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View Structure Prediction Details

Protein: nhr-109
Organism: Caenorhabditis elegans
Length: 318 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-109.

Description E-value Query
Range
Subject
Range
gi|114627460 - gi|114627460|ref|XP_520345.2| PREDICTED: hypothetical protein [Pan troglodytes]
235.0 [0..1] [316..306]

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Predicted Domain #1
Region A:
Residues: [1-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFTLEQKLA DIRCMCRACR LTKCIEVGMN PVGVRQKPGS FRKSKELISP SSSNHDEFSR  60
   61 MPILSKMKLN YENMRNARKA LHNEVGENVF EEKIPKEINY KESVQQGMKD YTLMPEWVSS 120
  121 CFDEFRTLSA DQKNILFRNS YIPFFMMETA FLSHINNMPD SVIFPSGDYC DMKNLERYYN 180
  181 STNFEKKIST EDIENLFKPF YDNYKRSLLL PMMNLQVDIY EFLTLFTLLH WDTGLVEITD 240
  241 ECLEIGTKVK AEVFKELDFY LTNVKKVAEP SVRIGTIVNL LPAVHKSVRR IQDDMEMTKV 300
  301 FNIFSAPNEF FDLVTGNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.15996699473685 bayes_pls_golite062009
transcription regulator activity 0.46162010671465 bayes_pls_golite062009
protein binding 0.33427459029264 bayes_pls_golite062009
nucleic acid binding 0.15459949087509 bayes_pls_golite062009
DNA binding 0.14395376162921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle