YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: CE37018
Organism: Caenorhabditis elegans
Length: 600 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE37018.

Description E-value Query
Range
Subject
Range
gi|109462002, gi... - gi|149055799|gb|EDM07230.1| E2F transcription factor 8 [Rattus norvegicus], gi|109462002|ref|XP_0010...
386.0 [0..1] [592..18]

Back

Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTIFGSSNA MFLNIEANKE NIPPGTEFKK ESFVLPEPRV NRTTDPDHEN LLPSPVPRPS  60
   61 PAMSQLSDAS FLSQDGGAVN TSADE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADDDLEVTSR KEKSLGLLCQ RFLIAINEET VGSSTREVHL ETVARKMNVE KRRIYDIVNV  60
   61 MEALDAMQKT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1cf7A
Description: Cell cycle transcription factor E2F-4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [156-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSYYQWQGL ESLPKLMFDL QNEAVEEGLP ERVLRVEQAM CSFTELSSPR GKQGFKDIVG  60
   61 SFVSCTSTPT TPSTSFDSVT VKMEPAGLLE KRSRVDTRDR QGRNSLAQLC RRFLMVLLSN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 2azeA
Description: Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [276-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKNIRKVSLD VASTVLIKDP ETEGFEPPSR SRCRRLYDIA NVLVALGLIK KVHYLFGTKK  60
   61 IPLFVYCGPE P

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.36
Match: 1cf7A
Description: Cell cycle transcription factor E2F-4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.683379929086364 bayes_pls_golite062009
transcription regulator activity 0.16959343932447 bayes_pls_golite062009
nucleic acid binding 0.0949481158963694 bayes_pls_golite062009
DNA binding 0.00746597740509714 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [347-461]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQTGSFDVFQ SVERLLSSSQ NVPQTPIIKA QTDKIVQQIA GFGKRTLSEQ NLTKPSGNTP  60
   61 KIAKIKSAAV RSSPMYMENN LFMFAEVVTA EAAAEKMRYD AFAQLSRTIL GSVAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.154902
Match: 2azeB
Description: Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [462-600]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INSLNAPLTS SQHPMTSRLP PLPMAPLQLP KLPEIPKPQA QKQFTFPATS RPRFNFPDYT  60
   61 PVQSTIRPLV SQMTFPQESS QLHNLDVKPK HLMSNILGES KKFKNNQNTF EHTTSSAFQV 120
  121 VKKGETRPKK VFGEIQNLQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle