YRC Public Data Repository - Protein Structure Prediction

Protein:	DEF_MYCTU
Organism:	Mycobacterium tuberculosis
Length:	197 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEF_MYCTU.

Description	E-value	Query Range	Subject Range
gi\|90195355, gi\|... - gi\|90205918\|ref\|ZP_01208556.1\| Peptide deformylase [Mycobacterium vanbaalenii PYR-1], gi\|90195355\|gb...	274.0	[0..1]	[197..34]
DEF_MYCBO - Peptide deformylase OS=Mycobacterium bovis GN=def PE=3 SV=1 DEF_MYCBO - Peptide deformylase OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) GN=def PE=3 SV=1	272.0	[0..1]	[197..1]
DEF_MYCPA - Peptide deformylase OS=Mycobacterium paratuberculosis GN=def PE=3 SV=1 gi\|254777164 - gi\|254777164\|ref\|ZP_05218680.1\| peptide deformylase [Mycobacterium avium subsp. avium ATCC 25291] DEF_MYCPA - Peptide deformylase OS=Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) GN=def PE=3 SV=1	271.0	[0..1]	[197..1]
DEF_MYCSJ - Peptide deformylase OS=Mycobacterium sp. (strain JLS) GN=def PE=3 SV=1 DEF_MYCSS - Peptide deformylase OS=Mycobacterium sp. (strain MCS) GN=def PE=3 SV=1 DEF_MYCSK - Peptide deformylase OS=Mycobacterium sp. (strain KMS) GN=def PE=3 SV=1	261.0	[0..1]	[197..1]
DEF_MYCGI - Peptide deformylase OS=Mycobacterium gilvum (strain PYR-GCK) GN=def PE=3 SV=1	260.0	[0..1]	[197..1]
DEF_MYCLE - Peptide deformylase OS=Mycobacterium leprae GN=def PE=3 SV=1 DEF_MYCLE - Peptide deformylase OS=Mycobacterium leprae (strain TN) GN=def PE=3 SV=1 DEF_MYCLB - Peptide deformylase OS=Mycobacterium leprae (strain Br4923) GN=def PE=3 SV=1	256.0	[0..1]	[196..1]
DEF2_CORGL - Peptide deformylase 2 OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG ... DEF2_CORGL - Peptide deformylase 2 OS=Corynebacterium glutamicum GN=def2 PE=3 SV=1	256.0	[0..1]	[197..1]
DEF2_COREF - Peptide deformylase 2 OS=Corynebacterium efficiens GN=def2 PE=3 SV=1 DEF2_COREF - Peptide deformylase 2 OS=Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189...	253.0	[0..1]	[197..1]
gi\|54018783, gi\|... - gi\|54027275\|ref\|YP_121517.1\| peptide deformylase [Nocardia farcinica IFM 10152], gi\|54018783\|dbj\|BAD...	249.0	[0..1]	[197..1]
gi\|116670982, gi... - gi\|66965251\|ref\|ZP_00412818.1\| Formylmethionine deformylase [Arthrobacter sp. FB24], gi\|66868700\|gb\|...	246.0	[0..1]	[197..1]

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Predicted Domain #1

Region A:
Residues: [1-197]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVVPIRIVG DPVLHTATTP VTVAADGSLP ADLAQLIATM YDTMDAANGV GLAANQIGCS  60
   61 LRLFVYDCAA DRAMTARRRG VVINPVLETS EIPETMPDPD TDDEGCLSVP GESFPTGRAK 120
  121 WARVTGLDAD GSPVSIEGTG LFARMLQHET GHLDGFLYLD RLIGRYARNA KRAVKSHGWG 180
  181 VPGLSWLPGE DPDPFGH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.0
Match:	1n5nA
Description:	Peptide deformylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.58820956037645	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2.29341894440799	bayes_pls_golite062009
peptide deformylase activity	2.09701270257336	bayes_pls_golite062009
hydrolase activity	1.74603757697733	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.59643176725105	bayes_pls_golite062009
formylmethionine deformylase activity	0.90550535791718	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: