YRC Public Data Repository - Protein Structure Prediction

Protein:	CYBH_ECOLI
Organism:	Escherichia coli
Length:	235 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYBH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|115517201, gi... - gi\|77738799\|ref\|ZP_00807292.1\| Nickel-dependent hydrogenase b-type cytochrome subunit [Rhodopseudomo...	162.0	[0..3]	[229..16]
gi\|226721974, gi... - gi\|67157883\|ref\|ZP_00419028.1\| Nickel-dependent hydrogenase b-type cytochrome subunit [Azotobacter v... CYBH_AZOVI - Probable Ni/Fe-hydrogenase B-type cytochrome subunit OS=Azotobacter vinelandii GN=hoxZ PE=3 SV=1	162.0	[0..2]	[229..13]
gi\|89082043, gi\|... - gi\|89093647\|ref\|ZP_01166594.1\| Nickel-dependent hydrogenase b-type cytochrome subunit [Oceanospirill...	162.0	[0..5]	[229..21]
gi\|78494088, gi\|... - gi\|90425254\|ref\|YP_533624.1\| nickel-dependent hydrogenase b-type cytochrome subunit [Rhodopseudomona...	160.0	[0..3]	[227..16]
gi\|1073102, gi\|4... - gi\|408902\|gb\|AAA64447.1\| hydrogenase-related protein [Azotobacter chroococcum], pir\|\|S53656 hydrogen... CYBH_AZOCH - Probable Ni/Fe-hydrogenase B-type cytochrome subunit OS=Azotobacter chroococcum mcd 1 GN=hupZ PE=3 S...	159.0	[0..2]	[229..13]
gi\|47177022\|ref\|... - HoxZ [Oligotropha carboxidovorans], HoxZ [Oligotropha carboxidovorans] gi\|47177022, gi\|... - gi\|47177022\|ref\|YP_015633.1\| HoxZ [Oligotropha carboxidovorans OM5], gi\|47115413\|emb\|CAG28466.1\| Hox...	158.0	[0..5]	[229..23]
gi\|192283315, gi... - gi\|192289566\|ref\|YP_001990171.1\| Ni/Fe-hydrogenase, b-type cytochrome subunit [Rhodopseudomonas palu... hupC - hupC Ni/Fe-hydrogenase 1 B-type cytochrome subunit 1067114:1067842 forward MW:28030	158.0	[0..3]	[229..17]
CYBH_RHOCA - Probable Ni/Fe-hydrogenase B-type cytochrome subunit OS=Rhodobacter capsulatus GN=hupC PE=1 SV=1	158.0	[0..3]	[228..35]
gi\|91975644, gi\|... - gi\|91975644\|ref\|YP_568303.1\| nickel-dependent hydrogenase b-type cytochrome subunit [Rhodopseudomona...	158.0	[0..3]	[229..17]
gi\|94310239, gi\|... - gi\|94310239\|ref\|YP_583449.1\| nickel-dependent hydrogenase b-type cytochrome subunit [Ralstonia metal...	158.0	[0..5]	[226..23]

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Predicted Domain #1

Region A:
Residues: [1-235]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQKSDNVVS HYVFEAPVRI WHWLTVLCMA VLMVTGYFIG KPLPSVSGEA TYLFYMGYIR  60
   61 LIHFSAGMVF TVVLLMRIYW AFVGNRYSRE LFIVPVWRKS WWQGVWYEIR WYLFLAKRPS 120
  121 ADIGHNPIAQ AAMFGYFLMS VFMIITGFAL YSEHSQYAIF APFRYVVEFF YWTGGNSMDI 180
  181 HSWHRLGMWL IGAFVIGHVY MALREDIMSD DTVISTMVNG YRSHKFGKIS NKERS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.522879
Match:	1kqfC
Description:	Formate dehydrogenase N, cytochrome (gamma) subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transmembrane transporter activity	4.29455986972274	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	4.14658254808421	bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity	3.64153536514168	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	3.64153536514168	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	3.50341532760587	bayes_pls_golite062009
cation transmembrane transporter activity	3.24971217721974	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	3.24610027021932	bayes_pls_golite062009
ion transmembrane transporter activity	3.0416933490072	bayes_pls_golite062009
electron carrier activity	2.51878542975969	bayes_pls_golite062009
oxidoreductase activity	1.7836019763102	bayes_pls_golite062009
formate dehydrogenase activity	1.59045445940899	bayes_pls_golite062009
catalytic activity	1.19342057724506	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.173080554590997	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.146687943468395	bayes_pls_golite062009
substrate-specific transporter activity	0.0890676728517352	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0525552238787478	bayes_pls_golite062009
binding	0.00724604692107611	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: