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View Structure Prediction Details

Protein: CE36653
Organism: Caenorhabditis elegans
Length: 788 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE36653.

Description E-value Query
Range
Subject
Range
gi|108873616, gi... - gi|157125482|ref|XP_001654351.1| neurogenic locus notch (notch) [Aedes aegypti], gi|108873616|gb|EAT...
383.0 [0..3] [787..263]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRNLILITL LVASGHGQTP VIGGTCKLGT ADVQIGGKQT QFFLKCETTA DSAEGEGVWV  60
   61 VKSRAAAAPS SVPSVPAENT QPQQHPKARK PASPNICEQD NGARESEVCA VSATCLQAHN 120
  121 DFPSSYLQCD QTTLRWVRKS CQEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1tozA
Description: NMR structure of the human NOTCH-1 ligand binding region
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [145-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLFNFEQQTC IVPKRMSSLS RQQASGLVCT FSSCSNSNPC SVGTCNNGYC CSSGSNSGSA  60
   61 IIVGGGSSNC VGCQNAPQII TIPQNSCPGG GYSVGGCSSG YCATGYSCIQ NQCCPSYNSA 120
  121 PRISVYTCPS GGNAVGACMS GRCASGYTCS NNVCCPQTTT TNPFVCPDGT QAAGGCVNGQ 180
  181 CGTGYTCSNG LCC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.37
Match: 1grzA
Description: A PREORGANIZED ACTIVE SITE IN THE CRYSTAL STRUCTURE OF THE TETRAHYMENA RIBOZYME
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [338-725]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGTSTTVKCL DGSDAVGACI PSCTGDGCGG VQVSYYCGSG YTCTTGNICC PINSCPNGGE  60
   61 VLGPTINGLC PTGYTVQGNL CCSATCTDGS TGLPSVNGVC IDGYSLTNGV CCPASVTCTD 120
  121 EISIGPCTGT GFNGGCPAGY ACDSNQVNCC PVVRYTDESC QVGPAIDGLC PPGYVVVYIP 180
  181 NSPLITNGVN PGTCIDLQCT TGLCLTANQI GDCDTATDAG TCPTGYTCFT NAGICCSTTT 240
  241 FSRLRIGNSR QMAQKPNYGR PLHSYMPPRF GGPSSSCSDG SLSSGPCMNG LCGIGLECQN 300
  301 GKCCSPSSNK PAGLLQSKCP SGDTAVSGCF PNGSCGTGYE CVSSLNLCCP PGQPQTFPSF 360
  361 PGNNNGFNIN NNNRFGSLSM SPRPIGAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.286076792172079 bayes_pls_golite062009
protein binding 0.14494900666454 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [726-788]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQLDGECVGQ AEGLSMCHAG VCQCSPIAYT QGIACVRRKS FQMNDDPVID AANDDKSSSS  60
   61 VSV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle