YRC Public Data Repository - Protein Structure Prediction

Protein:	VTC4
Organism:	Saccharomyces cerevisiae
Length:	721 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VTC4.

Description	E-value	Query Range	Subject Range
gi\|207343937 - gi\|207343937\|gb\|EDZ71240.1\| YJL012Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190409478 - gi\|190409478\|gb\|EDV12743.1\| vacuolar transporter chaperone 4 [Saccharomyces cerevisiae RM11-1a] gi\|151945066 - gi\|151945066\|gb\|EDN63317.1\| vacuolar transporter chaperone [Saccharomyces cerevisiae YJM789] VTC4_YEAST - Vacuolar transporter chaperone 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VTC4 PE... VTC4 - Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) comp...	0.0	[1..721]	[1..721]
gi\|42545891, gi\|... - gi\|46107238\|ref\|XP_380678.1\| hypothetical protein FG00502.1 [Gibberella zeae PH-1], gi\|42545891\|gb\|E...	0.0	[1..714]	[1..771]
gi\|45201412, gi\|... - gi\|45201412\|ref\|NP_986982.1\| AGR316Cp [Ashbya gossypii ATCC 10895], gi\|44986346\|gb\|AAS54806.1\| AGR31... gi\|44986346 - gi\|44986346\|gb\|AAS54806.1\| AGR316Cp [Ashbya gossypii ATCC 10895]	0.0	[1..718]	[1..712]
gi\|32416676, gi\|... - gi\|32416676\|ref\|XP_328816.1\| hypothetical protein [Neurospora crassa], gi\|28925580\|gb\|EAA34604.1\| hy... gi\|85111234 - gi\|85111234\|ref\|XP_963840.1\| hypothetical protein [Neurospora crassa OR74A]	0.0	[1..715]	[39..814]
VTC4_SCHPO - Vacuolar transporter chaperone 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=vtc4 PE=1... vtc4 - vacuolar transporter chaperone (VTC) complex subunit	0.0	[1..720]	[1..721]
gi\|238881520 - gi\|238881520\|gb\|EEQ45158.1\| vacuolar transporter chaperone 4 [Candida albicans WO-1] gi\|46432897, gi\|... - gi\|68489124\|ref\|XP_711583.1\| hypothetical protein CaO19.3363 [Candida albicans SC5314], gi\|68489079\|... orf19.10871, orf... - VTC4 CGDID:CAL0004171 Assembly 19, Contig19-10174 (4235, 2106) CDS, reverse complemented, translated...	0.0	[1..716]	[1..708]
gi\|49095638, gi\|... - gi\|67537946\|ref\|XP_662747.1\| hypothetical protein AN5143.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	0.0	[1..702]	[1..723]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFGEHLSKS LIRQYSYYYI SYDDLKTELE DNLSKNNGQW TQELETDFLE SLEIELDKVY  60
   61 TFCKVKHSEV FRRVKEVQEQ VQHTVRLLDS NNPPTQLDFE ILEEELSDII ADVHDLAKFS 120
  121 RLNYTGFQKI IKKHDKKTGF ILKPVFQVRL DSKPFFKENY DELVVKISQL YDIARTSGRP 180
  181 IKGDSSAG

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	49.207608
Match:	PF03105.7
Description:	No description for PF03105.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [189-399]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKQQNFVRQT TKYWVHPDNI TELKLIILKH LPVLVFNTNK EFEREDSAIT SIYFDNENLD  60
   61 LYYGRLRKDE GAEAHRLRWY GGMSTDTIFV ERKTHREDWT GEKSVKARFA LKERHVNDFL 120
  121 KGKYTVDQVF AKMRKEGKKP MNEIENLEAL ASEIQYVMLK KKLRPVVRSF YNRTAFQLPG 180
  181 DARVRISLDT ELTMVREDNF DGVDRTHKNW R

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [400-596]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTDIGVDWPF KQLDDKDICR FPYAVLEVKL QTQLGQEPPE WVRELVGSHL VEPVPKFSKF  60
   61 IHGVATLLND KVDSIPFWLP QMDVDIRKPP LPTNIEITRP GRSDNEDNDF DEDDEDDAAL 120
  121 VAAMTNAPGN SLDIEESVGY GATSAPTSNT NHVVESANAA YYQRKIRNAE NPISKKYYEI 180
  181 VAFFDHYFNG DQISKIP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [597-721]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGTTFDTQIR APPGKTICVP VRVEPKVYFA TERTYLSWLS ISILLGGVST TLLTYGSPTA  60
   61 MIGSIGFFIT SLAVLIRTVM VYAKRVVNIR LKRAVDYEDK IGPGMVSVFL ILSILFSFFC 120
  121 NLVAK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.892	N/A	N/A	a.2.2	Ribosomal protein L29 (L29p)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits