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View Structure Prediction Details

Protein: alh-6
Organism: Caenorhabditis elegans
Length: 394 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for alh-6.

Description E-value Query
Range
Subject
Range
gi|18858265, gi|... - gi|18858265|ref|NP_571925.1| aldehyde dehydrogenase 1A2 [Danio rerio], gi|15487692|gb|AAL00899.1|AF3...
425.0 [0..48] [393..17]

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Predicted Domain #1
Region A:
Residues: [1-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSFAARRSL ITQKCAASTY SGLTSADFLK KKTNEPILEY RKGSKERQDL EAALAFYSKN  60
   61 ITEVPLRIGD KKITNKLEQK QVIPSDHRST LAKYTYATGE QIQEAIDVAL QARGAWERKP 120
  121 LKERAEILLR AADLAAGKYR MKLNASTMLG QGKNIIQAEI DAACELIDFF RFNAVFAMEL 180
  181 EHYEPISTKI TKNTMQFRGM EGFVAAIAPF NFTAIGGNLP TAPALMGNVS LWKPSNTAVL 240
  241 SNYIIYELLE EAGMPPGILS FLPSDGPVFG DVITASPHLS AVNFTGSVPT FKTIWRKVAE 300
  301 NLDNYVTFPK LIGECGGKNF HFVHPSAHVD AVAAGTARSA WEYSGQKCSA CSRMYAPKSI 360
  361 WPKILEKISA IHKEIKLGDF TGSRWIRLSV GCDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 1cw3A
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 2.27798835091523 bayes_pls_golite062009
oxidoreductase activity 2.06413499546613 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.16959064657074 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1.14755626951491 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle