YRC Public Data Repository - Protein Structure Prediction

Protein:	AVTA_ECOLI
Organism:	Escherichia coli
Length:	417 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AVTA_ECOLI.

Description	E-value	Query Range	Subject Range
AAT1_BACSU - Aspartate aminotransferase OS=Bacillus subtilis GN=aspB PE=3 SV=1 AAT1_BACSU - Aspartate aminotransferase OS=Bacillus subtilis (strain 168) GN=aspB PE=3 SV=1 gi\|221314475 - gi\|221314475\|ref\|ZP_03596280.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. N... gi\|221319397 - gi\|221319397\|ref\|ZP_03600691.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. J... gi\|221323673 - gi\|221323673\|ref\|ZP_03604967.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. S...	328.0	[0..1]	[412..1]
AAT_AQUAE - Aspartate aminotransferase OS=Aquifex aeolicus (strain VF5) GN=aspC PE=3 SV=1 AAT_AQUAE - Aspartate aminotransferase OS=Aquifex aeolicus GN=aspC PE=3 SV=1	325.0	[0..6]	[411..5]
AAT_PYRAB - Aspartate aminotransferase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=aspC PE=3 SV=1 AAT_PYRAB - Aspartate aminotransferase OS=Pyrococcus abyssi GN=aspC PE=3 SV=1	323.0	[0..1]	[411..1]
gi\|48895332, gi\|... - gi\|71675283\|ref\|ZP_00673028.1\| Aminotransferase, class I and II [Trichodesmium erythraeum IMS101], g...	323.0	[0..1]	[411..1]
gi\|67853694, gi\|... - gi\|67924467\|ref\|ZP_00517891.1\| Aminotransferase, class I and II [Crocosphaera watsonii WH 8501], gi\|...	323.0	[0..3]	[411..1]
gi\|82500308, gi\|... - gi\|82500308\|ref\|ZP_00885728.1\| aspartate aminotransferase [Caldicellulosiruptor saccharolyticus DSM ...	321.0	[0..1]	[417..1]
gi\|18977625, gi\|... - gi\|18977625\|ref\|NP_578982.1\| aspartate aminotransferase [Pyrococcus furiosus DSM 3638], gi\|18893347\|...	320.0	[0..1]	[411..1]
gi\|196253921, gi... - gi\|196253921\|ref\|ZP_03152522.1\| aminotransferase class I and II [Clostridium thermocellum DSM 4150],... gi\|67849411, gi\|... - gi\|67916633\|ref\|ZP_00510335.1\| Aminotransferase, class I and II [Clostridium thermocellum ATCC 27405...	320.0	[0..1]	[409..1]
gi\|57158807, gi\|... - gi\|57640483\|ref\|YP_182961.1\| aspartate aminotransferase [Thermococcus kodakarensis KOD1], gi\|5715880...	320.0	[0..1]	[411..1]
gi\|228656558, gi... - gi\|229126958\|ref\|ZP_04255969.1\| Aspartate aminotransferase [Bacillus cereus BDRD-Cer4], gi\|228656558... gi\|29895237, gi\|... - gi\|30019693\|ref\|NP_831324.1\| aspartate aminotransferase [Bacillus cereus ATCC 14579], gi\|29895237\|gb...	319.0	[0..1]	[411..1]

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Predicted Domain #1

Region A:
Residues: [1-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTFSLFGDKF TRHSGITLLM EDLNDGLRTP GAIMLGGGNP AQIPEMQDYF QTLLTDMLES  60
   61 GKATDALCNY DGPQGKTELL TLLAGMLREK LGWDIEPQNI ALTNGSQSAF FYLFNLFAGR 120
  121 RADGRVKKVL FPLAPEYIGY ADAGLEEDLF VSARPNIELL PEGQFKYHVD FEHLHIGEET 180
  181 GMICVSRPTN PTGNVITDEE LLKLDALANQ HGIPLVIDNA YGVPFPGIIF SEARPLWNPN 240
  241 IVLCMSLSKL GLPGSRCGII IANEKIITAI TNMNGIISLA PGGIGPAMMC EMIKRNDLLR 300
  301 LSETVIKPFY YQRVQETIAI IRRYLPENRC LIHKPEGAIF LWLWFKDLPI TTKQLYQRLK 360
  361 ARGVLMVPGH NFFPGLDKPW PHTHQCMRMN YVPEPEKIEA GVKILAEEIE RAWAESH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.69897
Match:	1j32A
Description:	Aspartate aminotransferase, AAT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.66922865456094	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.85532625717753	bayes_pls_golite062009
transaminase activity	1.83482013760414	bayes_pls_golite062009
transferase activity	0.93810038069762	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.42387060098718	bayes_pls_golite062009
L-alanine:2-oxoglutarate aminotransferase activity	0.22825246550961	bayes_pls_golite062009
alanine-oxo-acid transaminase activity	0.22825246550961	bayes_pls_golite062009
lyase activity	0.0414385380659299	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: