YRC Public Data Repository - Protein Structure Prediction

Protein:	CHEY_THEMA
Organism:	Thermotoga maritima
Length:	120 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHEY_THEMA.

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	167.0	[0..2]	[120..104]
gi\|10175779, gi\|... - gi\|15615719\|ref\|NP_244023.1\| two-component response regulator involved in phosphate regulation [Baci... gi\|25300880 - pir\|\|E84044 two-component response regulator involved in phosphate regulation phoP [imported] - Baci...	166.0	[0..1]	[120..1]
gi\|67661867, gi\|... - gi\|67661867\|ref\|ZP_00459158.1\| Response regulator receiver:Transcriptional regulatory protein, C-ter... gi\|67091754, gi\|... - gi\|67660691\|ref\|ZP_00458032.1\| Response regulator receiver:Transcriptional regulatory protein, C-ter...	164.0	[0..1]	[120..95]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	163.0	[0..1]	[120..1]
gi\|47556738, gi\|... - gi\|47566185\|ref\|ZP_00237213.1\| two-component response regulator [Bacillus cereus G9241], gi\|47556738...	163.0	[0..1]	[120..1]
gi\|89897369, gi\|... - gi\|89897369\|ref\|YP_520856.1\| hypothetical protein DSY4623 [Desulfitobacterium hafniense Y51], gi\|893...	163.0	[0..3]	[120..1]
gi\|143328 - gi\|143328\|gb\|AAA22661.1\| phoP protein (put.); putative	162.0	[0..1]	[120..1]
PHOP_BACSU - Alkaline phosphatase synthesis transcriptional regulatory protein phoP OS=Bacillus subtilis GN=phoP ... gi\|2635376, gi\|1... - gi\|2635376\|emb\|CAB14871.1\| two-component response regulator [Bacillus subtilis subsp. subtilis str. ...	162.0	[0..1]	[120..1]

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Predicted Domain #1

Region A:
Residues: [1-120]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKRVLIVDD AAFMRMMLKD IITKAGYEVA GEATNGREAV EKYKELKPDI VTMDITMPEM  60
   61 NGIDAIKEIM KIDPNAKIIV CSAMGQQAMV IEAIKAGAKD FIVKPFQPSR VVEALNKVSK 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.522879
Match:	1tmyA
Description:	CHEY FROM THERMOTOGA MARITIMA (APO-I)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009
protein kinase activity	0.73223373303195	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.483665536682372	bayes_pls_golite062009
kinase activity	0.354820297776097	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126415734125785	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: