ... gi\|189371103, gi... - gi\|189371103\|gb\|EDU89519.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC869], ... EFTS_ECOSM - Elongation factor Ts OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=tsf PE=3 SV=1 EFTS_ECODH - Elongation factor Ts OS=Escherichia coli (strain K12 / DH10B) GN=tsf PE=3 SV=1 gi\|15829426, gi\|... - gi\|15829426\|ref\|NP_308199.1\| elongation factor Ts [Escherichia coli O157:H7 str. Sakai], gi\|13359628... EFTS_ECOL5 - Elongation factor Ts OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=tsf PE=3 SV=1 EFTS_SHIF8 - Elongation factor Ts OS=Shigella flexneri serotype 5b (strain 8401) GN=tsf PE=3 SV=1 gi\|21239025, gi\|... - gi\|89107050\|ref\|AP_000830.1\| protein chain elongation factor EF-Ts [Escherichia coli str. K-12 subst... gi\|168751389, gi... - gi\|188014566\|gb\|EDU52688.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC4113],... EFTS_ECOUT - Elongation factor Ts OS=Escherichia coli (strain UTI89 / UPEC) GN=tsf PE=3 SV=1 gi\|30061727, gi\|... - gi\|30061727\|ref\|NP_835898.1\| elongation factor Ts [Shigella flexneri 2a str. 2457T], gi\|30039969\|gb\|... EFTS_ECO8A - Elongation factor Ts OS=Escherichia coli O8 (strain IAI1) GN=tsf PE=3 SV=1 EFTS_ECO57 - Elongation factor Ts OS=Escherichia coli O157:H7 GN=tsf PE=3 SV=2 EFTS_ESCF3 - Elongation factor Ts OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=tsf ... EG11033 - translation elongation factor EF-Ts / Translation elongation factor EF-Ts; exchanges GDP for GTP in ... EFTS_ECO81 - Elongation factor Ts OS=Escherichia coli O81 (strain ED1a) GN=tsf PE=3 SV=1 gi\|15799852, gi\|... - gi\|15799852\|ref\|NP_285864.1\| elongation factor Ts [Escherichia coli O157:H7 EDL933], gi\|12512895\|gb\|... EFTS_ECO45 - Elongation factor Ts OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=tsf PE=3 SV=1 EFTS_ECO7I - Elongation factor Ts OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=tsf PE=3 SV=1 EFTS_ECO55 - Elongation factor Ts OS=Escherichia coli (strain 55989 / EAEC) GN=tsf PE=3 SV=1 EFTS_ECOLU - Elongation factor Ts OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=tsf PE=3 SV=1 gi\|208729337, gi... - gi\|208809536\|ref\|ZP_03251873.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC42... gi\|195938148 - gi\|195938148\|ref\|ZP_03083530.1\| elongation factor Ts [Escherichia coli O157:H7 str. EC4024] EG11033 - translation elongation factor EF-Ts / Translation elongation factor EF-Ts; exchanges GDP for GTP in ... gi\|208822005, gi... - gi\|208822005\|ref\|ZP_03262325.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC40... gi\|208735591, gi... - gi\|208814314\|ref\|ZP_03255643.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. EC40... EFTS_ECOSE - Elongation factor Ts OS=Escherichia coli (strain SE11) GN=tsf PE=3 SV=1 EFTS_ECO5E - Elongation factor Ts OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=tsf PE=3 SV=1 gi\|217321304, gi... - gi\|217325083\|ref\|ZP_03441167.1\| translation elongation factor Ts [Escherichia coli O157:H7 str. TW14... EFTS_ECO27 - Elongation factor Ts OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=tsf PE=3 SV=1	0.0	[1..283]	[1..283]
gi\|194433429, gi... - gi\|83569752\|ref\|ZP_00921202.1\| COG0264: Translation elongation factor Ts [Shigella dysenteriae 1012]...	0.0	[1..283]	[1..283]
EFTS_PHOLL - Elongation factor Ts OS=Photorhabdus luminescens subsp. laumondii GN=tsf PE=3 SV=1 EFTS_PHOLL - Elongation factor Ts OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / T...	0.0	[1..281]	[1..283]
EFTS_SHIFL - (P0A6P4) Elongation factor Ts (EF-Ts) EFTS_ECOLI - (P0A6P1) Elongation factor Ts (EF-Ts) EFTS_ECO57 - (P0A6P3) Elongation factor Ts (EF-Ts) EFTS_ECOL6 - (P0A6P2) Elongation factor Ts (EF-Ts)	0.0	[2..283]	[1..282]
EFTS_SALPA - Elongation factor Ts OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=tsf PE=3 SV=1 EFTS_SALPA - Elongation factor Ts OS=Salmonella paratyphi A GN=tsf PE=3 SV=1 EFTS_SALPK - Elongation factor Ts OS=Salmonella paratyphi A (strain AKU_12601) GN=tsf PE=3 SV=1	0.0	[1..283]	[1..283]
EFTS_SODGM - Elongation factor Ts OS=Sodalis glossinidius (strain morsitans) GN=tsf PE=3 SV=1	0.0	[1..282]	[1..284]
gi\|229704129, gi... - gi\|229837752\|ref\|ZP_04457912.1\| protein chain elongation factor EF-Ts [Yersinia pestis Pestoides A],... gi\|229840974, gi... - gi\|229840974\|ref\|ZP_04461133.1\| protein chain elongation factor EF-Ts [Yersinia pestis biovar Orient... gi\|229689951, gi... - gi\|229843075\|ref\|ZP_04463225.1\| protein chain elongation factor EF-Ts [Yersinia pestis biovar Orient... gi\|149290568, gi... - gi\|149366954\|ref\|ZP_01888987.1\| elongation factor Ts [Yersinia pestis CA88-4125], gi\|149290568\|gb\|ED... EFTS_YERPG - Elongation factor Ts OS=Yersinia pestis bv. Antiqua (strain Angola) GN=tsf PE=3 SV=1 EFTS_YERPP - Elongation factor Ts OS=Yersinia pestis (strain Pestoides F) GN=tsf PE=3 SV=1 EFTS_YERP3 - Elongation factor Ts OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=tsf PE=3 SV=1 EFTS_YERPS - Elongation factor Ts OS=Yersinia pseudotuberculosis GN=tsf PE=3 SV=1 gi\|166962491, gi... - gi\|167419750\|ref\|ZP_02311503.1\| translation elongation factor Ts [Yersinia pestis biovar Orientalis ... gi\|167050757, gi... - gi\|167400049\|ref\|ZP_02305567.1\| translation elongation factor Ts [Yersinia pestis biovar Antiqua str... EFTS_YERPY - Elongation factor Ts OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=tsf PE=3 SV=1 gi\|167425292, gi... - gi\|167425292\|ref\|ZP_02317045.1\| translation elongation factor Ts [Yersinia pestis biovar Mediaevalis... EFTS_YERPB - Elongation factor Ts OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=tsf PE=3 SV=1 gi\|45437439, gi\|... - gi\|45442574\|ref\|NP_994113.1\| elongation factor Ts [Yersinia pestis biovar Microtus str. 91001], gi\|4... gi\|21960059, gi\|... - gi\|22127012\|ref\|NP_670435.1\| elongation factor Ts [Yersinia pestis KIM], gi\|21960059\|gb\|AAM86686.1\|A... gi\|115346824, gi... - gi\|218928213\|ref\|YP_002346088.1\| elongation factor Ts [Yersinia pestis CO92], gi\|16121345\|ref\|NP_404... gi\|165927067, gi... - gi\|165927067\|ref\|ZP_02222899.1\| translation elongation factor Ts [Yersinia pestis biovar Orientalis ... EFTS_YERPS - Elongation factor Ts OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=tsf PE=3 SV=1 gi\|89105135, gi\|... - gi\|89105135\|ref\|ZP_01177660.1\| COG0264: Translation elongation factor Ts [Yersinia pestis biovar Ori... EFTS_YERPA - Elongation factor Ts OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=tsf PE=3 SV=1 gi\|166211780, gi... - gi\|166211780\|ref\|ZP_02237815.1\| translation elongation factor Ts [Yersinia pestis biovar Antiqua str... EFTS_YERPE - Elongation factor Ts OS=Yersinia pestis GN=tsf PE=3 SV=1 EFTS_YERPN - Elongation factor Ts OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=tsf PE=3 SV=1 gi\|166011932, gi... - gi\|166011932\|ref\|ZP_02232830.1\| translation elongation factor Ts [Yersinia pestis biovar Antiqua str...	0.0	[1..283]	[1..285]
gi\|238727862, gi... - gi\|77977747\|ref\|ZP_00833188.1\| COG0264: Translation elongation factor Ts [Yersinia intermedia ATCC 2...	1.0E-99	[1..283]	[1..285]
EFTS_HISS2 - Elongation factor Ts OS=Histophilus somni (strain 2336) GN=tsf PE=3 SV=1 EFTS_HAES1 - Elongation factor Ts OS=Haemophilus somnus (strain 129Pt) GN=tsf PE=3 SV=1	2.0E-99	[1..281]	[1..280]

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Predicted Domain #1

Region A:
Residues: [1-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEITASLVK ELRERTGAGM MDCKKALTEA NGDIELAIEN MRKSGAIKAA KKAGNVAADG  60
   61 VIKTKIDGNV AFILEVNCQT DFVAKDAGFQ AFADKVLDAA VAGKITDVEV LKAQFEEERV 120
  121 ALVAKIGENI NIRRVASLEG DVLGSYQHGA RIGVLVAAKG ADEELVKQLA MHVAASKPEF 180
  181 VKPEDVSADV VEKEYQVQLD IAMQSGKPKE IAEKMVEGRM KKFTGEVSLT GQPFVMEPSK 240
  241 SVGQLLKEHN ADVTGFIRFE VGEGIEKVET DFAAEVAAMS KQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1efuB
Description:	Elongation factor Ts (EF-Ts), N-terminal domain; Elongation factor Ts (EF-Ts), dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation elongation factor activity	7.45583793023677	bayes_pls_golite062009
translation regulator activity	3.96278094372195	bayes_pls_golite062009
translation factor activity, nucleic acid binding	3.9473033844258	bayes_pls_golite062009
nucleic acid binding	3.24631360795453	bayes_pls_golite062009
binding	2.99802367172802	bayes_pls_golite062009
ubiquitin binding	0.83381750627184	bayes_pls_golite062009
small conjugating protein binding	0.643709242447801	bayes_pls_golite062009
transcription regulator activity	0.43285087811192	bayes_pls_golite062009
DNA binding	0.262676519883369	bayes_pls_golite062009
protein binding	0.259532204752794	bayes_pls_golite062009
catalytic activity	0.25774924710417	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: