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View Structure Prediction Details

Protein: IRC5
Organism: Saccharomyces cerevisiae
Length: 853 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IRC5.

Description E-value Query
Range
Subject
Range
IRC5 - Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increase...
442.0 [0..1] [777..1]

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Predicted Domain #1
Region A:
Residues: [1-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRCSNAALM TVVEDAVGAR VAARTRNMSN GVNYREKEVN DLTADISDSD SDLDSEDNKH  60
   61 GKGDNDTAPI WLQDDVHSDE DIQLDSEDDS DTEAVQAQVV DKLAKDTKSE QKSLDDELSE 120
  121 MDTKTVSLKL KKLNEFVRQS QVYSSIIADT LLHRSNEVAN ANTKDNSNSD DEEHSSKKRK 180
  181 TKKKSITDFF KKQKKNEDTT TQNGAPDDAA IKQPRLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 2gjkA
Description: No description for 2gjkA was found.

Predicted Domain #2
Region A:
Residues: [218-775]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNCILKPYQL EGLNWLITLY ENGLNGILAD EMGLGKTVQS IALLAFIYEM DTKGPFLVTA  60
   61 PLSTLDNWMN EFAKFAPDLP VLKYYGTNGY KERSAKLKNF FKQHGGTGIV ITSYEIILRD 120
  121 TDLIMSQNWK FLIVDEGHRL KNINCRLIKE LKKINTSNRL LLTGTPLQNN LAELWSLLNF 180
  181 IMPDIFADFE IFNKWFDFDS LNLGSGSNSE ALNKLINDEL QKNLISNLHT ILKPFLLRRL 240
  241 KKVVLANILP PKREYIINCP MTSAQEKFYK AGLNGKLKKT MFKELIKDFF TLNDEYIGHV 300
  301 SNRSIRDFIN YKLSGNETSN TDNKINPTLL QMDKLYKKNL QMEISNKKLQ NMMMQLRQII 360
  361 DSTFLFYFPY LHPEDLTLET LLKTSGKLQI LQKLIPPLIS EGHKVLIYSQ FVNMLDLIED 420
  421 WCDLNSFATF RIDGSVNNET RKDQLEKFNS SKDKHNIFLL STRAAGLGIN LVGADTVVLF 480
  481 DSDWNPQVDL QAMDRCHRIG QESPVIVYRL CCDNTIEHVI LTRAANKRNL ERMVIQMGKF 540
  541 NNLKKLALNE GSFLKANK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 1z63A
Description: Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [776-853]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGVNVTNKDL VQELSMLLMS DESNIGFENG GQKENKATEG QLTDKEVEEL TNRSLEAYKA  60
   61 NRVVDLPHVK LFETTSGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 2v1xA
Description: No description for 2v1xA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle