YRC Public Data Repository - Protein Structure Prediction

Protein:	DAPB_LISMO
Organism:	Listeria monocytogenes
Length:	263 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAPB_LISMO.

Description	E-value	Query Range	Subject Range
DAPB_LISMF - 4-hydroxy-tetrahydrodipicolinate reductase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=d... gi\|47017791, gi\|... - gi\|47093824\|ref\|ZP_00231569.1\| dihydrodipicolinate reductase [Listeria monocytogenes str. 4b H7858],... gi\|153167747, gi... - gi\|153167747\|ref\|ZP_01927851.1\| dihydrodipicolinate reductase [Listeria monocytogenes FSL N1-017], g... gi\|254877975 - gi\|254877975\|ref\|ZP_05250685.1\| dihydrodipicolinate reductase [Listeria monocytogenes FSL J2-071] gi\|254825598 - gi\|254825598\|ref\|ZP_05230599.1\| dihydrodipicolinate reductase [Listeria monocytogenes FSL J1-194] gi\|255520921 - gi\|255520921\|ref\|ZP_05388158.1\| dihydrodipicolinate reductase [Listeria monocytogenes FSL J1-175]	249.0	[0..1]	[263..1]
DAPB_LISIN - Dihydrodipicolinate reductase OS=Listeria innocua GN=dapB PE=3 SV=1 DAPB_LISIN - 4-hydroxy-tetrahydrodipicolinate reductase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=dap...	248.0	[0..1]	[263..1]
DAPB_GEOKA - 4-hydroxy-tetrahydrodipicolinate reductase OS=Geobacillus kaustophilus (strain HTA426) GN=dapB PE=3 ... DAPB_GEOKA - Dihydrodipicolinate reductase OS=Geobacillus kaustophilus GN=dapB PE=3 SV=1	242.0	[0..1]	[263..3]
gi\|227553357, gi... - gi\|227553357\|ref\|ZP_03983406.1\| dihydrodipicolinate reductase [Enterococcus faecalis HH22], gi\|22717... gi\|229545828, gi... - gi\|229545828\|ref\|ZP_04434553.1\| dihydrodipicolinate reductase [Enterococcus faecalis TX1332], gi\|229... DAPB_ENTFA - Dihydrodipicolinate reductase OS=Enterococcus faecalis GN=dapB PE=3 SV=1 gi\|227073800, gi... - gi\|227518747\|ref\|ZP_03948796.1\| dihydrodipicolinate reductase [Enterococcus faecalis TX0104], gi\|227... gi\|229304933, gi... - gi\|229550020\|ref\|ZP_04438745.1\| dihydrodipicolinate reductase [Enterococcus faecalis ATCC 29200], gi... DAPB_ENTFA - 4-hydroxy-tetrahydrodipicolinate reductase OS=Enterococcus faecalis (strain ATCC 700802 / V583) GN=d...	241.0	[0..1]	[262..2]
gi\|86605985 - gi\|86605985\|ref\|YP_474748.1\| dihydrodipicolinate reductase [Cyanobacteria bacterium Yellowstone A-Pr... gi\|86554527, gi\|... - gi\|86605985\|ref\|YP_474748.1\| dihydrodipicolinate reductase [Synechococcus sp. JA-3-3Ab], gi\|86554527...	237.0	[0..1]	[262..26]
DAPB_BACHD - Dihydrodipicolinate reductase OS=Bacillus halodurans GN=dapB PE=3 SV=1 DAPB_BACHD - 4-hydroxy-tetrahydrodipicolinate reductase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 /...	236.0	[0..1]	[263..2]
DAPB_HAES1 - 4-hydroxy-tetrahydrodipicolinate reductase OS=Haemophilus somnus (strain 129Pt) GN=dapB PE=3 SV=1	236.0	[0..1]	[263..3]
gi\|86556945, gi\|... - gi\|86608403\|ref\|YP_477165.1\| dihydrodipicolinate reductase [Synechococcus sp. JA-2-3B'a(2-13)], gi\|8... gi\|86608403 - gi\|86608403\|ref\|YP_477165.1\| dihydrodipicolinate reductase [Cyanobacteria bacterium Yellowstone B-Pr...	236.0	[0..1]	[262..11]
DAPB_ANAVT - 4-hydroxy-tetrahydrodipicolinate reductase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=...	235.0	[0..1]	[262..7]
DAPB_NOSS1 - 4-hydroxy-tetrahydrodipicolinate reductase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=dapB PE=3 ... gi\|25284510 - pir\|\|AG2123 dihydrodipicolinate reductase [imported] - Nostoc sp. (strain PCC 7120)	235.0	[0..1]	[262..7]

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Predicted Domain #1

Region A:
Residues: [1-263]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVAVSGFKG RMGHEVVKTV LREADLELVA VLDHEPKEKN INEMVEFSSL DVPVFGNLSE  60
   61 MLEEIKPDCV VDFTTPKVGY SNTKTILEHG VRAVVGTTGF TPEQISELRT IAESKKIGAL 120
  121 IAPNFAVGAV LMMQFAQKAA KYFPNVEIIE LHHDNKLDAP SGTGVKTAEM MAETREFVKQ 180
  181 GAADEVELIE GARGAEYEGM RIHSVRLPGL VAHQEVIFGA EGQGLTIRHD SYDRISFMSG 240
  241 VALSVRKTKE LETLIYGLEN ILD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.0
Match:	1c3vA
Description:	DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.60548927745815	bayes_pls_golite062009
catalytic activity	2.54843319568228	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.54909195188343	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.841370849960815	bayes_pls_golite062009
saccharopine dehydrogenase activity	0.495113665163626	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.0651785123513661	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: