| Protein: | dlg1-PB |
| Organism: | Drosophila melanogaster |
| Length: | 970 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dlg1-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
626.0 | [0..1] | [970..1] |
|
Region A: Residues: [1-90] |
1 11 21 31 41 51
| | | | | |
1 MPVKKQEAHR ALELLEDYHA RLSEPQDRAL RIAIERVIRI FKSRLFQALL DIQEFYELTL 60
61 LDDSKSIQQK TAETLQIATK WEKDGQAVKI
|
| Detection Method: |  |
| Confidence: | 9.0 |
| Match: | 1rsoA |
| Description: | Hetero-tetrameric L27 (Lin-2, Lin-7) domain complexes as organization platforms of supra-molecular assemblies |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleotide kinase activity | 3.97500450800152 | bayes_pls_golite062009 |
| phosphotransferase activity, phosphate group as acceptor | 3.5069571551747 | bayes_pls_golite062009 |
| nucleobase, nucleoside, nucleotide kinase activity | 3.18270433521719 | bayes_pls_golite062009 |
| binding | 2.4093171025758 | bayes_pls_golite062009 |
| protein binding | 2.20603141255185 | bayes_pls_golite062009 |
| PDZ domain binding | 1.88298566187849 | bayes_pls_golite062009 |
| guanylate kinase activity | 1.80396483614769 | bayes_pls_golite062009 |
| kinase activity | 1.25975935442248 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.1074378525403 | bayes_pls_golite062009 |
| structural molecule activity | 0.814823288934305 | bayes_pls_golite062009 |
| transferase activity | 0.771251973608877 | bayes_pls_golite062009 |
| protein domain specific binding | 0.683298345987 | bayes_pls_golite062009 |
| receptor binding | 0.463189293111534 | bayes_pls_golite062009 |
| catalytic activity | 0.304516551414824 | bayes_pls_golite062009 |
|
Region A: Residues: [91-204] |
1 11 21 31 41 51
| | | | | |
1 ADFIKSSNLN RNCAYEFNND ASSNQTNQSA LNQNPIANNV SAQAQAEALS RTFKSELEEI 60
61 LNQRMRIESD TENAKEPTVE QQQKQQQAQQ RSSRSPQQQN PQQQQGSKSR SGSQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [205-321] |
1 11 21 31 41 51
| | | | | |
1 TVNGDDSWLY EDIQLERGNS GLGFSIAGGT DNPHIGTDTS IYITKLISGG AAAADGRLSI 60
61 NDIIVSVNDV SVVDVPHASA VDALKKAGNV VKLHVKRKRG TATTPAAGSA AGDARDS
|
| Detection Method: | |
| Confidence: | 23.0 |
| Match: | 1tp3A |
| Description: | PDZ3 domain of PSD-95 protein complexed with KKETPV peptide ligand |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [322-478] |
1 11 21 31 41 51
| | | | | |
1 AASGPKVIEI DLVKGGKGLG FSIAGGIGNQ HIPGDNGIYV TKLMDGGAAQ VDGRLSIGDK 60
61 LIAVRTNGSE KNLENVTHEL AVATLKSITD KVTLIIGKTQ HLTTSASGGG GGGLSSGQQL 120
121 SQSQSQLATS QSQSQVHQQQ HATPMVNSQS TEPGSRY
|
| Detection Method: | |
| Confidence: | 3.83 |
| Match: | 1z87A |
| Description: | solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [479-603] |
1 11 21 31 41 51
| | | | | |
1 ASTNVLAAVP PGTPRAVSTE DITREPRTIT IQKGPQGLGF NIVGGEDGQG IYVSFILAGG 60
61 PADLGSELKR GDQLLSVNNV NLTHATHEEA AQALKTSGGV VTLLAQYRPE EYNRFEARIQ 120
121 ELKQQ
|
| Detection Method: | |
| Confidence: | 9.39794 |
| Match: | 1wh1A |
| Description: | Solution structure of the fourth PDZ domain of KIAA1095 protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleotide kinase activity | 3.8480280652637 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.60106431937699 | bayes_pls_golite062009 |
| protein binding | 3.40921081688513 | bayes_pls_golite062009 |
| phosphotransferase activity, phosphate group as acceptor | 3.36137139211375 | bayes_pls_golite062009 |
| binding | 3.2595117613307 | bayes_pls_golite062009 |
| nucleobase, nucleoside, nucleotide kinase activity | 3.03529700765506 | bayes_pls_golite062009 |
| actin binding | 2.67980594800151 | bayes_pls_golite062009 |
| structural constituent of muscle | 2.51309387684177 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.46961513049145 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.91543407181272 | bayes_pls_golite062009 |
| guanylate kinase activity | 1.70730560221787 | bayes_pls_golite062009 |
| molecular transducer activity | 1.51162321843898 | bayes_pls_golite062009 |
| signal transducer activity | 1.51162321843898 | bayes_pls_golite062009 |
| PDZ domain binding | 1.4161955255054 | bayes_pls_golite062009 |
| transcription regulator activity | 1.37626136403014 | bayes_pls_golite062009 |
| transporter activity | 1.18978519116375 | bayes_pls_golite062009 |
| calcium channel regulator activity | 1.14774855449005 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.07211582292329 | bayes_pls_golite062009 |
| actin filament binding | 0.949031442754707 | bayes_pls_golite062009 |
| structural molecule activity | 0.906026957959903 | bayes_pls_golite062009 |
| kinase activity | 0.905413424946741 | bayes_pls_golite062009 |
| receptor binding | 0.867295068429704 | bayes_pls_golite062009 |
| transcription activator activity | 0.857273718710708 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.755223974149211 | bayes_pls_golite062009 |
| beta-catenin binding | 0.740091060781601 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.729941790230954 | bayes_pls_golite062009 |
| protein domain specific binding | 0.64214865642772 | bayes_pls_golite062009 |
| protein kinase binding | 0.54934142458843 | bayes_pls_golite062009 |
| kinase binding | 0.541050170070789 | bayes_pls_golite062009 |
| myosin binding | 0.52327780808244 | bayes_pls_golite062009 |
| enzyme binding | 0.46071739042312 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.403457741099606 | bayes_pls_golite062009 |
| transferase activity | 0.33240304839436 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.252733105474942 | bayes_pls_golite062009 |
| phosphatase binding | 0.24515474358339 | bayes_pls_golite062009 |
| G-protein-coupled receptor binding | 0.192512046402557 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.182094987832726 | bayes_pls_golite062009 |
| neurexin binding | 0.146752265271612 | bayes_pls_golite062009 |
|
Region A: Residues: [604-970] |
1 11 21 31 41 51
| | | | | |
1 AALGAGGSGT LLRTTQKRSL YVRALFDYDP NRDDGLPSRG LPFKHGDILH VTNASDDEWW 60
61 QARRVLGDNE DEQIGIVPSK RRWERKMRAR DRSVKFQGHA AANNNLDKQS TLDRKKKNFT 120
121 FSRKFPFMKS RDEKNEDGSD QEPFMLCYTQ DDANAEGASE ENVLSYEAVQ RLSINYTRPV 180
181 IILGPLKDRI NDDLISEYPD KFGSCVPHTT RPKREYEVDG RDYHFVSSRE QMERDIQNHL 240
241 FIEAGQYNDN LYGTSVASVR EVAEKGKHCI LDVSGNAIKR LQVAQLYPVA VFIKPKSVDS 300
301 VMEMNRRMTE EQAKKTYERA IKMEQEFGEY FTGVVQGDTI EEIYSKVKSM IWSQSGPTIW 360
361 VPSKESL
|
| Detection Method: | |
| Confidence: | 57.154902 |
| Match: | 1kjwA |
| Description: | Psd-95; Guanylate kinase-like domain of Psd-95 |
Matching Structure (courtesy of the PDB): |
|
