YRC Public Data Repository - Protein Structure Prediction

Protein:	DHFRP1, DHFR
Organism:	Homo sapiens
Length:	186 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHFRP1, DHFR.

Description	E-value	Query Range	Subject Range
DYR_RAT - Dihydrofolate reductase OS=Rattus norvegicus GN=Dhfr PE=2 SV=3	216.0	[0..2]	[186..3]
DYR_MOUSE - Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=3	216.0	[0..2]	[186..3]
DYR_PIG - Dihydrofolate reductase OS=Sus scrofa GN=DHFR PE=1 SV=1 gi\|66093 - pir\|\|RDPGD dihydrofolate reductase (EC 1.5.1.3) - pig	215.0	[0..2]	[186..2]
gi\|85658490, gi\|... - gi\|88601320\|tpd\|FAA00073.1\| TPA: dihydrofolate reductase [Cricetulus griseus], gi\|85658490\|dbj\|BAE78... gi\|304502 - gi\|304502\|gb\|AAA36970.1\| dihydrofolate reductase (EC 1.5.1.3)	215.0	[0..2]	[185..3]
gi\|73984093 - gi\|73984093\|ref\|XP_851329.1\| PREDICTED: similar to Dihydrofolate reductase [Canis familiaris]	214.0	[0..3]	[186..8]
gi\|37654603 - gi\|37654603\|gb\|AAQ96635.1\| ubiquitin-ts degron; DHFR [Degron tagging vector pSMRG2+] gi\|37654599 - gi\|37654599\|gb\|AAQ96632.1\| ubiquitin-ts degron; DHFR [Degron tagging vector pSMUG2+]	214.0	[0..2]	[186..85]
DYR_MESAU - Dihydrofolate reductase OS=Mesocricetus auratus GN=DHFR PE=2 SV=4 gi\|191046 - gi\|191046\|gb\|AAA36971.1\| dihydrofolate reductase	213.0	[0..2]	[185..3]

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Predicted Domain #1

Region A:
Residues: [1-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGSLNCIVAV SQNMGIGKNG DLPWPPLRNE FRYFQRMTTT SSVEGKQNLV IMGKKTWFSI  60
   61 PEKNRPLKGR INLVLSRELK EPPQGAHFLS RSLDDALKLT EQPELANKVD MVWIVGGSSV 120
  121 YKEAMNHPGH LKLFVTRIMQ DFESDTFFPE IDLEKYKLLP EYPGVLSDVQ EEKGIKYKFE 180
  181 VYEKND

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.522879
Match:	2fzjA
Description:	No description for 2fzjA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits