YRC Public Data Repository - Protein Structure Prediction

Protein:	1A1D_PSEUD
Organism:	Pseudomonas sp. ACP
Length:	338 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for 1A1D_PSEUD.

Description	E-value	Query Range	Subject Range
1A1D_BURXL - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia xenovorans (strain LB400) GN=acdS PE=3 S...	287.0	[0..1]	[338..1]
gi\|9230747 - gi\|9230747\|gb\|AAF85968.1\| ACC deaminase [synthetic construct]	286.0	[0..1]	[338..1]
gi\|254249233, gi... - gi\|84353726\|ref\|ZP_00978652.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ce...	285.0	[0..1]	[338..1]
gi\|75910354, gi\|... - gi\|75910354\|ref\|YP_324650.1\| cystathionine beta-synthase [Anabaena variabilis ATCC 29413], gi\|757040...	284.0	[0..3]	[335..1]
1A1D_BURCH - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia cenocepacia (strain HI2424) GN=acdS PE=3... 1A1D_BURCA - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia cenocepacia (strain AU 1054) GN=acdS PE=...	283.0	[0..1]	[338..1]
1A1D_BURVG - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia vietnamiensis (strain G4 / LMG 22486) GN...	283.0	[0..1]	[338..1]
1A1D_BURCM - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) G...	282.0	[0..1]	[338..1]
gi\|194519296, gi... - gi\|67759377\|ref\|ZP_00498115.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ps... gi\|167915182 - gi\|167915182\|ref\|ZP_02502273.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... 1A1D_BURP1 - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia pseudomallei (strain 1710b) GN=acdS PE=3... gi\|134282514, gi... - gi\|134282514\|ref\|ZP_01769218.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|167723898 - gi\|167723898\|ref\|ZP_02407134.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|167906828 - gi\|167906828\|ref\|ZP_02494033.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|235000322, gi... - gi\|237508117\|ref\|ZP_04520832.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|254301835, gi... - gi\|83676821\|ref\|ZP_00938590.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ps... gi\|67670576, gi\|... - gi\|99909173\|ref\|ZP_01316739.1\| hypothetical protein Bpse1_03003901 [Burkholderia pseudomallei 1655],... gi\|67682732, gi\|... - gi\|90291655\|ref\|ZP_01211278.1\| hypothetical protein Bpse17_02003675 [Burkholderia pseudomallei 1710a... gi\|67753996, gi\|... - gi\|67753996\|ref\|ZP_00492915.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ps...	281.0	[0..1]	[338..1]
gi\|166854037, gi... - gi\|167039797\|ref\|YP_001662782.1\| cysteine synthase A [Thermoanaerobacter sp. X514], gi\|166854037\|gb\|...	280.0	[0..4]	[332..7]
gi\|85062980 - gi\|85062980\|ref\|ZP_01023834.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ma... gi\|87315575, gi\|... - gi\|87315575\|ref\|ZP_01096601.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ma... 1A1D_BURP6 - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia pseudomallei (strain 668) GN=acdS PE=3 S... 1A1D_BURMS - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia mallei (strain SAVP1) GN=acdS PE=3 SV=1 1A1D_BURP0 - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia pseudomallei (strain 1106a) GN=acdS PE=3... gi\|242135809, gi... - gi\|82534916\|ref\|ZP_00893941.1\| hypothetical protein Bpse110_02003797 [Burkholderia pseudomallei 1106... gi\|100914738, gi... - gi\|67635216\|ref\|ZP_00434175.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ma... gi\|67642259, gi\|... - gi\|67642259\|ref\|ZP_00441018.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia mallei GB8 ... 1A1D_BURMA - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia mallei GN=acdS PE=3 SV=1 gi\|254200430, gi... - gi\|83618981\|ref\|ZP_00929427.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ma... 1A1D_BURPS - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia pseudomallei GN=acdS PE=3 SV=1 gi\|194530032, gi... - gi\|83624320\|ref\|ZP_00934570.1\| COG2515: 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia ma... 1A1D_BURMA - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia mallei (strain ATCC 23344) GN=acdS PE=3 ... 1A1D_BURM7 - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia mallei (strain NCTC 10247) GN=acdS PE=3 ... 1A1D_BURM9 - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia mallei (strain NCTC 10229) GN=acdS PE=3 ... 1A1D_BURPS - 1-aminocyclopropane-1-carboxylate deaminase OS=Burkholderia pseudomallei (strain K96243) GN=acdS PE=... gi\|167820042 - gi\|167820042\|ref\|ZP_02451722.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|167828423 - gi\|167828423\|ref\|ZP_02459894.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|243064423, gi... - gi\|243064423\|gb\|EES46609.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia mallei PRL-20]... gi\|167742870 - gi\|167742870\|ref\|ZP_02415644.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|194313073, gi... - gi\|254174015\|ref\|ZP_04880678.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia mallei ATC... gi\|217418495, gi... - gi\|217418495\|ref\|ZP_03450002.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|167898477 - gi\|167898477\|ref\|ZP_02485878.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|167923018 - gi\|167923018\|ref\|ZP_02510109.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall... gi\|225929424, gi... - gi\|226198501\|ref\|ZP_03794068.1\| 1-aminocyclopropane-1-carboxylate deaminase [Burkholderia pseudomall...	279.0	[0..1]	[338..1]

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Predicted Domain #1

Region A:
Residues: [1-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLQRFPRYP LTFGPTPIQP LARLSKHLGG KVHLYAKRED CNSGLAFGGN KTRKLEYLIP  60
   61 EALAQGCDTL VSIGGIQSNQ TRQVAAVAAH LGMKCVLVQE NWVNYSDAVY DRVGNIQMSR 120
  121 ILGADVRLVP DGFDIGFRRS WEDALESVRA AGGKPYAIPA GCSDHPLGGL GFVGFAEEVR 180
  181 AQEAELGFKF DYVVVCSVTG STQAGMVVGF AADGRADRVI GVDASAKPAQ TREQITRIAR 240
  241 QTAEKVGLER DIMRADVVLD ERFAGPEYGL PNEGTLEAIR LCARTEGMLT DPVYEGKSMH 300
  301 GMIEMVRNGE FPEGSRVLYA HLGGVPALNG YSFIFRDG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.522879
Match:	1rqxA
Description:	Crystal structure of ACC Deaminase complexed with Inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cysteine synthase activity	4.72413272579429	bayes_pls_golite062009
catalytic activity	2.38994231321972	bayes_pls_golite062009
1-aminocyclopropane-1-carboxylate deaminase activity	2.36589679524219	bayes_pls_golite062009
tryptophan synthase activity	1.99526226543975	bayes_pls_golite062009
lyase activity	1.87743897464083	bayes_pls_golite062009
cystathionine beta-synthase activity	1.4517088142802	bayes_pls_golite062009
carbon-oxygen lyase activity	0.923824749425553	bayes_pls_golite062009
binding	0.791501201936306	bayes_pls_golite062009
ammonia-lyase activity	0.476674617721478	bayes_pls_golite062009
L-threonine ammonia-lyase activity	0.37325071016009	bayes_pls_golite062009
carbon-nitrogen lyase activity	0.249761226675912	bayes_pls_golite062009
threonine synthase activity	0.0538811973418393	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: