YRC Public Data Repository - Protein Structure Prediction

Protein:	CYC_CANFA
Organism:	Canis lupus familiaris
Length:	104 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYC_CANFA.

Description	E-value	Query Range	Subject Range
gi\|229351 - gi\|229351\|prf\|\|711086A cytochrome c	148.0	[0..1]	[104..1]
CYC_SCHGR - (P00040) Cytochrome c	148.0	[0..1]	[103..5]
CYC_CYPCA - (P00026) Cytochrome c iso-1/iso-2	148.0	[0..1]	[102..1]
CYC_HIPAM - (P00007) Cytochrome c	147.0	[0..1]	[104..1]
gi\|30178199, gi\|... - gi\|31202411\|ref\|XP_310154.1\| AGAP009537-PA [Anopheles gambiae str. PEST], gi\|30178199\|gb\|EAA05914.2\|... AGAP009537-PA - cytochrome c\|protein_coding\|3R:35606586:35606912:1\|gene:AGAP009537	146.0	[0..1]	[103..6]
CYC_DANRE - Cytochrome c OS=Danio rerio GN=cyc PE=3 SV=3	146.0	[0..1]	[102..2]
gi\|89272026 - gi\|89272026\|emb\|CAJ83237.1\| cytochrome c, somatic [Xenopus tropicalis]	146.0	[0..1]	[104..9]
CYC_CANLF - Cytochrome c OS=Canis lupus familiaris GN=CYCS PE=1 SV=2	146.0	[0..1]	[104..2]
gi\|4139756, gi\|1... - gi\|809143\|pdb\|1HRC\| Chain , Cytochrome C, gi\|4139756\|pdb\|1WEJ\|F Chain F, Igg1 Fab Fragment (Of E8 ...	146.0	[0..1]	[104..2]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDVEKGKKIF VQKCAQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGFSYTD ANKNKGITWG  60
   61 EETLMEYLEN PKKYIPGTKM IFAGIKKTGE RADLIAYLKK ATKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.0
Match:	1akkA
Description:	SOLUTION STRUCTURE OF OXIDIZED HORSE HEART CYTOCHROME C, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	7.77694826742571	bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity	7.77694826742571	bayes_pls_golite062009
electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity	5.3228546115966	bayes_pls_golite062009
electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	4.97969104367667	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	4.83198573144889	bayes_pls_golite062009
oxidoreductase activity	4.80453374142732	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	4.69221581420605	bayes_pls_golite062009
electron carrier activity	4.50051625202265	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	4.39250939893637	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	4.11195915185456	bayes_pls_golite062009
phosphoprotein phosphatase activity	3.07137767450073	bayes_pls_golite062009
protein serine/threonine phosphatase activity	3.05900853572871	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.75675744166378	bayes_pls_golite062009
peroxidase activity	2.75675744166378	bayes_pls_golite062009
antioxidant activity	2.60087791856484	bayes_pls_golite062009
phosphatase activity	2.58257339159796	bayes_pls_golite062009
phosphoric ester hydrolase activity	2.48742191899955	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.67966224915812	bayes_pls_golite062009
binding	1.60003804759784	bayes_pls_golite062009
transporter activity	1.44083733311658	bayes_pls_golite062009
protein binding	1.33090393131805	bayes_pls_golite062009
transmembrane transporter activity	1.28161778948702	bayes_pls_golite062009
substrate-specific transporter activity	1.15573917988688	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.01443199299167	bayes_pls_golite062009
ion transmembrane transporter activity	0.881486298760893	bayes_pls_golite062009
cation transmembrane transporter activity	0.783993292151034	bayes_pls_golite062009
hydrolase activity	0.624991704964657	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: