YRC Public Data Repository - Protein Structure Prediction

Protein:	CORA_ECOLI
Organism:	Escherichia coli
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CORA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|221564892, gi... - gi\|222055603\|ref\|YP_002537965.1\| magnesium and cobalt transport protein CorA [Geobacter sp. FRC-32],...	260.0	[0..2]	[316..31]
gi\|110550987, gi... - gi\|126178737\|ref\|YP_001046702.1\| magnesium and cobalt transport protein CorA [Methanoculleus marisni...	259.0	[0..2]	[316..21]
gi\|67546254, gi\|... - gi\|67546254\|ref\|ZP_00424169.1\| Magnesium and cobalt transport protein CorA [Burkholderia vietnamiens...	259.0	[0..1]	[316..48]
gi\|83857246, gi\|... - gi\|83857246\|ref\|ZP_00950774.1\| Magnesium and cobalt transport protein [Croceibacter atlanticus HTCC2...	254.0	[0..2]	[316..41]
gi\|116647831, gi... - gi\|67667232\|ref\|ZP_00464461.1\| Magnesium and cobalt transport protein CorA [Burkholderia cenocepacia... gi\|67096513, gi\|... - gi\|67655813\|ref\|ZP_00453198.1\| Magnesium and cobalt transport protein CorA [Burkholderia cenocepacia...	251.0	[0..1]	[316..2]
gi\|84361847 - gi\|84361847\|ref\|ZP_00986488.1\| COG0598: Mg2+ and Co2+ transporters [Burkholderia dolosa AUO158]	251.0	[0..1]	[316..5]
gi\|254245392, gi... - gi\|84357841\|ref\|ZP_00982649.1\| COG0598: Mg2+ and Co2+ transporters [Burkholderia cenocepacia PC184],... gi\|118711973, gi... - gi\|170733078\|ref\|YP_001765025.1\| magnesium and cobalt transport protein CorA [Burkholderia cenocepac... gi\|206560155, gi... - gi\|206560155\|ref\|YP_002230919.1\| putative metal ion transport protein [Burkholderia cenocepacia J231...	250.0	[0..1]	[316..2]
gi\|85544265, gi\|... - gi\|85544267\|pdb\|2BBJ\|F Chain F, Crystal Structure Of The Cora Mg2+ Transporter, gi\|85544266\|pdb\|2BBJ...	250.0	[0..10]	[316..46]
gi\|77967227, gi\|... - gi\|78066482\|ref\|YP_369251.1\| magnesium/cobalt transporter CorA [Burkholderia sp. 383], gi\|77967227\|g...	250.0	[0..1]	[316..2]

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Predicted Domain #1

Region A:
Residues: [1-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSAFQLENN RLTRLEVEES QPLVNAVWID LVEPDDDERL RVQSELGQSL ATRPELEDIE  60
   61 ASARFFEDDD GLHIHSFFFF EDAEDHAGNS TVAFTIRDGR LFTLRERELP AFRLYRMRAR 120
  121 SQSMVDGNAY ELLLDLFETK IEQLADEIEN IYSDLEQLSR VIMEGHQGDE YDEALSTLAE 180
  181 LEDIGWKVRL CLMDTQRALN FLVRKARLPG GQLEQAREIL RDIESLLPHN ESLFQKVNFL 240
  241 MQAAMGFINI EQNRIIKIFS VVSVVFLPPT LVASSYGMNF EFMPELKWSF GYPGAIIFMI 300
  301 LAGLAPYLYF KRKNWL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.39794
Match:	2bbjA
Description:	Crystal structure of the CorA Mg2+ transporter
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
magnesium ion transmembrane transporter activity	7.63785586121898	bayes_pls_golite062009
cobalt ion transmembrane transporter activity	7.48429812485343	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	5.47408292962243	bayes_pls_golite062009
metal ion transmembrane transporter activity	4.27993916398035	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	4.02949149198783	bayes_pls_golite062009
cation transmembrane transporter activity	3.9353435026882	bayes_pls_golite062009
ion transmembrane transporter activity	3.87152688974328	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.60691302970128	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	3.57322088679472	bayes_pls_golite062009
transporter activity	2.16348856338652	bayes_pls_golite062009
transmembrane transporter activity	2.04530161484383	bayes_pls_golite062009
substrate-specific transporter activity	1.79472790754975	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: