YRC Public Data Repository - Protein Structure Prediction

Protein:	AROD_ECOLI
Organism:	Escherichia coli
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AROD_ECOLI.

Description	E-value	Query Range	Subject Range
AROD_SALTY - 3-dehydroquinate dehydratase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=aroD... AROD_SALTY - 3-dehydroquinate dehydratase OS=Salmonella typhimurium GN=aroD PE=1 SV=1 AROD_SALTY - 3-dehydroquinate dehydratase OS=Salmonella typhimurium GN=aroD PE=3 SV=1 lcl\|NC_016856.1_... - [gene=aroD] [protein=3-dehydroquinate dehydratase] [protein_id=YP_005237224.1] [location=complement(...	306.0	[0..1]	[252..1]
AROD_SALPB - 3-dehydroquinate dehydratase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=aroD PE=3 SV... AROD_SALEP - 3-dehydroquinate dehydratase OS=Salmonella enteritidis PT4 (strain P125109) GN=aroD PE=3 SV=1 AROD_SALEN - 3-dehydroquinate dehydratase OS=Salmonella enteritidis GN=aroD PE=3 SV=1 AROD_SALG2 - 3-dehydroquinate dehydratase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=aroD PE=3 SV=1 AROD_SALEN - 3-dehydroquinate dehydratase OS=Salmonella enteritidis GN=aroD PE=3 SV=1 gi\|195634099, gi... - gi\|195634099\|gb\|EDX52451.1\| 3-dehydroquinate dehydratase, type I [Salmonella enterica subsp. enteric... gi\|205339546, gi... - gi\|205339546\|gb\|EDZ26310.1\| 3-dehydroquinate dehydratase, type I [Salmonella enterica subsp. enteric... gi\|197287773, gi... - gi\|197287773\|gb\|EDY27163.1\| 3-dehydroquinate dehydratase, type I [Salmonella enterica subsp. enteric... gi\|200390517, gi... - gi\|200390517\|ref\|ZP_03217128.1\| 3-dehydroquinate dehydratase, type I [Salmonella enterica subsp. ent... AROD_SALDC - 3-dehydroquinate dehydratase OS=Salmonella dublin (strain CT_02021853) GN=aroD PE=3 SV=1 AROD_SALPB - 3-dehydroquinate dehydratase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=aroD PE=3 SV... AROD_SALSV - 3-dehydroquinate dehydratase OS=Salmonella schwarzengrund (strain CVM19633) GN=aroD PE=3 SV=1 AROD_SALHS - 3-dehydroquinate dehydratase OS=Salmonella heidelberg (strain SL476) GN=aroD PE=3 SV=1	305.0	[0..1]	[252..1]
gi\|192957801, gi... - gi\|75236851\|ref\|ZP_00720922.1\| COG0710: 3-dehydroquinate dehydratase [Escherichia coli E110019], gi\|... gi\|194412461, gi... - gi\|75209263\|ref\|ZP_00709507.1\| COG0710: 3-dehydroquinate dehydratase [Escherichia coli B171], gi\|194... AROD_ECOSE - 3-dehydroquinate dehydratase OS=Escherichia coli (strain SE11) GN=aroD PE=3 SV=1	304.0	[0..1]	[252..1]
AROD_ECO57 - 3-dehydroquinate dehydratase OS=Escherichia coli O157:H7 GN=aroD PE=3 SV=1 gi\|217328742, gi... - gi\|217328742\|ref\|ZP_03444823.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. ... AROD_ECO5E - 3-dehydroquinate dehydratase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=aroD PE=3 SV=1 gi\|209769082, gi... - pir\|\|D85777 3-dehydroquinate dehydratase [imported] - Escherichia coli (strain O157:H7, substrain E... gi\|208810528, gi... - gi\|208810528\|ref\|ZP_03252404.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. ... gi\|254793310, gi... - gi\|254793310\|ref\|YP_003078147.1\| 3-dehydroquinate dehydratase [Escherichia coli O157:H7 str. TW14359... gi\|12515698, gi\|... - gi\|15802105\|ref\|NP_288127.1\| 3-dehydroquinate dehydratase [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|195937377 - gi\|195937377\|ref\|ZP_03082759.1\| 3-dehydroquinate dehydratase [Escherichia coli O157:H7 str. EC4024] gi\|208818808, gi... - gi\|208818808\|ref\|ZP_03259128.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. ... gi\|208816915, gi... - gi\|208816915\|ref\|ZP_03258035.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. ... gi\|168782105, gi... - gi\|189000241\|gb\|EDU69227.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC40... gi\|187769362, gi... - gi\|187769362\|gb\|EDU33206.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC41... gi\|168800129, gi... - gi\|189377530\|gb\|EDU95946.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC50... gi\|168789827, gi... - gi\|189370589\|gb\|EDU89005.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC86... gi\|168756691, gi... - gi\|189356135\|gb\|EDU74554.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC44... gi\|168751896, gi... - gi\|188014145\|gb\|EDU52267.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC41... gi\|189360635, gi... - gi\|189360635\|gb\|EDU79054.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC44... gi\|168762246, gi... - gi\|189367494\|gb\|EDU85910.1\| 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC45... gi\|13361867, gi\|... - gi\|15831654\|ref\|NP_310427.1\| 3-dehydroquinate dehydratase [Escherichia coli O157:H7 str. Sakai], gi\|...	304.0	[0..1]	[252..1]
gi\|75241427, gi\|... - gi\|75241427\|ref\|ZP_00725278.1\| COG0710: 3-dehydroquinate dehydratase [Escherichia coli F11], gi\|1911... AROD_ECOL5 - 3-dehydroquinate dehydratase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=aroD PE=3 SV=1	304.0	[0..1]	[252..1]
AROD_SALCH - 3-dehydroquinate dehydratase OS=Salmonella choleraesuis GN=aroD PE=3 SV=1 AROD_SALCH - 3-dehydroquinate dehydratase OS=Salmonella choleraesuis GN=aroD PE=3 SV=1 AROD_SALCH - 3-dehydroquinate dehydratase OS=Salmonella choleraesuis (strain SC-B67) GN=aroD PE=3 SV=1	303.0	[0..1]	[252..1]
AROD_SHIB3 - 3-dehydroquinate dehydratase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=aroD PE=...	303.0	[0..1]	[252..1]
AROD_ECOL6 - 3-dehydroquinate dehydratase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=aroD ... AROD_ECOUT - 3-dehydroquinate dehydratase OS=Escherichia coli (strain UTI89 / UPEC) GN=aroD PE=3 SV=1 gi\|227885887, gi... - gi\|227885887\|ref\|ZP_04003692.1\| 3-dehydroquinate dehydratase [Escherichia coli 83972], gi\|227837460\|... AROD_ECOL6 - 3-dehydroquinate dehydratase OS=Escherichia coli O6 GN=aroD PE=3 SV=1 gi\|226900396, gi... - gi\|237705639\|ref\|ZP_04536120.1\| 3-dehydroquinate dehydratase [Escherichia sp. 3_2_53FAA], gi\|2269003... AROD_ECO81 - 3-dehydroquinate dehydratase OS=Escherichia coli O81 (strain ED1a) GN=aroD PE=3 SV=1 sp\|B7US32\|AROD_ECO27 - 3-dehydroquinate dehydratase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=aroD PE=3 SV=1 AROD_ECOK1 - 3-dehydroquinate dehydratase OS=Escherichia coli O1:K1 / APEC GN=aroD PE=3 SV=1 AROD_ECO27 - 3-dehydroquinate dehydratase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=aroD PE=3 SV=1 AROD_ECO45 - 3-dehydroquinate dehydratase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=aroD PE=3 SV=1	303.0	[0..1]	[252..1]
gi\|75228996, gi\|... - gi\|75228996\|ref\|ZP_00715583.1\| COG0710: 3-dehydroquinate dehydratase [Escherichia coli B7A], gi\|1911... AROD_ECO24 - 3-dehydroquinate dehydratase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=aroD PE=3 SV=1	303.0	[0..1]	[252..1]
gi\|193065303, gi... - gi\|75256651\|ref\|ZP_00728268.1\| COG0710: 3-dehydroquinate dehydratase [Escherichia coli E22], gi\|1930...	303.0	[0..1]	[252..1]

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Predicted Domain #1

Region A:
Residues: [1-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTVTVKDLV IGTGAPKIIV SLMAKDIASV KSEALAYREA DFDILEWRVD HYADLSNVES  60
   61 VMAAAKILRE TMPEKPLLFT FRSAKEGGEQ AISTEAYIAL NRAAIDSGLV DMIDLELFTG 120
  121 DDQVKETVAY AHAHDVKVVM SNHDFHKTPE AEEIIARLRK MQSFDADIPK IALMPQSTSD 180
  181 VLTLLAATLE MQEQYADRPI ITMSMAKTGV ISRLAGEVFG SAATFGAVKK ASAPGQISVN 240
  241 DLRTVLTILH QA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.69897
Match:	1gqnA
Description:	Native 3-dehydroquinase from Salmonella typhi
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	3.04075198078553	bayes_pls_golite062009
3-deoxy-7-phosphoheptulonate synthase activity	2.96394105633886	bayes_pls_golite062009
lyase activity	1.40463692440932	bayes_pls_golite062009
dihydrodipicolinate synthase activity	1.2687335039487	bayes_pls_golite062009
oxo-acid-lyase activity	1.10805171525041	bayes_pls_golite062009
carbon-carbon lyase activity	1.00678396839999	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.19603703811218	bayes_pls_golite062009
3-deoxy-8-phosphooctulonate synthase activity	0.11229304382048	bayes_pls_golite062009
carbon-oxygen lyase activity	0.0228214205561801	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: