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View Structure Prediction Details

Protein: tmd-2
Organism: Caenorhabditis elegans
Length: 639 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tmd-2.

Description E-value Query
Range
Subject
Range
gi|47230640 - gi|47230640|emb|CAF99833.1| unnamed protein product [Tetraodon nigroviridis]
288.0 [0..1] [244..145]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEELQQLRT NASSDLMTDE DFIATIESMG VEAQEREIND LLKAMHENRI VSWDEAERIL  60
   61 METDQTPIKC SLPEQTRPTE PENEVDVDQC IKKLLDNDPS LKEINLNNMK RTPVPAIKRL 120
  121 LEALAYNEHC ERISLANMGL YDHDINVLVT VIEMNQAIKK VNLETNYLSG DFFSKLFKAA 180
  181 LVNESVEEIK AVNQGVSFST QSEKEIIDAI VKNHGLTKIS INFRLPEGRH KVENATLRNG 240
  241 ELKRVKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.69897
Match: 1io0A
Description: Tropomodulin C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [248-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REAAQKARLE AEELAKNPVP KLAPEPKKEP EPKKMAPKIP PAVPKSLVSP EPKPSLAPKA  60
   61 APVIATAPPK STILMKQLSF QRASRESEED TEFVPPPAVP EPPKKLAIPK TFMKKEETPS 120
  121 FQKVAKRPTR QWEPKKQESL EQEEHKETVK EEVKKEEVKE KVPAKVERKH WEPKVAPAPV 180
  181 IDGYAPILDV SGNAAPSTAK PKLDGAPIRA KR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [460-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPITAKNIWE QRMAKIEKKE EKKKPLLSIQ KIREMEKNDV IKKEEDDRLE QLLKKEKEPK  60
   61 KLNNEHRKLF ENGNVAQKKP EPRRHVQKLI AKKPNSILNQ TEPTKIEGPD KQETRPTTVI 120
  121 RRTVIRKKEE MVPSEKPEVS ENEKPKRRLV RKKKVVEGDG MNGTNGHQSH LTSAPPQAVH 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle