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View Structure Prediction Details

Protein: ASNA_STRPY
Organism: Streptococcus pyogenes
Length: 330 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASNA_STRPY.

Description E-value Query
Range		 Subject
Range
ASNA_STRP8 - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M18 (strain MGAS8232) GN=asnA PE=3 SV=1
ASNA_STRPB - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M12 (strain MGAS2096) GN=asnA PE=3 SV=1
ASNA_STRPQ - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M3 (strain SSI-1) GN=asnA PE=3 SV=1
ASNA_STRP3 - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) GN=a...
ASNA_STRPC - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M12 (strain MGAS9429) GN=asnA PE=3 SV=1
ASNA_STRPM - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M28 (strain MGAS6180) GN=asnA PE=3 SV=1
ASNA_STRPF - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M4 (strain MGAS10750) GN=asnA PE=3 SV=1
ASNA_STRPM - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M28 GN=asnA PE=3 SV=1
ASNA_STRP3 - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M3 GN=asnA PE=3 SV=1
ASNA_STRP8 - Aspartate--ammonia ligase OS=Streptococcus pyogenes serotype M18 GN=asnA PE=3 SV=1
 601.0 [0..1] [330..1]

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Predicted Domain #1
Region A:
Residues: [1-330] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKSFIHQQE EISFVKNTFT QYLIAKLDVV EVQGPILSRV GDGMQDNLSG TENPVSVNVL  60
   61 KIPNATFEVV HSLAKWKRHT LARFGFNEGE GLVVNMKALR PDEDSLDQTH SVYVDQWDWE 120
  121 KVIPDGKRNL AYLKETVETI YKVIRLTELA VEARYDIEAV LPKKITFIHT EELVAKYPDL 180
  181 TPKERENAIT KEFGAVFLIG IGGVLPDGKP HDGRAPDYDD WTTETENGYH GLNGDILVWN 240
  241 DQLGSAFELS SMGIRVDEEA LKRQVEMTGD QDRLGFDWHK SLLNGLFPLT IGGGIGQSRM 300
  301 VMFLLRKQHI GEVQTSVWPQ EVRDSYDNIL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 160.0
Match: 11asA
Description: Asparagine synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 3.95982081475525 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.95982081475525 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 3.9592004812151 bayes_pls_golite062009
ligase activity 3.05852492533937 bayes_pls_golite062009
catalytic activity 2.36416267096403 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 0.27932659689192 bayes_pls_golite062009
serine-tRNA ligase activity 0.15245558407217 bayes_pls_golite062009
threonine-tRNA ligase activity 0.0873863095068197 bayes_pls_golite062009
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