YRC Public Data Repository - Protein Structure Prediction

Protein:	CYOC_ECOLI
Organism:	Escherichia coli
Length:	204 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYOC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71657945, gi\|... - gi\|71657945\|ref\|YP_272021.1\| cytochrome c oxidase subunit III [Oreochromis mossambicus], gi\|51011729...	232.0	[0..10]	[203..62]
gi\|51235011, gi\|... - gi\|51235011\|ref\|YP_063501.1\| cytochrome c oxidase subunit III [Carassius auratus x Cyprinus carpio],... gi\|55338285, gi\|... - gi\|55338285\|ref\|YP_133899.1\| cytochrome c oxidase subunit III [Carassius auratus x Cyprinus carpio x... COX3_CYPCA - Cytochrome c oxidase subunit 3 OS=Cyprinus carpio GN=mt-co3 PE=2 SV=2 gi\|56798135, gi\|... - gi\|56912174\|ref\|YP_173342.1\| cytochrome c oxidase subunit III [Carassius auratus auratus], gi\|567981... gi\|254033652, gi... - gi\|254033652\|ref\|YP_003058371.1\| cytochrome c oxidase subunit III [natural gynogenetic Carassius aur...	232.0	[0..10]	[203..62]
gi\|44887482, gi\|... - gi\|71658043\|ref\|YP_271995.1\| cytochrome c oxidase subunit III [Cobitis sinensis], gi\|44887482\|gb\|AAS...	231.0	[0..10]	[203..62]
gi\|88759265, gi\|... - gi\|89257267\|ref\|YP_514716.1\| cytochrome c oxidase subunit III [Denticeps clupeoides], gi\|88759265\|db...	231.0	[0..10]	[203..62]
gi\|62526646, gi\|... - gi\|62526646\|gb\|AAX84697.1\| cytochrome oxidase subunit III [Takifugu fasciatus], gi\|62526404\|gb\|AAX84... gi\|215422650, gi... - gi\|215979700\|ref\|YP_002333199.1\| cytochrome c oxidase subunit III [Takifugu xanthopterus], gi\|215422... gi\|215979686, gi... - gi\|215979686\|ref\|YP_002333186.1\| cytochrome c oxidase subunit III [Takifugu vermicularis], gi\|215422... gi\|215422566, gi... - gi\|215979616\|ref\|YP_002333121.1\| cytochrome c oxidase subunit III [Takifugu obscurus], gi\|215422566\|...	231.0	[0..10]	[203..62]
gi\|86604625, gi\|... - gi\|86604625\|dbj\|BAE79210.1\| cytochrome c oxidase subunit III [Takifugu rubripes], gi\|23397373\|ref\|NP... gi\|215422664, gi... - gi\|215979714\|ref\|YP_002333212.1\| cytochrome c oxidase subunit III [Takifugu chinensis], gi\|215422664...	231.0	[0..10]	[203..62]
gi\|16357381, gi\|... - gi\|16357381\|ref\|NP_443690.1\| cytochrome c oxidase subunit III [Helicolenus hilgendorfi], gi\|16267291...	231.0	[0..10]	[203..62]
gi\|110238764 - gi\|110238764\|dbj\|BAE97655.1\| cytochrome oxidase subunit 3 [Cyprinus carpio] COX3_CARAU - Cytochrome c oxidase subunit 3 OS=Carassius auratus GN=mt-co3 PE=2 SV=2 gi\|119365174, gi... - gi\|119365174\|ref\|YP_913425.1\| cytochrome c oxidase subunit III [Barbonymus gonionotus], gi\|119225114...	230.0	[0..10]	[203..62]
gi\|25057301, gi\|... - gi\|25057301\|ref\|NP_739626.1\| cytochrome c oxidase subunit III [Aphredoderus sayanus], gi\|25005488\|db...	230.0	[0..10]	[203..62]
gi\|25006159, gi\|... - gi\|25057931\|ref\|NP_740146.1\| cytochrome c oxidase subunit III [Salarias fasciatus], gi\|25006159\|dbj\|...	230.0	[0..10]	[203..62]

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Predicted Domain #1

Region A:
Residues: [1-204]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATDTLTHAT AHAHEHGHHD AGGTKIFGFW IYLMSDCILF SILFATYAVL VNGTAGGPTG  60
   61 KDIFELPFVL VETFLLLFSS ITYGMAAIAM YKNNKSQVIS WLALTWLFGA GFIGMEIYEF 120
  121 HHLIVNGMGP DRSGFLSAFF ALVGTHGLHV TSGLIWMAVL MVQIARRGLT STNRTRIMCL 180
  181 SLFWHFLDVV WICVFTVVYL MGAM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.522879
Match:	1fftC
Description:	Cytochrome O ubiquinol oxidase, subunit III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transmembrane transporter activity	8.59128089167986	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	6.88271413040221	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	6.58538119091174	bayes_pls_golite062009
cation transmembrane transporter activity	6.45649160474673	bayes_pls_golite062009
ion transmembrane transporter activity	6.3484316712663	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.97318568679269	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.91828857375608	bayes_pls_golite062009
heme-copper terminal oxidase activity	5.83100344847255	bayes_pls_golite062009
cytochrome o ubiquinol oxidase activity	5.57652284753906	bayes_pls_golite062009
cytochrome-c oxidase activity	4.7931528448557	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	4.7931528448557	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	4.7931528448557	bayes_pls_golite062009
transporter activity	4.25438846058626	bayes_pls_golite062009
transmembrane transporter activity	4.17164895597342	bayes_pls_golite062009
substrate-specific transporter activity	4.04860232618097	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	3.26454642730214	bayes_pls_golite062009
oxidoreductase activity	2.87095049256457	bayes_pls_golite062009
catalytic activity	1.98531969314183	bayes_pls_golite062009
active transmembrane transporter activity	0.371119126778133	bayes_pls_golite062009
primary active transmembrane transporter activity	0.361032852452888	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: