YRC Public Data Repository - Protein Structure Prediction

Protein:	SEC62
Organism:	Saccharomyces cerevisiae
Length:	274 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC62.

Description	E-value	Query Range	Subject Range
SEC62 - Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/Bi... gi\|207340568 - gi\|207340568\|gb\|EDZ68878.1\| YPL094Cp-like protein [Saccharomyces cerevisiae AWRI1631]	3.0E-95	[1..274]	[10..283]
gi\|33086592, gi\|... - gi\|77735350\|ref\|NP_001029301.1\| SEC62 homolog [Rattus norvegicus], gi\|33086592\|gb\|AAP92608.1\| Ab2-29...	1.0E-78	[13..272]	[222..526]
gi\|28924204, gi\|... - gi\|32411415\|ref\|XP_326188.1\| hypothetical protein [Neurospora crassa], gi\|28924204\|gb\|EAA33359.1\| co... gi\|85108529 - gi\|85108529\|ref\|XP_962595.1\| hypothetical protein NCU06333 [Neurospora crassa OR74A]	5.0E-78	[5..259]	[102..355]
SEC62_MOUSE - Translocation protein SEC62 OS=Mus musculus GN=Sec62 PE=1 SV=1	1.0E-74	[13..272]	[15..319]
gi\|67540198, gi\|... - gi\|67540198\|ref\|XP_663873.1\| hypothetical protein AN6269.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	2.0E-73	[6..241]	[89..331]
gi\|46123599, gi\|... - gi\|46123599\|ref\|XP_386353.1\| hypothetical protein FG06177.1 [Gibberella zeae PH-1], gi\|42551898\|gb\|E...	2.0E-70	[5..241]	[100..328]
SEC62_SCHPO - Translocation protein sec62 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sec62 PE=3 SV=... sec62 - ER protein translocation subcomplex subunit Sec62	1.0E-69	[24..271]	[23..251]
gi\|71014085, gi\|... - gi\|71014085\|ref\|XP_758693.1\| hypothetical protein UM02546.1 [Ustilago maydis 521], ref\|XP_400161.1\| ...	5.0E-69	[19..237]	[115..314]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVGPGSNA GASVNGGSAT AIATLLRNHK ELKQRQGLFQ AKQTDFFRYK RFVRALHSEE  60
   61 YANKSARQPE IYPTIPSNKI EDQLKSREIF IQLIKAQMVI PVKKL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [106-274]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSQECKEHGL KPSKDFPHLI VSNKAQLEAD EYFVWNYNPR TYMDYLIVIG VVSIILALVC  60
   61 YPLWPRSMRR GSYYVSLGAF GILAGFFAVA ILRLILYVLS LIVYKDVGGF WIFPNLFEDC 120
  121 GVLESFKPLY GFGEKDTYSY KKKLKRMKKK QAKRESNKKK AINEKAEQN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits